scholarly journals Extubation Readiness in Critically Ill Stroke Patients

Stroke ◽  
2019 ◽  
Vol 50 (8) ◽  
pp. 1981-1988 ◽  
Author(s):  
Sonja Suntrup-Krueger ◽  
Sarah Schmidt ◽  
Tobias Warnecke ◽  
Corinna Steidl ◽  
Paul Muhle ◽  
...  
2011 ◽  
Vol 26 (3) ◽  
pp. 273-279 ◽  
Author(s):  
Yusuke Kasuya ◽  
James L. Hargett ◽  
Rainer Lenhardt ◽  
Michael F. Heine ◽  
Anthony G. Doufas ◽  
...  

Author(s):  
Dongmei Wang ◽  
Zhenzhou Lin ◽  
Ling Xie ◽  
Kaibin Huang ◽  
Zhong Ji ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (9) ◽  
pp. e72971 ◽  
Author(s):  
Ying-Chih Huang ◽  
Yi-Ling Wu ◽  
Ming-Hsueh Lee ◽  
Jiann-Der Lee ◽  
Chih-Ying Wu ◽  
...  

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
B Zhang ◽  
Q Zhu ◽  
Z Lu

Abstract Background Although there are many indicators to assess nutritional status, a more comprehensive and objective indicator is still needed in clinical practice. In this study, we evaluated the relationship between the prognostic nutritional index (PNI) and clinical outcomes in patients with critically ill stroke. Methods Subjects who were diagnosed as stroke in the Beth Israel Deaconess Medical Center between 2001 and 2012 were identified from the Medical Information Mart for Intensive Care (MIMIC) III database. PNI was calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3). The multivariate logistic regression and the Cox regression analysis were performed to assess the impact of PNI on 3-month and 4-year mortality in stroke patients. Results A total of 624 subjects were included in this study. Compared with the high-PNI group, those in the Low PNI group had lower body mass index (BMI), hemoglobin, neutrophil count, lymphocyte count and albumin. On the contrary, Age, Blood urea nitrogen (BUN), Creatinine (Cre), simplified acute physiologic scoreII (SAPSII) score and sequential organ failure assessment (SOFA) score of the low PNI group were higher than the high PNI group. After adjusting for other confounders, PNI was independently associated with 3-month mortality (adjusted odds ratio = 1.910; 95% confidence interval, 1.244–2.933; P=0.003). By the Kaplan-Meier analysis, patients in the low PNI group presented significantly shorter survival time and higher death rate. The Cox regression model indicated low PNI as an independent risk factor of 4-year all-cause mortality of stroke patients (hazard ratio = 1.824; 95% CI, 1.340–2.483; P<0.001). Conclusions Low PNI is independently associated with short-term and long-term prognosis in patients with critically ill stroke. FUNDunding Acknowledgement Type of funding sources: None.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Neha S Dangayach ◽  
Stephen A Griffiths ◽  
Marta Melis ◽  
Jiyeoun Yoo ◽  
Lara Marcuse ◽  
...  

Introduction: Patients with severe acute stroke can suffer secondary neurological injury due to a variety of causes. The clinical impact of electrographic seizures among critically-ill stroke patients remains unclear. Methods: We retrospectively analyzed a cohort of consecutive stroke patients admitted to the Neuroscience Intensive Care Unit (NSICU) at the Mount Sinai Hospital who underwent ≥24 hours of continuous video EEG (cEEG) monitoring for alteration in level of consciousness or suspected non-convulsive seizures between May 2013 and June 2015. Results: Of 106 consecutive severe stroke patients admitted to the NSICU who underwent cEEG monitoring, 15 (14%) had clinical or electrographic seizures. The median duration of cEEG monitoring was 1.2 days. Observed seizures included purely electrographic seizures with no clinical correlate in 53%, subtle twitching or altered mental status in 33%, and generalized tonic-clonic seizures with an EEG correlate in 13%. Generalized or lateralized periodic discharges (PEDs) were present in 93% (14/15) of patients in the seizure group, compared to 20% (18/89) in the non-seizure group (P= 0.00). The survival rate at discharge was 53% in the seizure group compared to 73% in the non-seizure group (p = 0.12). Mean ICU length of stay was 16 days in both groups. Of the 11 survivors in the seizure group 100% were severely disabled at discharge (mRS 4 or 5) compared to 75% of the 65 survivors in the non-seizure group.(P=0.06). Conclusion: Critically-ill stroke patients with clinical or electrographic seizures in the ICU tend to have higher mortality and worse functional outcome at the time of discharge. PEDS are an important marker of patients at high risk for ictal activity. Careful identification of acute stroke patients that might benefit from seizure prophylaxis is warranted.


2017 ◽  
Vol 39 (11) ◽  
pp. 959-964 ◽  
Author(s):  
Robert Patejdl ◽  
Matthias Kästner ◽  
Stephan Kolbaske ◽  
Matthias Wittstock

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