Acute Ischemic Stroke and Long-Term Outcome After Thrombolysis

Stroke ◽  
2014 ◽  
Vol 45 (10) ◽  
pp. 3070-3072 ◽  
Author(s):  
Marie Louise Schmitz ◽  
Claus Z. Simonsen ◽  
Heidi Hundborg ◽  
Hanne Christensen ◽  
Karsten Ellemann ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Term Outcome ◽  
Long Term Outcome

Abstract TP448: High Residual Platelet Reactivity (hrpr) for Adenosine Diphosphate (adp) Stimuli is a Determinant Factor for Long-term Outcomes in Acute Ischemic Stroke With Anti-platelet Agents

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Jae-Kwan Cha ◽  
Eun-Kyu Kim
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Primary Endpoint ◽  
Platelet Reactivity ◽  
Large Artery ◽  
Vascular Events ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Platelet Aggregometry

Background and Purpose: High residual platelet activation (HRPA) after ADP stimuli has associated with recurrent vascular events in acute atherothrombosis with the use of antiplatelet agents (APAs). However, there has been little evidence supporting this association in acute ischemic stroke (AIS). In this study, we evaluated the influences of HRPR after ADP stimuli on the 1-year incidence of recurrent cardiovascular events and mortality in AIS with APAs. Methods: We conducted an observational, referral center cohort study on 968 AIS patients with APAs from January 2010 to December 2013 who were evaluated using optical platelet aggregometry (OPA). All patients received the dual APA combination of aspirin and clopidogrel or aspirin alone. We evaluated their platelet function 5 days after hospital admission using OPA. HRPR after ADP stimuli was defined as platelet aggregation of 70% or greater according to OPA after 10 μM ADP stimuli. Results: The primary endpoint was a composite of all causes of death, myocardial infarction, and stroke at the 1-year follow-up. The secondary endpoints were each component of the primary endpoint. The event rate of primary endpoint was 11.3% (109/968). Its rate was significantly higher in the patients with HRPR (16.7%) than in those without (9.7%). HPRP was independently associated with the primary endpoint (OR=1.97, CI 1.22 to 3.18, p<0.01). According to the AIS subtype, the presence of HRPR was independently significant for the occurrence of the primary endpoint in the large artery atherosclerosis (LAA) subtype only (OR=2.26, CI 1.15 to 4.45, P=0.02). Conclusions: In this study, the presence of HRPR after ADP stimuli is associated with a poor long-term outcome after acute ischemic stroke. In particular, the influence of this factor might be more prominent in LAA compared with other types of AIS.

THE TYPE OF ATRIAL FIBRILLATION IS ASSOCIATED WITH LONG-TERM OUTCOME IN PATIENTS WITH ACUTE ISCHEMIC STROKE

2011 ◽  
Vol 22 ◽  
pp. S68-S69
Author(s):  
George Ntaios ◽  
Anastasia Vemmou ◽  
Eleni Koromboki ◽  
Paraskevi Savvari ◽  
Michalis Saliaris ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Term Outcome ◽  
Long Term Outcome

Long-term outcome changes after mechanical thrombectomy for anterior circulation acute ischemic stroke

2019 ◽  
Vol 267 (4) ◽  
pp. 1026-1034
Author(s):  
Hannah Fuhrer ◽  
Lisa Forner ◽  
Pascal Pruellage ◽  
Susanne Weber ◽  
Lena-Alexandra Beume ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Mechanical Thrombectomy ◽  
Anterior Circulation ◽  
Term Outcome ◽  
Long Term Outcome

Prognostic Value of 24-H ABPM in Acute Ischemic Stroke for Short-, Medium-, and Long-Term Outcome: A Systematic Review and Meta-Analysis

2015 ◽  
Vol 10 (7) ◽  
pp. 1000-1007 ◽  
Author(s):  
Nikolaos Kakaletsis ◽  
George Ntaios ◽  
Haralampos Milionis ◽  
Anna-Bettina Haidich ◽  
Konstantinos Makaritsis ◽  
...  
Keyword(s):  
Systematic Review ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Prognostic Value ◽  
Meta Analysis ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Cardiac Baroreceptor Sensitivity Predicts Long-Term Outcome After Acute Ischemic Stroke

Stroke ◽  
2003 ◽  
Vol 34 (3) ◽  
pp. 705-712 ◽  
Author(s):  
Thompson G. Robinson ◽  
Suzanne L. Dawson ◽  
Penelope J. Eames ◽  
Ronney B. Panerai ◽  
John F. Potter
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Baroreceptor Sensitivity ◽  
Term Outcome ◽  
Long Term Outcome

Long-Term Outcome as Function of Blood Pressure in Acute Ischemic Stroke and Effects of Thrombolysis

2007 ◽  
Vol 24 (4) ◽  
pp. 349-354 ◽  
Author(s):  
Mei Yong ◽  
Hans-Christoph Diener ◽  
Markku Kaste ◽  
Jochen Mau
Keyword(s):  
Blood Pressure ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Term Outcome ◽  
Long Term Outcome

Association between body mass index and the effect of antihypertensive treatment on the long-term outcome of patients with acute ischemic stroke

2015 ◽  
Vol 9 (4) ◽  
pp. e122
Author(s):  
Konstantinos Tziomalos ◽  
Stella Bouziana ◽  
Marianna Spanou ◽  
Stavroula Kostaki ◽  
Maria Papadopoulou ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Body Mass ◽  
Antihypertensive Treatment ◽  
Term Outcome ◽  
Long Term Outcome

Prediction of Long-term Outcome in the Early Hours Following Acute Ischemic Stroke

1995 ◽  
Vol 52 (3) ◽  
pp. 250-255 ◽  
Author(s):  
M. Fiorelli ◽  
A. Alperovitch ◽  
C. Argentino ◽  
M. L. Sacchetti ◽  
D. Toni ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Term Outcome ◽  
Long Term Outcome
Sign in / Sign up

Export Citation Format

Share Document