Enhanced Cancer-Targeted Delivery Using Engineered High-Density Lipoprotein-Based Nanocarriers

2007 ◽  
Vol 3 (4) ◽  
pp. 367-376 ◽  
Author(s):  
Ian R. Corbin ◽  
Juan Chen ◽  
Weiguo Cao ◽  
Hui Li ◽  
Sissel Lund-Katz ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Targeted Delivery ◽  
Density Lipoprotein ◽  
High Density

scholarly journals Targeted Delivery of Small Interfering RNA Using Reconstituted High-Density Lipoprotein Nanoparticles

Neoplasia ◽  
2011 ◽  
Vol 13 (4) ◽  
pp. 309-IN8 ◽  
Author(s):  
Mian M.K. Shahzad ◽  
Lingegowda S. Mangala ◽  
Hee Dong Han ◽  
Chunhua Lu ◽  
Justin Bottsford-Miller ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Targeted Delivery ◽  
Small Interfering Rna ◽  
Density Lipoprotein ◽  
High Density ◽  
Interfering Rna

scholarly journals Synthetic High-Density Lipoprotein-Mediated Targeted Delivery of Liver X Receptors Agonist Promotes Atherosclerosis Regression

EBioMedicine ◽  
2018 ◽  
Vol 28 ◽  
pp. 225-233 ◽  
Author(s):  
Yanhong Guo ◽  
Wenmin Yuan ◽  
Bilian Yu ◽  
Rui Kuai ◽  
Wenting Hu ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Targeted Delivery ◽  
Density Lipoprotein ◽  
High Density ◽  
Liver X Receptors ◽  
X Receptors

Targeted delivery of garcinia glycosides by reconstituted high-density lipoprotein nano-complexes

2018 ◽  
Vol 35 (2) ◽  
pp. 115-120 ◽  
Author(s):  
Chang Liu ◽  
Zijun Zhou ◽  
Ye Chen ◽  
Ju Liu ◽  
Yang Wang ◽  
...  
Keyword(s):  
High Density Lipoprotein ◽  
Targeted Delivery ◽  
Density Lipoprotein ◽  
High Density

Triglyceride to high density lipoprotein cholesterol ratio, total cholesterol to high density lipoprotein cholesterol ratio and low ankle brachial index in an elderly population

VASA ◽  
2014 ◽  
Vol 43 (3) ◽  
pp. 189-197 ◽  
Author(s):  
Yiqiang Zhan ◽  
Jinming Yu ◽  
Rongjing Ding ◽  
Yihong Sun ◽  
Dayi Hu
Keyword(s):  
High Density Lipoprotein ◽  
Total Cholesterol ◽  
High Density Lipoprotein Cholesterol ◽  
Ankle Brachial Index ◽  
Density Lipoprotein ◽  
High Density ◽  
Lipoprotein Cholesterol ◽  
Lipid Lowering ◽  
Cholesterol Ratio ◽  
Potential Biomarker

Background: The associations of triglyceride (TG) to high-density lipoprotein cholesterol ratio (HDL‑C) and total cholesterol (TC) to HDL‑C ratio and low ankle brachial index (ABI) were seldom investigated. Patients and methods: A population based cross-sectional survey was conducted and 2982 participants 60 years and over were recruited. TG, TC, HDL‑C, and low-density lipoprotein cholesterol (LDL-C) were assessed in all participants. Low ABI was defined as ABI ≤ 0.9 in either leg. Multiple logistic regression models were applied to study the association between TG/HDL‑C ratio, TC/HDL‑C ratio and low ABI. Results: The TG/HDL‑C ratios for those with ABI > 0.9 and ABI ≤ 0.9 were 1.28 ± 1.20 and 1.48 ± 1.13 (P < 0.0001), while the TC/HDL‑C ratios were 3.96 ± 1.09 and 4.32 ± 1.15 (P < 0.0001), respectively. After adjusting for age, gender, body mass index, obesity, current drinking, physical activity, hypertension, diabetes, lipid-lowering drugs, and cardiovascular disease history, the odds ratios (ORs) with 95 % confidence intervals (CIs) of low ABI for TG/HDL‑C ratio and TC/HDL‑C ratio were 1.10 (0.96, 1.26) and 1.34 (1.14, 1.59) in non-smokers. When TC was further adjusted, the ORs (95 % CIs) were 1.40 (0.79, 2.52) and 1.53 (1.21, 1.93) for TG/HDL‑C ratio and TC/HDL‑C ratio, respectively. Non-linear relationships were detected between TG/HDL‑C ratio and TC/HDL‑C ratio and low ABI in both smokers and non-smokers. Conclusions: TC/HDL‑C ratio was significantly associated with low ABI in non-smokers and the association was independent of TC, TG, HDL‑C, and LDL-C. TC/HDL‑C might be considered as a potential biomarker for early peripheral arterial disease screening.

Nonenzymatic glucosylation of high-density lipoprotein accelerates its catabolism in guinea pigs

Diabetes ◽  
1982 ◽  
Vol 31 (11) ◽  
pp. 1029-1032 ◽  
Author(s):  
J. L. Witztum ◽  
M. Fisher ◽  
T. Pietro ◽  
U. P. Steinbrecher ◽  
R. L. Elam
Keyword(s):  
High Density Lipoprotein ◽  
Guinea Pigs ◽  
Density Lipoprotein ◽  
High Density

High density lipoprotein structure

10.2741/1077 ◽  
2003 ◽  
Vol 8 (4) ◽  
pp. d1044-1054 ◽  
Author(s):  
Michael C Phillips
Keyword(s):  
High Density Lipoprotein ◽  
Density Lipoprotein ◽  
High Density
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