scholarly journals Metabolic Syndrome and the Risk of Ischemic Heart Disease and Stroke Among Japanese Men and Women

Stroke ◽  
2007 ◽  
Vol 38 (6) ◽  
pp. 1744-1751 ◽  
Author(s):  
Hiroyasu Iso ◽  
Shinichi Sato ◽  
Akihiko Kitamura ◽  
Hironori Imano ◽  
Masahiko Kiyama ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Japanese Men ◽  
Men And Women

scholarly journals Peanut Consumption and Risk of Stroke and Ischemic Heart Disease in Japanese Men and Women: The JPHC Study

Stroke ◽  
2021 ◽  
Author(s):  
Satoyo Ikehara ◽  
Hiroyasu Iso ◽  
Yoshihiro Kokubo ◽  
Kazumasa Yamagishi ◽  
Isao Saito ◽  
...  
Keyword(s):  
Public Health ◽  
Cardiovascular Disease ◽  
Heart Disease ◽  
Ischemic Stroke ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Japanese Men ◽  
Food Frequency ◽  
Men And Women ◽  
History Of

Background and Purpose: Several prospective cohort studies and a randomized clinical trial have shown the beneficial effects of peanut consumption on cardiovascular disease and its risk factors. We examined the association between peanut consumption and risk of cardiovascular disease in Japanese men and women. Methods: We analyzed data of 74 793 participants aged 45 to 74 years who completed a lifestyle questionnaire including the validated food frequency questionnaire in the Japan Public Health Center–based Prospective Study. They were followed up from 1995 to 2009 for cohort I and from 1998 to 1999 to 2012 for cohort II. Peanut consumption was calculated from the food frequency questionnaire, and the end points were incidence of stroke, ischemic heart disease, and cardiovascular disease (stroke and ischemic heart disease). Results: During a median follow-up of 14.8 years, 3,599 strokes and 849 ischemic heart diseases were reported. Higher peanut consumption was associated with reduced risks of total stroke, ischemic stroke, and cardiovascular disease among men and women. The multivariable hazard ratios (95% CIs) for the highest versus lowest quartiles of peanut consumption after adjustment for age, sex, public health center, smoking, alcohol consumption, perceived stress level, physical activity, vegetable, fruit, fish, soy, sodium and total energy intakes, body mass index, history of hypertension, history of diabetes, and cholesterol-lowering drug were 0.84 (0.77–0.93, P for trend=0.002) for total stroke, 0.80 (0.71–0.90, P for trend=0.002) for ischemic stroke, 0.93 (0.79–1.08, P for trend=0.27) for hemorrhagic stroke, 0.97 (0.80–1.17, P for trend=0.81) for ischemic heart disease and 0.87 (0.80–0.94, P for trend=0.004) for cardiovascular disease, and these associations were similarly observed in both sexes. Conclusions: Higher peanut consumption was associated with reduced risk of stroke, especially ischemic stroke, but not ischemic heart disease in Japanese men and women.

scholarly journals Association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons

Medicina ◽  
2008 ◽  
Vol 44 (5) ◽  
pp. 392 ◽  
Author(s):  
Liucija Černiauskienė ◽  
Dalia Lukšienė ◽  
Abdonas Tamošiūnas ◽  
Regina Rėklaitienė ◽  
Lilija Margevičienė
Keyword(s):  
Oxidative Stress ◽  
Metabolic Syndrome ◽  
Heart Disease ◽  
Vitamin E ◽  
Ischemic Heart Disease ◽  
Odds Ratio ◽  
Ischemic Heart ◽  
Middle Aged ◽  
Men And Women ◽  
And Oxidative Stress

The aim of this study was to evaluate the association of metabolic syndrome and oxidative stress with ischemic heart disease in middle-aged persons (men and women aged 45–64 years). Material and methods. In this study, we have used data of 533 persons (247 men and 286 women) aged 45– 64 years from Kaunas population cohort investigated according to WHO MONICA study protocol during 2001–2002 in whom concentrations of malondialdehyde, a marker of lipid peroxidation, and antioxidant vitamin E in blood serum were determined. Metabolic syndrome was defined by the criteria of Adult Treatment Panel III. Oxidative stress was determined in the presence of increased level of malondialdehyde (≥5 mmol/L) and decreased level of lipid-standardized vitamin E (<20 mmol/L). The levels of malondialdehyde and vitamin E were measured by fluorimetric methods. Results. Ischemic heart disease was diagnosed in 19.8% of men and 21.3% of women. The frequency of ischemic heart disease among persons (men and women) with metabolic syndrome was significantly higher than among persons without metabolic syndrome (27.4% vs. 17.8%, respectively; odds ratio, 1.63; P=0.032). The frequency of ischemic heart disease among persons with oxidative stress was significantly higher than among persons without oxidative stress (29.1% vs. 17.6%, respectively; odds ratio, 1.88; P=0.029). The highest prevalence of ischemic heart disease (30.0%) was among persons with metabolic syndrome and oxidative stress, and the lowest prevalence of this disease (13.8%) was among persons without metabolic syndrome and without oxidative stress (odds ratio, 2.54; P=0.017). These data were adjusted by sex and age. Conclusion. Metabolic syndrome and oxidative stress are significantly associated with ischemic heart disease among 45–64-year-old persons.

Nonfasting serum triglycerides and risk of ischemic heart disease among Japanese men and women

2004 ◽  
Vol 1262 ◽  
pp. 200-202
Author(s):  
Hiroyasu Iso ◽  
Akihiko Kitamura ◽  
Shinichi Sato ◽  
Yoshihiko Naito ◽  
Noriyuki Imano ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Serum Triglycerides ◽  
Japanese Men ◽  
Men And Women

Metabolic Syndrome and Ischemic Heart Disease in Elderly Men and Women

2001 ◽  
Vol 153 (5) ◽  
pp. 481-489 ◽  
Author(s):  
Ulf Lindblad ◽  
Robert D. Langer ◽  
Deborah L. Wingard ◽  
Ronald G. Thomas ◽  
Elizabeth L. Barrett-Connor
Keyword(s):  
Metabolic Syndrome ◽  
Heart Disease ◽  
Ischemic Heart Disease ◽  
Ischemic Heart ◽  
Elderly Men ◽  
Men And Women
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