scholarly journals Population-Based Study of Disability and Institutionalization After Transient Ischemic Attack and Stroke

Stroke ◽  
2013 ◽  
Vol 44 (10) ◽  
pp. 2854-2861 ◽  
Author(s):  
Ramon Luengo-Fernandez ◽  
Nicola L.M. Paul ◽  
Alastair M. Gray ◽  
Sarah T. Pendlebury ◽  
Linda M. Bull ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Care Home ◽  
Multivariate Regression Analysis ◽  
Population Based ◽  
Modified Rankin Scale ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome ◽  
Ischemic Attack ◽  
The Impact

Background and Purpose— Long-term outcome information after transient ischemic attack (TIA) and stroke is required to help plan and allocate care services. We evaluated the impact of TIA and stroke on disability and institutionalization over 5 years using data from a population-based study. Methods— Patients from a UK population-based cohort study (Oxford Vascular Study) were recruited from 2002 to 2007 and followed up to 2012. Patients were followed up at 1, 6, 12, 24, and 60 months postevent and assessed using the modified Rankin scale. A multivariate regression analysis was performed to assess the predictors of disability postevent. Results— A total of 748 index stroke and 440 TIA cases were studied. For patients with TIA, disability levels increased from 14% (63 of 440) premorbidly to 23% (60 of 256) at 5 years ( P =0.002), with occurrence of subsequent stroke being a major predictor of disability. For stroke survivors, the proportion disabled (modified Rankin scale >2) increased from 21% (154 of 748) premorbidly to 43% (273 of 634) at 1 month ( P <0.001), with 39% (132 of 339) of survivors disabled 5 years after stroke. Five years postevent, 70% (483 of 690) of patients with stroke and 48% (179 of 375) of patients with TIA were either dead or disabled. The 5-year risk of care home institutionalization was 11% after TIA and 19% after stroke. The average 5-year cost per institutionalized patient was $99 831 (SD, 67 020) for TIA and $125 359 (SD, 91 121) for stroke. Conclusions— Our results show that 70% of patients with stroke are either dead or disabled 5 years after the event. Thus, there remains considerable scope for improvements in acute treatment and secondary prevention to reduce postevent disability and institutionalization.

scholarly journals A Population-Based Study of Transient Ischemic Attack Incidence in Novosibirsk, Russia, 1987–1988 and 1996–1997

Stroke ◽  
2000 ◽  
Vol 31 (1) ◽  
pp. 9-13 ◽  
Author(s):  
Valery L. Feigin ◽  
Sergey V. Shishkin ◽  
Georgii M. Tzirkin ◽  
Tatyana E. Vinogradova ◽  
Alexey V. Tarasov ◽  
...  
Keyword(s):  
Transient Ischemic Attack ◽  
Population Based ◽  
Population Based Study ◽  
Ischemic Attack

scholarly journals Population-Based Study of Behavior Immediately After Transient Ischemic Attack and Minor Stroke in 1000 Consecutive Patients

Stroke ◽  
2010 ◽  
Vol 41 (6) ◽  
pp. 1108-1114 ◽  
Author(s):  
Arvind Chandratheva ◽  
Daniel S. Lasserson ◽  
Olivia C. Geraghty ◽  
Peter M. Rothwell
Keyword(s):  
Transient Ischemic Attack ◽  
Population Based ◽  
Minor Stroke ◽  
Population Based Study ◽  
Ischemic Attack

scholarly journals P137 Long-term outcome of paediatric-onset Crohn's disease: A population-based study

2012 ◽  
Vol 6 ◽  
pp. S64 ◽  
Author(s):  
A. Peneau ◽  
J. Salleron ◽  
M. Fumery ◽  
G. Savoye ◽  
E. Lerebours ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome

scholarly journals Seizures Do Not Affect Disability and Mortality Outcomes of Stroke: A Population-Based Study

2019 ◽  
Vol 8 (11) ◽  
pp. 2006 ◽  
Author(s):  
Giovanni Merlino ◽  
Gian Luigi Gigli ◽  
Francesco Bax ◽  
Anna Serafini ◽  
Elisa Corazza ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Population Based ◽  
Age Difference ◽  
Stroke Patients ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome ◽  
Cerebrovascular Accidents ◽  
Post Stroke

Although seizures are frequently seen after cerebrovascular accidents, their effects on long-term outcome in stroke patients are still unknown. Therefore, the aim of this study was to investigate the relationship between post-stroke seizures and the risk of long-term disability and mortality in stroke patients. This study is part of a larger population-based study. All patients were prospectively followed up by a face-to-face interview or a structured telephone interview. We enrolled 635 patients with first-ever stroke and without a history of seizures. Prevalence of ischemic stroke (IS) was 85.2%, while the remaining 14.8% of patients were affected by intracerebral hemorrhage (ICH). During the study period, 51 subjects (8%) developed post-stroke seizures. Patients with post-stroke seizures were younger, had a higher prevalence of ICH, had a more severe stroke at admission, were more likely to have an IS involving the total anterior circulation, and were more likely to have a lobar ICH than patients without seizures. Moreover, subjects with seizures had more frequently hemorrhagic transformation after IS and cortical strokes. At 24 months, the risk of disability in patients with seizures was almost twice than in those without seizures. However, the negative effect of seizures disappeared in multivariate analysis. Kaplan-Meier survival curves at 12 years were not significantly different between patients with and without post-stroke seizures. Using the Cox multivariate analysis, age, NIHSS at admission, and pre-stroke mRS were independently associated with all-cause long-term mortality. In our sample, seizures did not impair long-term outcome in patients affected by cerebrovascular accidents. The not significant, slight difference in favor of a better survival for patients with seizures may be attributed to the slight age difference between the two groups.

Abstract 16375: The Association Between Pregestational Hypertension and Cardiovascular Events in Pregnant Females, a Population-based Study

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Mohamed M Gad ◽  
Jasmin Abdeldayem ◽  
Devora lichtman ◽  
Islam Y Elgendy ◽  
Anas M Saad ◽  
...  
Keyword(s):  
Pregnant Women ◽  
Multivariate Regression ◽  
Nationwide Inpatient Sample ◽  
Multivariate Regression Analysis ◽  
Population Based ◽  
Cardiovascular Outcomes ◽  
P Value ◽  
Population Based Study ◽  
Pregnant Females ◽  
The Impact

Introduction: Pregestational hypertension is associated with poor fetal and maternal outcomes, however, the impact on maternal cardiovascular outcomes is not well defined. In this study, we aim to study the impact of pregestational hypertension on maternal cardiovascular outcomes. Methods: Pregnant women hospitalized from January 2016 to December 2017 were identified in the Nationwide Inpatient Sample. Pregnant females with pregestational hypertension were identified using AHRQ comorbidity measures. Outcomes of interest were mortality, myocardial infarction (MI), and stroke. Multivariate regression analysis adjusting for differences in baseline comorbidities was used for odds ratio (OR) and 95% confidence interval (CI). Results: Among 8,141,277 pregnant women, 224,295 (2.76%) had pregestational hypertension. Pregnant females with pregestational hypertension were significantly older (mean age of 31.52 +/- 6.03 vs. 28.65 +/- 5.84, p-value<0.001), and had a higher burden of comorbidities includingpregestational diabetes mellitus (10.4% vs. 1.1%, p-value<0.001), gestational diabetes (26.3% vs. 8.1%, p-value<0.001), obesity (27.6% vs. 7.7%, p-value<0.001), smoking (16.4% vs. 9.8%,p-value<0.001), hyperlipidemia (2.1% vs. 0.2%, p-value<0.001), and depression; 6.6% vs. 3.0%, p-value<0.001. Females with pregestational hypertension had more cesarean section; 46.6% vs. 29.2%, p-value<0.001, intra-uterine death; 1.3% vs. 0.4%, p-value<0.001, and spontaneous abortion; 0.6% vs. 0.3%, p-value<0.001. Pregetational hypertension had higher mortality rate (55.7 vs. 10.1 per 100,000 hospitalizations, p-value<0.001), MI rate (207.3 vs. 9.3 per 100,000 hospitalizations, p-value<0.001), and stroke rate (288.4 vs. 22.6 per 100,000 hospitalizations, p-value<0.001). Pregestational hypertension was associated with significantly worse outcomes including in-hospital mortality (aOR 3.01, 95% CI 2.48-3.67), MI (aOR 8.27, 95% CI 7.30-9.35), and stroke (aOR 9.31, 95% CI 8.47-10.24). Conclusions: Pregestational hypertension is associated with poor maternal cardiovascular outcomes in pregnancy. Further efforts should be directed to identifying high-risk females and better approaches to management are warranted.

Long-term outcome of paediatric-onset multiple sclerosis: a population-based study

2012 ◽  
Vol 84 (2) ◽  
pp. 141-147 ◽  
Author(s):  
Katharine E Harding ◽  
Kate Liang ◽  
Mark D Cossburn ◽  
Gillian Ingram ◽  
Claire L Hirst ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Population Based ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome

scholarly journals S2008 Long- Term Outcome of Treatment With Infliximab in Paediatric Crohn's Disease:a Population-Based Study

2010 ◽  
Vol 138 (5) ◽  
pp. S-300
Author(s):  
Valérie Crombé ◽  
Julia Salleron ◽  
Guillaume Savoye ◽  
Jean-Louis Dupas ◽  
Gwenola Vernier-Massouille ◽  
...  
Keyword(s):  
Population Based ◽  
Term Outcome ◽  
Population Based Study ◽  
Long Term Outcome

Renal dysfunction and chronic kidney disease in ischemic stroke and transient ischemic attack: A population-based study

2017 ◽  
Vol 12 (7) ◽  
pp. 761-769 ◽  
Author(s):  
Derek Hayden ◽  
Christine McCarthy ◽  
Layan Akijian ◽  
Elizabeth Callaly ◽  
Danielle Ní Chróinín ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Ischemic Stroke ◽  
Kidney Disease ◽  
Renal Dysfunction ◽  
Transient Ischemic Attack ◽  
Population Based ◽  
Population Based Study ◽  
Ischemic Attack

scholarly journals A Population-Based Study of Hospital Care Costs During 5 Years After Transient Ischemic Attack and Stroke

Stroke ◽  
2012 ◽  
Vol 43 (12) ◽  
pp. 3343-3351 ◽  
Author(s):  
Ramon Luengo-Fernandez ◽  
Alastair M. Gray ◽  
Peter M. Rothwell
Keyword(s):  
Transient Ischemic Attack ◽  
Hospital Care ◽  
Population Based ◽  
Population Based Study ◽  
Ischemic Attack ◽  
Care Costs
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