scholarly journals Transcranial Direct Current Stimulation Potentiates Improvements in Functional Ability in Patients With Chronic Stroke Receiving Constraint-Induced Movement Therapy

Stroke ◽  
2017 ◽  
Vol 48 (1) ◽  
pp. 229-232 ◽  
Author(s):  
Krystian Figlewski ◽  
Jakob Udby Blicher ◽  
Jesper Mortensen ◽  
Kåre Eg Severinsen ◽  
Jørgen Feldbæk Nielsen ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Suellen M. Andrade ◽  
Larissa M. Batista ◽  
Lídia L. R. F. Nogueira ◽  
Eliane A. de Oliveira ◽  
Antonio G. C. de Carvalho ◽  
...  

Objective.We compared the effects of transcranial direct current stimulation at different cortical sites (premotor and motor primary cortex) combined with constraint-induced movement therapy for treatment of stroke patients.Design.Sixty patients were randomly distributed into 3 groups: Group A, anodal stimulation on premotor cortex and constraint-induced movement therapy; Group B, anodal stimulation on primary motor cortex and constraint-induced movement therapy; Group C, sham stimulation and constraint-induced movement therapy. Evaluations involved analysis of functional independence, motor recovery, spasticity, gross motor function, and muscle strength.Results.A significant improvement in primary outcome (functional independence) after treatment in the premotor group followed by primary motor group and sham group was observed. The same pattern of improvement was highlighted among all secondary outcome measures regarding the superior performance of the premotor group over primary motor and sham groups.Conclusions.Premotor cortex can contribute to motor function in patients with severe functional disabilities in early stages of stroke. This study was registered in ClinicalTrials.gov database (NCT 02628561).


2020 ◽  
Vol 83 (8) ◽  
pp. 523-529
Author(s):  
Maricel A Garrido ◽  
Evelyn A Άlvarez ◽  
Fabrizio L Acevedo ◽  
Álvaro I Moyano ◽  
Natalia P Castillo ◽  
...  

Introduction Upper limb motor impairment after a stroke is an important sequela. Constraint-induced movement therapy is a rehabilitation approach that has strong evidence. The incorporation of transcranial direct-current stimulation has been proposed; however, there is a lack of studies that confirm its benefits. The principal aim is to compare the effectiveness of 7 days of active versus sham bi-hemispheric transcranial direct-current stimulation, combined with modified constraint-induced movement therapy, for motor and functional recovery of the hemiparetic upper limb in subacute stroke patients. Method/design Randomized, double blind, sham-controlled, parallel group clinical trial in two stroke units. Participants: adults over 18 years, at least 2 days post unihemispheric stroke event, with hemiparesis, and without severe pain, aphasia or cognitive impairment. Intervention: Patients will receive 7 days of continuous therapy and be assigned to one of the treatment groups: active bi-hemispheric transcranial direct-current stimulation or sham bi-hemispheric transcranial direct-current stimulation. Measurement: Evaluations will take place at days 0, 5, 7 and 10, and at 3rd months. The Fugl-Meyer Assessment – Upper Extremity, Wolf Motor Function Test, Functional Independence Measure and Stroke Impact Scale are considered. Discussion Modified constraint-induced movement therapy plus transcranial direct-current stimulation in subacute stroke patients with hemiparesis could maximize motor and functional recovery. Trial registration: ClinicalTrials.gov identifier NCT03452254.


2021 ◽  
Vol 34 (2) ◽  
pp. 96-106
Author(s):  
Andrew T. DeMarco ◽  
Elizabeth Dvorak ◽  
Elizabeth Lacey ◽  
Catherine J. Stoodley ◽  
Peter E. Turkeltaub

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