scholarly journals Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate

Stroke ◽  
2017 ◽  
Vol 48 (8) ◽  
pp. 2301-2305 ◽  
Author(s):  
Romain Goulay ◽  
Julien Flament ◽  
Maxime Gauberti ◽  
Michael Naveau ◽  
Nolwenn Pasquet ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Nonhuman Primate ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation ◽  
Brain Parenchymal

scholarly journals Quantification of the Disturbed Cerebrospinal Fluid Circulation and the Elasticity after Subarachnoid Hemorrhage, using Infusion Studies

1986 ◽  
Vol 26 (2) ◽  
pp. 153-159
Author(s):  
Kouichi KITAMI ◽  
Akifumi SUZUKI ◽  
Hideo TSUCHIDA ◽  
Hiromi NISHIMURA ◽  
Nobuyuki YASUI
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation

Disturbances of Cerebrospinal Fluid Circulation during the Acute Stage of Subarachnoid Hemorrhage

Neurosurgery ◽  
1983 ◽  
Vol 12 (4) ◽  
pp. 435-438 ◽  
Author(s):  
Thomas Dóczi ◽  
Zoltán Nemessányi ◽  
Zsuzsa Szegváry ◽  
Endre Huszka
Keyword(s):  
Cerebrospinal Fluid ◽  
Subarachnoid Hemorrhage ◽  
Clinical Condition ◽  
Acute Stage ◽  
Normal Flow ◽  
Fluid Circulation ◽  
Csf Flow ◽  
Cerebrospinal Fluid Circulation ◽  
Csf Circulation ◽  
Flow Disturbances

Abstract Radioisotope cisternography was performed and the erythrocyte and hemoglobin contents of the cerebrospinal fluid (CSF) were determined within the first 4 days after subarachnoid hemorrhage in 42 patients. The clinical condition of the patients was related to the severity of the CSF circulation disturbances. Thirty-five patients had some degree of disturbance of CSF flow, and only 2 of the 42 patients had normal flow. In 5 cases the cisternograms were inconclusive. The severity of CSF circulation disturbances correlated well with clinical condition. No relationship was found between the number of erythrocytes in the CSF and the development of CSF circulation disturbances. The CSF erythrocyte content did not correlate with the clinical condition. It is suggested that flow disturbances of the CSF during the acute stage of subarachnoid hemorrhage might play an important role in the pathomechanism of the disease.

scholarly journals The orthopedic characterization of cfap298tm304 mutants validate zebrafish to faithfully model human AIS

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Marie-Hardy Laura ◽  
Cantaut-Belarif Yasmine ◽  
Pietton Raphaël ◽  
Slimani Lotfi ◽  
Pascal-Moussellard Hugues
Keyword(s):  
Cerebrospinal Fluid ◽  
Three Dimensional ◽  
Fluid Circulation ◽  
Micro Computed Tomography ◽  
Csf Flow ◽  
Cerebrospinal Fluid Circulation ◽  
Clinical Criteria ◽  
Brain And Spinal Cord ◽  
The Brain

AbstractCerebrospinal fluid (CSF) circulation relies on the beating of motile cilia projecting in the lumen of the brain and spinal cord cavities Mutations in genes involved in cilia motility disturb cerebrospinal fluid circulation and result in scoliosis-like deformities of the spine in juvenile zebrafish. However, these defects in spine alignment have not been validated with clinical criteria used to diagnose adolescent idiopathic scoliosis (AIS). The aim of this study was to describe, using orthopaedic criteria the spinal deformities of a zebrafish mutant model of AIS targeting a gene involved in cilia polarity and motility, cfap298tm304. The zebrafish mutant line cfap298tm304, exhibiting alteration of CSF flow due to defective cilia motility, was raised to the juvenile stage. The analysis of mutant animals was based on micro-computed tomography (micro-CT), which was conducted in a QUANTUM FX CALIPER, with a 59 µm-30 mm protocol. 63% of the cfap298tm304 zebrafish analyzed presented a three-dimensional deformity of the spine, that was evolutive during the juvenile phase, more frequent in females, with a right convexity, a rotational component and involving at least one dislocation. We confirm here that cfap298tm304 scoliotic individuals display a typical AIS phenotype, with orthopedic criteria mirroring patient’s diagnosis.

Experimental Studies Relating to Diagnostic Imaging in Disorders of Cerebrospinal Fluid Circulation

1980 ◽  
pp. 381-404 ◽  
Author(s):  
A. Everette James ◽  
Gary R. Novak ◽  
Ernst-Peter Strecker ◽  
Barry B. Burns ◽  
Francisco Correa-Paz ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Diagnostic Imaging ◽  
Experimental Studies ◽  
Fluid Circulation ◽  
Cerebrospinal Fluid Circulation
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