Abstract 18: Seasonal Characteristic Of Kawasaki Disease With The Onset At The Different Seasons

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Yukie Ozeki ◽  
Fumiya Yamada ◽  
Tsuyoshi Kishimoto ◽  
Yosikazu Nakamura
Keyword(s):  
Kawasaki Disease ◽  
Serum Albumin ◽  
Epidemiologic Study ◽  
Seasonal Trend ◽  
Albumin Concentration ◽  
Female Ratio ◽  
Number Of Patients ◽  
Different Seasons ◽  
Patient Groups ◽  
The Difference

Background: Kawasaki disease (KD) has been diagnosed in more than 60 countries. Seasonal trend of the patients with KD is observed in many countries. Little is known about the difference between the patient groups in the term of high incidence. Objective: The aim of this study was to characterize the two patient groups during the winter and summer seasons in Japan. Methods: Epidemiologic characteristics were compared between January and July, through the 22th nationwide survey included patients who visited hospitals during 2011-2012. The proportions of survey items were observed by age-adjustment. Results: The total number of patients during 2011-12 was 26,691, the number of patients was 2812 in January and 2302 in July, and the male/female ratio was 1.4, respectively. The patients <3 years account for 66% of each group (1854/2812, 1530/2302). The proportion of <8 months of age was 13.0% (365/2812) in January, 17.8% (409/2302) in July, that of 15 months to 3 years was 38.8% (1092/2812), and 33.5% (771/2302). Concurrence with the diagnostic guidelines was examined, the typical cases in July were 1.6% lower than in January, and the suspected cases were 1.3% higher than in January. The suspected cases of less than 4 principle symptoms had 5.3% higher than in January. The treatment cases with γ-globulin started within 5 days of illness were 2.2% less than in July. The cases of cardiac sequelae (giant aneurysm, aneurysm, dilatation, and stenosis) were 0.3% higher than in July. The cases of serum albumin concentration less than 3.2g/dL were 3.6% higher than in July. The percentage of occurrence cardiac sequelae in this class was 9.5% higher than in July. Discussion: The difference in age distribution in the two patient groups diagnosed in January and July was observed. The symptom had a slight difference, too. These result do not contradict a hypothesis that onset of KD is concerned with plural infections with different seasonal trend and targeting for the specific age. The association between low levels of serum albumin and cardiac sequelae has been known. The association between this class and the patients in the specific season will be clear in future epidemiologic study. Conclusion: This study clarified part of the characteristic of the patient diagnosed in the different seasons.

Interpretation of cerebrospinal fluid protein assays in various neurologic diseases.

1983 ◽  
Vol 29 (6) ◽  
pp. 1028-1030 ◽  
Author(s):  
R H Christenson ◽  
P Behlmer ◽  
J F Howard ◽  
J B Winfield ◽  
L M Silverman
Keyword(s):  
Cerebrospinal Fluid ◽  
Serum Albumin ◽  
Lupus Erythematosus ◽  
Calculated Data ◽  
Albumin Concentration ◽  
Sarcoidosis Patient ◽  
Igg Index ◽  
Oligoclonal Banding ◽  
Patient Groups ◽  
Protein Assays

Abstract Albumin and immunoglobulin G (IgG) were determined in cerebrospinal fluid (CSF) and serum, and the CSF/serum albumin Index (CSF X 10(3)/serum albumin concentration ratio) and IgG Index [(CSF/serum IgG)/(CSF/serum albumin)] were calculated. Data for these indices and oligoclonal banding are described in 23 cases of multiple sclerosis (MS), 19 of systemic lupus erythematosus (SLE), eight of sarcoidosis, 48 cases of miscellaneous disease, and 25 control patients with nonspecific complaints. Of the MS, SLE, and sarcoidosis patient groups, 8.5%, 26%, and 12.5% showed an abnormally high CSF/serum albumin Index; 87%, 16%, and 0% an increased IgG Index; and 87.5%, 42% and 0% showed positive oligoclonal banding. IgG Index and oligoclonal banding results for MS patients differed significantly from the sarcoidosis (p less than .001) and SLE (p less than .05) groups. When the CSF/serum albumin Index is considered also, the control and sarcoidosis patient results differ significantly from the MS group (p less than .001 and p less than .01). A strong correlation between the IgG Index and oligoclonal banding is implicated.

Epidemiologic Pictures of Kawasaki Disease in Japan: From the Nationwide Incidence Survey in 1991 and 1992

PEDIATRICS ◽  
1995 ◽  
Vol 95 (4) ◽  
pp. 475-479 ◽  
Author(s):  
Hiroshi Yanagawa ◽  
Mayumi Yashiro ◽  
Yosikazu Nakamura ◽  
Tomisaku Kawasaki ◽  
Hirohisa Kato
Keyword(s):  
Kawasaki Disease ◽  
Disease Onset ◽  
Incidence Rates ◽  
Descriptive Epidemiology ◽  
Female Ratio ◽  
Number Of Patients ◽  
Yearly Incidence ◽  
Male Female Ratio ◽  
History Of ◽  
Questionnaire Form

Objective. Since 1970, twelve nationwide epidemiologic surveys of Kawasaki disease (KD) have been conducted throughout Japan every two years to describe KD in Japan. By the end of 1992, a total of 116 848 cases were reported. This paper summarizes the statistical analysis of the latest survey for the 2-year period from January 1991 through December 1992. Method. A questionnaire form and diagnostic guidelines for KD were sent to all pediatric departments of hospitals with 100 or more beds throughout Japan and information was obtained on patients with KD diagnosed during the 2-year period from January 1991 through December 1992. Results. The summary of the results is: 1) the number of patients reported was 11 221 (6604 males and 4617 females; male/female ratio = 1.43) with a yearly incidence rate of 90 per 100 000 children &lt;5 years old; 2) the monthly number of patients was higher in winter and summer, although the monthly difference was not marked; 3) age-specific incidence rates showed a unimodal peak at 1 year of age; 4) the proportion of patients with a family history of KD in a sibling was 1%; 5) the proportion of recurrent patients was 3%; 6) the proportion of patients with cardiac sequelae 1 month after disease onset was 13%; and 7) the number of patients who died was 9, which conforms to 0.08% of total patients. Conclusion. The incidence rates of KD in Japan are ten times higher than those reported in western countries and almost constant over 6 years. The descriptive epidemiology of the disease, which supports the infection theory, does not change for years.

scholarly journals A comparison of the effect of breast feeding, mixed feeding and top feeding on weights of infants and children

2016 ◽  
Vol 10 (2) ◽  
Author(s):  
Bushra Karim Javed ◽  
Samina Karim ◽  
Ghulam Rasool ◽  
Iftikhar , ◽  
Yaqoob Kazi
Keyword(s):  
Retrospective Analysis ◽  
Breast Feeding ◽  
P Value ◽  
Mixed Feeding ◽  
Female Ratio ◽  
Exclusive Breast Feeding ◽  
Number Of Patients ◽  
The Difference ◽  
Male To Female ◽  
Breast Fed

A retrospective analysis of 503 patients admitted to diarrhoea ward between June to August 2003 was done regarding their weight and feeding practices. Out of them 36 children were excluded as they did not full fill the required criteria. So a total of 467 patients were studied. The patients were divided into three groups depending upon whether they were breast fed, mixed i.e. both breast and top fed, or top fed respectively. All patients between the ages of birth and 24 months were included. The number of patients in breast fed, mixed fed and top fed were 134,135 and 198 respectively. Male to female ratio was 1.4:1,1.5:1,1.4:1,with mean age in breast fed group for females 6.9± 4.7 months and males 10.3±7.63,in mixed fed group 8.3± 5.97 months and 8.4 ± 6.4 months and in top fed group 8.25±7.35 months and 7.65 ±5.72 months respectively. Mean weight in each group was 6.1±1.9, 5.7 ± 2.1 and 4.9±2.0 kg. When weight of breast fed children was compared with those of mixed fed the difference was not statistically significant with p value of 0.236 while the comparison with top fed was highly significant with p value of 0.000. Similarly babies on mixed feeding had significantly better weight than that of top fed with p value of 0.004. Although it has been stressed upon and a lot of effort has been put in to encourage breast feeding but still top feeding and mixed feeding are on the top resulting in malnourished and wasted children. From our study it is obvious that top fed children are grossly malnourished, and exclusive breast feeding is low. We need to take more steps to encourage breast feeding.

scholarly journals Comparison of marginal adaptation of fiber reinforced composite and metal ceramic full veneer crown

2015 ◽  
Vol 5 (1) ◽  
pp. 1-5
Author(s):  
Tareq Hassan ◽  
Sohana Ferdous ◽  
Aslam Md Aurangjeb
Keyword(s):  
Marginal Adaptation ◽  
Fiber Reinforced ◽  
Female Ratio ◽  
Fiber Reinforced Composite ◽  
Reinforced Composite ◽  
Number Of Patients ◽  
Metal Ceramic ◽  
Group A ◽  
The Difference ◽  
Group B

Fiber reinforcement was introduced to clinical dentistry for the first time in the 1960s when investigators attempted to reinforce polymethyl-methacrylate dentures with glass or carbon fibers. It has recently been shown that crowns, bridges and posts made of FRC can be used successfully in dental practice and on the basis of marginal adaptation they are more acceptable than conventional metal ceramic crown. A prospective comparative cross-sectional study was performed involving 60 patients who attended in the out patients department of Prosthodontics, Faculty of Dentistry, BSMMU during the period of January 2007 to December 2008. Clinical data were recorded for the selected 60 patients who were divided into two groups “experimental” and “control”. Marginal adaptation was indexed after California Dental Associations quality evaluation system. The age of the patients ranged from 18 to 42 years in group A and 17 to 38 years in group B. The highest number of patients was in the age group 21-30 years in both the groups. The mean age was 24.9±5.8 years and 25.0±4.8 years in group A and group B respectively. There were 26 male and 34 female patients in the study and male female ratio was 1:1.3. In group A patients, 12(40.0%) were male and 18(60.0%) female. In group B patients 14(46.7%) were male and 16(53.3%) were female. After 4 months all the patients were in grade I in both the groups. After 8 months all the patients were in grade I in group A and 27(90.0%) patients in grade I in group B.  After 12 months all the patients were in grade I in group A and 25(83.3%) patients were in grade I in group B. The difference was not statistically significant (p>0.05) after 8 months, however after 12 months the difference was significant (p<0.05). The Fiber Reinforced Composite crown represents a valuable development in the field of Prosthetic Dentistry. DOI: http://dx.doi.org/10.3329/bjdre.v5i1.22450 Bangladesh Journal of Dental Research and Education Vol.5(1) 2015: 01-05

scholarly journals A Prospective Study to Correlate Preoperative Serum Albumin as a Predictor of Post-Operative Mortality and Morbidity

2021 ◽  
Vol 10 (18) ◽  
pp. 1291-1295
Author(s):  
Sagar Dilip Rathod ◽  
Dhirendra D. Wagh
Keyword(s):  
Clinical Outcome ◽  
Serum Albumin ◽  
Postoperative Mortality ◽  
Postoperative Outcome ◽  
Major Surgery ◽  
Albumin Concentration ◽  
Mortality And Morbidity ◽  
Male Predominance ◽  
Preoperative Serum ◽  
Number Of Patients

BACKGROUND In recent times serum albumin has been considered as a very important factor in determining the clinical outcome of a patient undergoing major surgery. Patients with low serum albumin pre-operatively have been encountered with poor outcome postoperatively. This study was conducted to assess the association between serum albumin concentration and postoperative outcome (morbidity / mortality). METHODS This prospective observational study was carried out in JNMC and AVBRH, Sawangi, Wardha, from September 2018 to September 2020. All patients undergoing emergency / elective major surgeries were included in the study. Detailed history of patients was recorded including chief complaints and any other previous medical history. RESULTS 104 patients were included in the study of which maximum number of patients were seen in the age range of 35 – 64 years. The mean age being 48.19 ± 15.60 years. The gender distribution with more male predominance with 59.62 % participants being males and 40.38 % participants being females. Total 68 patients had postoperative complications, 40 being males and 28 being females. Highest number of complications in this study were seen in age group 55 - 64 years. 50 out of 73 patients with benign diseases developed complications and 18 out of 31 patients with malignant diseases developed complications. CONCLUSIONS Serum albumin has become an important modality to define the clinical outcome of a patient. Surgeons have started using it as a marker to define the post-operative outcome of a patient undergoing surgery. Exogenous albumin administration has also showed promising results in improving the outcome of a patient in the post-operative period. KEY WORDS Hypoalbuminaemia, Serum Albumin, Postoperative Mortality, Postoperative Morbidity

Nationwide Survey on Kawasaki Disease in Japan

PEDIATRICS ◽  
1987 ◽  
Vol 80 (1) ◽  
pp. 58-62 ◽  
Author(s):  
Hiroshi Yanagawa ◽  
Tomisaku Kawasaki ◽  
Itsuzo Shigematsu
Keyword(s):  
Statistical Analysis ◽  
Kawasaki Disease ◽  
Incidence Rate ◽  
Disease Onset ◽  
Nationwide Survey ◽  
Cumulative Number ◽  
Female Ratio ◽  
Number Of Patients ◽  
Male To Female ◽  
Sibling Cases

Results of the statistical analysis of a nationwide survey of patients with Kawasaki disease diagnosed within a 2-year 6-month period, from July 1982 to December 1984, are as follows. (1) The cumulative number of patients reported by the end of 1984 was 63,399 (36,891 boys and 26,508 girls; male to female ratio 1.4). (2) There were two epidemic years, 1979 and 1982, in which the numbers of patients were more than twofold that of the previous years. (3) A curve plotted for age-specific incidence rate showed a unimodal peak at age 1 year. (4) Steroid therapy was used for 6.3% of the patients, aspirin for 89.8%, antibiotics for 57.6%, and γ-globulin for 11.4%. (5) The proportion of sibling cases was 1.4% and that of recurrent cases was 3.9% of all cases reported. (6) The incidence of cardiac sequelae in 1 month after disease onset was 17.2%.

scholarly journals Routine clinical care data from thirteen cardiac outpatient clinics: design of the Cardiology Centers of the Netherlands (CCN) database

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Sophie H. Bots ◽  
Klaske R. Siegersma ◽  
N. Charlotte Onland-Moret ◽  
Folkert W. Asselbergs ◽  
G. Aernout Somsen ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Practitioner ◽  
Data Collection ◽  
The Netherlands ◽  
Strong Base ◽  
Daily Care ◽  
Cardiac Symptoms ◽  
Number Of Patients ◽  
Patient Groups

Abstract Background Despite the increasing availability of clinical data due to the digitalisation of healthcare systems, data often remain inaccessible due to the diversity of data collection systems. In the Netherlands, Cardiology Centers of the Netherlands (CCN) introduced “one-stop shop” diagnostic clinics for patients suspected of cardiac disease by their general practitioner. All CCN clinics use the same data collection system and standardised protocol, creating a large regular care database. This database can be used to describe referral practices, evaluate risk factors for cardiovascular disease (CVD) in important patient subgroups, and develop prediction models for use in daily care. Construction and content The current database contains data on all patients who underwent a cardiac workup in one of the 13 CCN clinics between 2007 and February 2018 (n = 109,151, 51.9% women). Data were pseudonymised and contain information on anthropometrics, cardiac symptoms, risk factors, comorbidities, cardiovascular and family history, standard blood laboratory measurements, transthoracic echocardiography, electrocardiography in rest and during exercise, and medication use. Clinical follow-up is based on medical need and consisted of either a repeat visit at CCN (43.8%) or referral for an external procedure in a hospital (16.5%). Passive follow-up via linkage to national mortality registers is available for 95% of the database. Utility and discussion The CCN database provides a strong base for research into historically underrepresented patient groups due to the large number of patients and the lack of in- and exclusion criteria. It also enables the development of artificial intelligence-based decision support tools. Its contemporary nature allows for comparison of daily care with the current guidelines and protocols. Missing data is an inherent limitation, as the cardiologist could deviate from standardised protocols when clinically indicated. Conclusion The CCN database offers the opportunity to conduct research in a unique population referred from the general practitioner to the cardiologist for diagnostic workup. This, in combination with its large size, the representation of historically underrepresented patient groups and contemporary nature makes it a valuable tool for expanding our knowledge of cardiovascular diseases. Trial registration: Not applicable.

Planning for End of Life

2021 ◽  
pp. 104990912110141
Author(s):  
Natasha Ansari ◽  
Eric Johnson ◽  
Jennifer A. Sinnott ◽  
Sikandar Ansari
Keyword(s):  
End Of Life ◽  
Treatment Options ◽  
Stage Iv ◽  
P Value ◽  
Life Planning ◽  
Number Of Patients ◽  
End Of Life Planning ◽  
The Difference ◽  
Alternative Medications ◽  
Patient’S Perception

Background: Oncology provider discussions of treatment options, outcomes of treatment, and end of life planning are essential to care for patients with advanced malignancies. Studies have shown that despite this, many patients do not have adequate care planning, including end of life planning. It is thought that the accessibility of information outside of clinical encounters and individual factors and/or beliefs may influence the patient’s perception of disease. Aims: The objective of this study was to evaluate if patient understanding of treatment goals matched the provider and if there were areas of discrepancy. If a discrepancy was found, the survey inquired further into more specific aspects. Methods: A questionnaire-based survey was performed at a cancer hospital outpatient clinic. 100 consecutive and consenting patients who had stage IV non-curable lung, gastrointestinal (GI), or other cancer were included in the study. Patients must have had at least 2 visits with their oncologist. Results: 40 patients reported their disease might be curable and 60 reported their disease was not curable. Patients who reported their disease was not curable were more likely to be 65 years or older (P-value: 0.055). They were more likely to report that their doctor discussed the possibility of their cancer getting worse (78.3% VS 55%; P-value 0.024), that their doctor discussed end of life plans (58.3% VS 30%; P- value: 0.01), and that they had appointed a health care decision-maker (86.7% VS 62.5%; P-value: 0.01). 65% of patients who thought their disease might be curable reported that their doctor said it might be curable, compared with only 6.7% of patients who thought their disease was not curable (p < 0.001). Or, equivalently, 35% of patients who thought their disease might be curable reported that their doctor’s opinion was that it was not curable, compared with 93% of patients who thought their disease was not curable (p < 0.001). Patients who had lung cancer were more likely to believe their cancer was not curable than patients with gastrointestinal or other cancer, though the difference was not statistically significant (p = 0.165). Patients who said their disease might be curable selected as possible reasons that a miracle (50%) or alternative medicine (66.7%) would get rid of the cancer, or said their family wanted them to believe the cancer would go away (16.7%) or that another doctor said it would (4.2%). Patients who said their disease might be curable said they did so due to alternative medications, another doctor, or their family. Restricting to the 70 patients who reported their doctors telling them their disease was not curable, 20% of them still said that they personally felt their disease might be curable. Patients below 65 years of age were more likely to disagree with the doctor in this case (P-value: 0.047). Conclusion: This survey of patients diagnosed with stage IV cancer shows that a significant number of patients had misunderstandings of the treatment and curability of their disease. Findings suggest that a notable proportion kept these beliefs even after being told by treating physicians that their disease is not curable.

scholarly journals Home Mechanical Ventilation: A Patient’s Perspective Survey Study

2021 ◽  
Vol 18 (8) ◽  
pp. 4048
Author(s):  
Magdalena Kwiatosz-Muc ◽  
Bożena Kopacz
Keyword(s):  
Health Care ◽  
Mechanical Ventilation ◽  
Alternative Methods ◽  
Survey Study ◽  
Home Mechanical Ventilation ◽  
Patient’S Satisfaction ◽  
Satisfaction Index ◽  
Number Of Patients ◽  
The Difference

Background: An increasing number of patients included in home mechanical ventilation (HMV) care has been under observation for many years. The study aimed to assess the patients opinion concerning the expected and perceived quality of care in an HMV system and a patient’s satisfaction with care. Methods: In 2017, patients treated with HMV were surveyed in Poland with the modified SERVQUAL questionnaire. Results: One hundred correctly completed surveys were analyzed. Patient Satisfaction Index was high. In every examined area, the expectations were statistically significant larger than the perception of the services. The biggest gap was in the tangibility dimension and the smallest gap was in the empathy dimension. Perceived respect and understanding for a patient’s needs are close to the expectations. Conclusions: The level of satisfaction with health care among patients treated with HMV in majority of investigated components is high. Moreover, the difference between perceived and expected quality of health care in the HMV system was relatively small in the opinion of the patients themselves. Further investigations with alternative methods are needed.

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