Peroxisome Proliferator–Activated Receptor δ Agonist GW1516 Attenuates Diet-Induced Aortic Inflammation, Insulin Resistance, and Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

Lazar A. Bojic; Amy C. Burke; Sanjiv S. Chhoker; Dawn E. Telford; Brian G. Sutherland; Jane Y. Edwards; Cynthia G. Sawyez; Rommel G. Tirona; Hao Yin; J. Geoffrey Pickering; Murray W. Huff

doi:10.1161/atvbaha.113.301830

Peroxisome Proliferator–Activated Receptor δ Agonist GW1516 Attenuates Diet-Induced Aortic Inflammation, Insulin Resistance, and Atherosclerosis in Low-Density Lipoprotein Receptor Knockout Mice

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.113.301830 ◽

2014 ◽

Vol 34 (1) ◽

pp. 52-60 ◽

Cited By ~ 32

Author(s):

Lazar A. Bojic ◽

Amy C. Burke ◽

Sanjiv S. Chhoker ◽

Dawn E. Telford ◽

Brian G. Sutherland ◽

...

Keyword(s):

Insulin Resistance ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Peroxisome Proliferator-activated Receptor γ Agonist Rosiglitazone Increases Expression of Very Low Density Lipoprotein Receptor Gene in Adipocytes

Journal of Biological Chemistry ◽

10.1074/jbc.m109.047993 ◽

2009 ◽

Vol 284 (44) ◽

pp. 30049-30057 ◽

Cited By ~ 25

Author(s):

Takeshi Takazawa ◽

Toshimasa Yamauchi ◽

Atsushi Tsuchida ◽

Makoto Takata ◽

Yusuke Hada ◽

...

Keyword(s):

Receptor Gene ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Peroxisome Proliferator-activated Receptor γ Activation by Ligands and Dephosphorylation Induces Proprotein Convertase Subtilisin Kexin Type 9 and Low Density Lipoprotein Receptor Expression

Journal of Biological Chemistry ◽

10.1074/jbc.m112.350181 ◽

2012 ◽

Vol 287 (28) ◽

pp. 23667-23677 ◽

Cited By ~ 43

Author(s):

Yajun Duan ◽

Yuanli Chen ◽

Wenquan Hu ◽

Xiaoju Li ◽

Xiaoxiao Yang ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Receptor Expression ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Proprotein Convertase ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Tesaglitazar, a dual peroxisome proliferator-activated receptor alpha/gamma agonist, reduces atherosclerosis in female low density lipoprotein receptor deficient mice

Atherosclerosis ◽

10.1016/j.atherosclerosis.2006.12.012 ◽

2007 ◽

Vol 195 (1) ◽

pp. 100-109 ◽

Cited By ~ 24

Author(s):

Ebele C. Chira ◽

Timothy S. McMillen ◽

Shari Wang ◽

Antonio Haw ◽

Kevin D. O’Brien ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Receptor Alpha ◽

Density Lipoprotein Receptor ◽

Deficient Mice

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Macrophage Expression of Peroxisome Proliferator–Activated Receptor-α Reduces Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

Circulation ◽

10.1161/circulationaha.106.684704 ◽

2007 ◽

Vol 116 (12) ◽

pp. 1404-1412 ◽

Cited By ~ 52

Author(s):

Vladimir R. Babaev ◽

Hiroyuki Ishiguro ◽

Lei Ding ◽

Patricia G. Yancey ◽

Dwayne E. Dove ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor ◽

Deficient Mice

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Macrophage Mal1 Deficiency Suppresses Atherosclerosis in Low-Density Lipoprotein Receptor–Null Mice by Activating Peroxisome Proliferator-Activated Receptor-γ–Regulated Genes

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.111.225839 ◽

2011 ◽

Vol 31 (6) ◽

pp. 1283-1290 ◽

Cited By ~ 32

Author(s):

Vladimir R. Babaev ◽

Robert P. Runner ◽

Daping Fan ◽

Lei Ding ◽

Youmin Zhang ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Sterol-independent repression of low density lipoprotein receptor promoter by peroxisome proliferator activated receptor γ coactivator-1α (PGC-1α)

Experimental & Molecular Medicine ◽

10.3858/emm.2009.41.6.046 ◽

2009 ◽

Vol 41 (6) ◽

pp. 406 ◽

Cited By ~ 10

Author(s):

Jae Hoon Jeong ◽

Sehyung Cho ◽

Youngmi Kim Pak

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Very low density lipoprotein receptor promotes adipocyte differentiation and mediates the proadipogenic effect of peroxisome proliferator-activated receptor gamma agonists

Biochemical Pharmacology ◽

10.1016/j.bcp.2011.09.003 ◽

2011 ◽

Vol 82 (12) ◽

pp. 1950-1962 ◽

Cited By ~ 8

Author(s):

Huan Tao ◽

Tahar Hajri

Keyword(s):

Adipocyte Differentiation ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Very Low Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Peroxisome proliferator-activated receptor α ligands activate transcription of lectin-like oxidized low density lipoprotein receptor-1 gene through GC box motif

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2004.08.193 ◽

2004 ◽

Vol 323 (3) ◽

pp. 1116-1123 ◽

Cited By ~ 5

Author(s):

Kazutaka Hayashida ◽

Noriaki Kume ◽

Manabu Minami ◽

Atsuko Inui-Hayashida ◽

Eri Mukai ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Oxidized Low Density Lipoprotein ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor ◽

Gc Box

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Activation of peroxisome proliferator-activated receptor-α in mice induces expression of the hepatic low-density lipoprotein receptor

British Journal of Pharmacology ◽

10.1038/bjp.2008.331 ◽

2008 ◽

Vol 155 (4) ◽

pp. 596-605 ◽

Cited By ~ 34

Author(s):

Z Huang ◽

X Zhou ◽

A C Nicholson ◽

A M Gotto ◽

D P Hajjar ◽

...

Keyword(s):

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Peroxisome Proliferator ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Peroxisome Proliferator Activated Receptor ◽

Density Lipoprotein Receptor

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Low-density lipoprotein receptor-knockout mice display impaired spatial memory associated with a decreased synaptic density in the hippocampus

Neurobiology of Disease ◽

10.1016/j.nbd.2004.01.015 ◽

2004 ◽

Vol 16 (1) ◽

pp. 212-219 ◽

Cited By ~ 65

Author(s):

Monique Mulder ◽

Paula J Jansen ◽

Ben J.A Janssen ◽

Wilma D.J van de Berg ◽

Hans van der Boom ◽

...

Keyword(s):

Spatial Memory ◽

Knockout Mice ◽

Low Density Lipoprotein ◽

Density Lipoprotein ◽

Low Density ◽

Lipoprotein Receptor ◽

Low Density Lipoprotein Receptor ◽

Synaptic Density ◽

Density Lipoprotein Receptor

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