scholarly journals Arterial Stiffness and Cerebral Small Vessel Disease

Stroke ◽  
2012 ◽  
Vol 43 (10) ◽  
pp. 2637-2642 ◽  
Author(s):  
Mariëlle M.F. Poels ◽  
Kèren Zaccai ◽  
Germaine C. Verwoert ◽  
Meike W. Vernooij ◽  
Albert Hofman ◽  
...  
Keyword(s):  
Arterial Stiffness ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Vessel Disease

scholarly journals Arterial Stiffness Is Associated With Basal Ganglia Enlarged Perivascular Spaces and Cerebral Small Vessel Disease Load

Stroke ◽  
2018 ◽  
Vol 49 (5) ◽  
pp. 1279-1281 ◽  
Author(s):  
Iolanda Riba-Llena ◽  
Joan Jiménez-Balado ◽  
Xavier Castañé ◽  
Anna Girona ◽  
Antonio López-Rueda ◽  
...  
Keyword(s):  
Basal Ganglia ◽  
Arterial Stiffness ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Perivascular Spaces ◽  
Vessel Disease

Abstract TMP110: Arterial Stiffness And Progressive Neurological Deficit In Patients With Acute Deep Subcortical Infarction

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Naoki Saji ◽  
Kazumi Kimura ◽  
Toshitaka Kawarai ◽  
Hirotaka Shimizu ◽  
Yasushi Kita
Keyword(s):  
Arterial Stiffness ◽  
Infarct Size ◽  
Neurological Deficit ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Vessel Disease ◽  
Oscillometric Device ◽  
Progressive Neurological Deficit ◽  
Subcortical Infarction

Introduction: Deep subcortical infarction sometimes presents with progressive neurological deficit (PND). The etiology of PND is the occlusion of perforating arteries due to cerebral small vessel disease. Cerebral small vessel disease is associated with arterial stiffness, a marker of both arteriosclerosis and vascular endothelial impairment, and can cause neurological damage. Hypothesis: Arterial stiffness is independently associated with PND in patients with acute deep subcortical infarcts. Methods: Between October 2003 and March 2010, we evaluated 156 consecutive first-ever ischemic stroke patients with acute deep subcortical infarction. PND was defined as an increment of ≥2 points in the National Institute of Health Stroke Scale score or an increase of ≥1 point in the limb weakness score within seven days of stroke onset. Patients were assessed for risk factors, and infarct size was measured on initial diffusion-weighted magnetic resonance imaging (DWI). We measured brachial-ankle pulse wave velocity (baPWV) as a marker of arterial stiffness using an oscillometric device (Form PWV/ABI®; Omron Colin Co., Ltd., Tokyo, Japan). We divided patients into two groups according to the presence or absence of PND to compare their clinical characteristics. Results: Fifty-two patients (33%) had PND, and baPWV was significantly higher in patients with than without PND. The baPWV cutoff value for PND was 18.24 m/s, with 90% sensitivity and 47% specificity. In multivariable logistic regression analysis, high baPWV [≥18.24 m/s, odds ratio (OR) 8.22, 95% confidence interval (95% CI) 2.55-31.9], large infarct size (≥15 mm, OR 2.76, 95% CI 1.01-7.92) and ≥3 infarct slices on serial axial DWI (OR 3.38, 95% CI 1.22-10.0) were independently associated with PND. Conclusions: Arterial stiffness indicated by baPWV is independently associated with PND in patients with acute deep subcortical infarction.

scholarly journals Cerebral Small Vessel Disease and Arterial Stiffness: Tsunami Effect in the Brain?

Pulse ◽  
2016 ◽  
Vol 3 (3-4) ◽  
pp. 182-189 ◽  
Author(s):  
Naoki Saji ◽  
Kenji Toba ◽  
Takashi Sakurai
Keyword(s):  
Arterial Stiffness ◽  
Small Vessel Disease ◽  
Cerebral Small Vessel Disease ◽  
Small Vessel ◽  
Vessel Disease ◽  
The Brain
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