scholarly journals Letter by Aries et al Regarding Article, “Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head-of-Bed Manipulation”

Stroke ◽  
2014 ◽  
Vol 45 (9) ◽  
Author(s):  
Marcel J.H. Aries ◽  
Patrick C.A.J. Vroomen ◽  
Jan Willem J. Elting
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Stroke Patients ◽  
Bedside Monitoring

scholarly journals Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head-of-Bed Manipulation

Stroke ◽  
2014 ◽  
Vol 45 (5) ◽  
pp. 1269-1274 ◽  
Author(s):  
Christopher G. Favilla ◽  
Rickson C. Mesquita ◽  
Michael Mullen ◽  
Turgut Durduran ◽  
Xiangping Lu ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Stroke Patients ◽  
Bedside Monitoring

scholarly journals Blood pressure reduction in hypertensive acute ischemic stroke patients does not affect cerebral blood flow

2018 ◽  
Vol 39 (9) ◽  
pp. 1878-1887 ◽  
Author(s):  
Mahesh Kate ◽  
Negar Asdaghi ◽  
Laura C Gioia ◽  
Brian Buck ◽  
Sumit R Majumdar ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Antihypertensive Drugs ◽  
Controlled Trial ◽  
Blood Pressure Reduction ◽  
Stroke Patients ◽  
Before And After

The effect of blood pressure (BP) reduction on cerebral blood flow (CBF) in acute ischemic stroke is unknown. We measured regional CBF with perfusion-weighted MRI before and after BP treatment in a three-armed non-randomized prospective controlled trial. Treatment arm assignment was based on acute mean arterial pressure (MAP). Patients with (MAP) >120 mmHg ( n = 14) were treated with intravenous labetalol and sublingual (SL) nitroglycerin (labetalol group). Those with MAP 100–120 mmHg ( n = 17) were treated with SL nitroglycerin (0.3 mg) (‘NTG Group’) and those with baseline MAP<100 mmHg ( n = 18) were not treated with antihypertensive drugs (untreated group). Forty-nine patients (18 female, mean age 65.3 ± 12.9 years) were serially imaged. Labetalol reduced MAP by 12.5 (5.7–17.7) mmHg, p = 0.0002. MAP remained stable in the NTG (6.0 (0.4–16, p = 0.3) mmHg and untreated groups (−0.3 (−2.3–7.0, p = 0.2) mmHg. The volume of total hypoperfused tissue (CBF<18 ml/100 g/min) did not increase after labetalol (−1.1 ((−6.5)–(−0.2)) ml, p = 0.1), NTG (0 ((−1.5)–4.5) ml, p = 0.72), or no treatment 0.25 ((−10.1)–4.5) ml, p = 0.87). Antihypertensive therapy, based on presenting BP, in acute stroke patients was not associated with an increased volume of total hypoperfused tissue.

scholarly journals Early microvascular cerebral blood flow response to head-of-bed elevation is related to outcome in acute ischemic stroke

2019 ◽  
Vol 266 (4) ◽  
pp. 990-997 ◽  
Author(s):  
Clara Gregori-Pla ◽  
Igor Blanco ◽  
Pol Camps-Renom ◽  
Peyman Zirak ◽  
Isabel Serra ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Blood Flow Response ◽  
Bed Elevation ◽  
Flow Response ◽  
Head Of Bed Elevation
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