scholarly journals Relationship Between Nonsustained Ventricular Tachycardia After Non–ST-Elevation Acute Coronary Syndrome and Sudden Cardiac Death

Circulation ◽  
2010 ◽  
Vol 122 (5) ◽  
pp. 455-462 ◽  
Author(s):  
Benjamin M. Scirica ◽  
Eugene Braunwald ◽  
Luiz Belardinelli ◽  
Chester M. Hedgepeth ◽  
Jindrich Spinar ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Ventricular Tachycardia ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Nonsustained Ventricular Tachycardia ◽  
Coronary Syndrome ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

scholarly journals The risk of sudden cardiac death in patients with non-ST elevation acute coronary syndrome and prolonged QTc interval: effect of ranolazine

EP Europace ◽  
2012 ◽  
Vol 15 (3) ◽  
pp. 429-436 ◽  
Author(s):  
Ewa Karwatowska-Prokopczuk ◽  
Whedy Wang ◽  
Mei L. Cheng ◽  
Dewan Zeng ◽  
Peter J. Schwartz ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Qtc Interval ◽  
Coronary Syndrome ◽  
Interval Effect ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

Extreme QT Interval Prolongation and Helicoid Ventricular Tachycardia (Torsade de Pointes) in Non-ST-Elevation Acute Coronary Syndrome

2012 ◽  
Vol 65 (3) ◽  
pp. 294-296
Author(s):  
Montse Vilaseca-Corbera ◽  
Gabriel Vázquez-Oliva ◽  
Cristina Campoamor-Cela ◽  
Alberto Zamora-Cervantes ◽  
Joan Bassanyanes-Vilarrasa ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Ventricular Tachycardia ◽  
Qt Interval ◽  
Torsade De Pointes ◽  
Interval Prolongation ◽  
Coronary Syndrome ◽  
Qt Interval Prolongation ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

scholarly journals Plasma Omega‐3 Fatty Acids and the Risk of Cardiovascular Events in Patients After an Acute Coronary Syndrome in MERLIN‐TIMI 36

2021 ◽  
Author(s):  
Thomas A. Zelniker ◽  
David A. Morrow ◽  
Benjamin M. Scirica ◽  
Jeremy D. Furtado ◽  
Jianping Guo ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Acute Coronary Syndrome ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
Cardiovascular Death ◽  
Omega 3 ◽  
Lower Odds ◽  
Coronary Syndrome ◽  
Elevation Acute Coronary Syndrome ◽  
Long Chain

Background Plasma omega‐3 polyunsaturated fatty acids (ω3‐PUFAs) have been shown to be inversely correlated with the risk of cardiovascular death in primary prevention. The risk relationship in the setting of an acute coronary syndrome is less well established. Methods and Results Baseline plasma ω3‐PUFA composition (α‐linolenic acid, eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid) was assessed through gas chromatography with flame ionization detection in a case‐cohort study involving 203 patients with cardiovascular death, 325 with myocardial infarction, 271 with ventricular tachycardia, and 161 with atrial fibrillation, and a random sample of 1612 event‐free subjects as controls from MERLIN‐TIMI 36 (Metabolic Efficiency With Ranolazine for Less Ischemia in Non–ST‐Elevation‐Acute Coronary Syndrome–Thrombolysis in Myocardial Infarction 36), a trial of patients hospitalized with non–ST‐segment–elevation ‐acute coronary syndrome. After inverse‐probability‐weighted multivariable adjustment including all traditional risk factors, a higher relative proportion of long‐chain ω3‐PUFAs (eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid) were associated with 18% lower odds of cardiovascular death (adjusted [adj] odds ratio [OR] per 1 SD, 0.82; 95% CI, 0.68–0.98) that was primarily driven by 27% lower odds of sudden cardiac death (adj OR per 1 SD, 0.73; 95% CI, 0.55–0.97). Long‐chain ω3‐PUFA levels in the top quartile were associated with 51% lower odds of cardiovascular death (adj OR 0.49; 95% CI, 0.27–0.86) and 63% lower odds of sudden cardiac death (adj OR, 0.37; 95% CI, 0.16–0.56). An attenuated relationship was seen for α‐linolenic acid and subsequent odds of cardiovascular (adj OR, 0.92; 95% CI, 0.74–1.14) and sudden cardiac death (adj OR, 0.91; 95% CI, 0.67–1.25). No significant relationship was observed between any ω3‐PUFAs and the odds of cardiovascular death unrelated to sudden cardiac death, myocardial infarction, atrial fibrillation, or early post‐acute coronary syndrome ventricular tachycardia. Conclusions In patients after non–ST‐segment–elevation‐acute coronary syndrome, plasma long‐chain ω3‐PUFAs are inversely associated with lower odds of sudden cardiac death, independent of traditional risk factors and lipids. Registration URL: https://www.clinicaltrials.gov . Unique identifier: NCT00099788.

scholarly journals Sudden Cardiac Death After Non–ST-Segment Elevation Acute Coronary Syndrome

2016 ◽  
Vol 1 (1) ◽  
pp. 73 ◽  
Author(s):  
Paul L. Hess ◽  
Daniel M. Wojdyla ◽  
Sana M. Al-Khatib ◽  
Yuliya Lokhnygina ◽  
Lars Wallentin ◽  
...  
Keyword(s):  
Acute Coronary Syndrome ◽  
Sudden Cardiac Death ◽  
Cardiac Death ◽  
St Segment Elevation ◽  
Coronary Syndrome ◽  
St Segment ◽  
Elevation Acute Coronary Syndrome
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