Preparation and Characterization of Polyacrylamide/Silk Fibroin/Graphene Oxide Composite Hydrogel for Peripheral Nerve Regeneration

2016 ◽  
Vol 6 (9) ◽  
pp. 682-689 ◽  
Author(s):  
Yan Kong ◽  
Yinxin Zhao ◽  
Bing Ji ◽  
Beibei Shi ◽  
Siying Wei ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Silk Fibroin ◽  
Peripheral Nerve Regeneration ◽  
Composite Hydrogel ◽  
Oxide Composite

scholarly journals The influence of reduced graphene oxide on stem cells: a perspective in peripheral nerve regeneration

2021 ◽  
Vol 8 (4) ◽  
Author(s):  
Xiangyun Yao ◽  
Zhiwen Yan ◽  
Xu Wang ◽  
Huiquan Jiang ◽  
Yun Qian ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Stem Cells ◽  
Graphene Oxide ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Reduced Graphene Oxide ◽  
Peripheral Nerve Regeneration ◽  
Embryonic Stem ◽  
Composite Scaffolds ◽  
Reduced Graphene

Abstract Graphene and its derivatives are fascinating materials for their extraordinary electrochemical and mechanical properties. In recent decades, many researchers explored their applications in tissue engineering and regenerative medicine. Reduced graphene oxide (rGO) possesses remarkable structural and functional resemblance to graphene, although some residual oxygen-containing groups and defects exist in the structure. Such structure holds great potential since the remnant-oxygenated groups can further be functionalized or modified. Moreover, oxygen-containing groups can improve the dispersion of rGO in organic or aqueous media. Therefore, it is preferable to utilize rGO in the production of composite materials. The rGO composite scaffolds provide favorable extracellular microenvironment and affect the cellular behavior of cultured cells in the peripheral nerve regeneration. On the one hand, rGO impacts on Schwann cells and neurons which are major components of peripheral nerves. On the other hand, rGO-incorporated composite scaffolds promote the neurogenic differentiation of several stem cells, including embryonic stem cells, mesenchymal stem cells, adipose-derived stem cells and neural stem cells. This review will briefly introduce the production and major properties of rGO, and its potential in modulating the cellular behaviors of specific stem cells. Finally, we present its emerging roles in the production of composite scaffolds for nerve tissue engineering.

Preparation and characterization of collagen-based composite conduit for peripheral nerve regeneration

2009 ◽  
Vol 112 (6) ◽  
pp. 3652-3662 ◽  
Author(s):  
Wang Xiangmei ◽  
Zhang Jing ◽  
Chen Hao ◽  
Wang Qingrui
Keyword(s):  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration

Preparation and characterization of collagen/silica composite scaffolds for peripheral nerve regeneration

2014 ◽  
Vol 21 (5) ◽  
pp. 699-708 ◽  
Author(s):  
Shangfei Jing ◽  
Dianming Jiang ◽  
Shuzheng Wen ◽  
Jihong Wang ◽  
Chenyuan Yang
Keyword(s):  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Composite Scaffolds ◽  
Silica Composite
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