scholarly journals Hepatocellular carcinoma originating in the caudate lobe diagnosed by endoscopic ultrasound-guided fine-needle aspiration

2015 ◽  
Vol 86 (1) ◽  
pp. 220-221
Author(s):  
Kazuki Nomoto ◽  
Makoto Nishimura ◽  
Harutaka Kambayashi ◽  
Kenichiro Nakajima ◽  
Yasuko Ushio ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Caudate Lobe ◽  
Ultrasound Guided ◽  
Fine Needle

scholarly journals Diagnosis of metastatic fibrolamellar hepatocellular carcinoma by endoscopic ultrasound-guided fine needle aspiration

CytoJournal ◽  
2011 ◽  
Vol 8 ◽  
pp. 2 ◽  
Author(s):  
Amanda Crowe ◽  
Carrie S. Knight ◽  
Darshana Jhala ◽  
Steve J. Bynon ◽  
Nirag C. Jhala
Keyword(s):  
Hepatocellular Carcinoma ◽  
Endoscopic Ultrasound ◽  
Fine Needle Aspiration ◽  
Needle Aspiration ◽  
Mediastinal Lymphadenopathy ◽  
Prior History ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
History Of ◽  
Cytological Features

The fibrolamellar variant of hepatocellular carcinoma (FL-HCC) is distinguished from other hepatocellular carcinomas (HCC) by its unique clinical and pathologic features. Cytological features for this tumor on fine needle aspiration (FNA) of primary tumors have been described earlier. We present here a unique case of metastatic FL-HCC diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of mediastinal adenopathy. A 32-year-old woman with a history of oral contraceptive use presented with nausea and severe abdominal pain but no ascites or stigmata of cirrhosis. She had a past history of resection of a liver lesion. Serial computed tomography scans revealed mediastinal lymphadenopathy and the patient was referred for endoscopic ultrasound (EUS). A transesophageal EUS-FNA was performed and tissue was collected for cytological evaluation by an on-site pathologist with no knowledge of prior history. Based on morphology correlated with prior history received later, a final diagnosis of metastatic FL-HCC in the retrocardiac lymph node was rendered on the EUS-FNA samples. There are very few reports in the literature where a diagnosis of FL-HCC is rendered at unusual sites. This case highlights that EUS-FNA is a relatively non-invasive, rapid, accurate and effective modality in obtaining tissue from otherwise hard-to-reach areas. It also suggests that metastasis of FL-HCC can be observed in mediastinal nodes and that diagnosis based on cytological features can be rendered even when the tumor is identified at unusual locations.

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