scholarly journals Bone Mineral Density in Acute Stroke Patients

Stroke ◽  
2001 ◽  
Vol 32 (1) ◽  
pp. 47-51 ◽  
Author(s):  
Lone Jørgensen ◽  
Torgeir Engstad ◽  
Bjarne K. Jacobsen
Keyword(s):  
Bone Mineral Density ◽  
Acute Stroke ◽  
Bone Mineral ◽  
Mineral Density ◽  
Stroke Patients

scholarly journals Low Bone Mineral Density Could Predict Cognitive Impairment during the Acute and Recovery Phases of Ischemic Stroke

2019 ◽  
Author(s):  
Sang-Hwa Lee ◽  
Min Uk Jang ◽  
Yerim Kim ◽  
So Young Park ◽  
Chulho Kim ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Lumbar Spine ◽  
Cognitive Function ◽  
Femoral Neck ◽  
Acute Stroke ◽  
Bone Mineral ◽  
Recovery Phase ◽  
Mineral Density

Abstract Background: Little is known about the effect of osteoporosis at the acute and recovery phase of stroke on cognitive function. We evaluated the effect of osteoporosis on cognitive function in patients with ischemic stroke aged >50 years.Methods: We retrospectively examined consecutive patients with acute stroke hospitalized between 2016 and 2018. Osteoporosis was defined as a T score of <-2.5 for the femoral neck or lumbar spine bone mineral density. The primary outcome was cognitive impairment measured by the Korean Mini-Mental State Examination in the acute phase and recovery phase of ischemic stroke. The association between osteoporosis and the severity of cognitive impairment was investigated using a multivariate analysis.Results: Of the 260 included subjects (107 men and 153 women), 70 (26.9%) had osteoporosis. Cognitive impairment was more severe in the osteoporosis group than in the non-osteoporosis group (30.5% versus 47.1%, p=0.001). After recovery phase of stroke, the proportion of patients with cognitive impairment remained higher in the osteoporosis group. The multivariate analysis revealed a correlation between a low femoral neck bone mineral density and severe cognitive impairment in the acute and recovery phases of stroke (adjusted odds ratio [OR] 3.66, 95% confidence interval [CI] 1.05-12.79 in the acute phase and adjusted OR 11.17, 95% CI 1.12-110.98 in the recovery phase), whereas lumbar spine osteoporosis was not associated with cognitive impairment.Conclusions: Low bone mineral density is associated with poor cognitive function in patients with acute stroke. Early bone mineral density assessments during acute stroke, particularly at the femoral neck, may be a useful marker of cognitive function.

scholarly journals The associations between bone mineral density and cerebral white matter hyperintensity in elderly stroke patients

2018 ◽  
Vol 2 (3) ◽  
pp. 117-123
Author(s):  
Ji-Sun Kim ◽  
Minjik Kim ◽  
Sung Hoon Kang ◽  
Kyungmi Oh ◽  
Sangil Suh ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
White Matter ◽  
Bone Mineral ◽  
White Matter Hyperintensity ◽  
Cerebral White Matter ◽  
Mineral Density ◽  
Stroke Patients

Prevalence of pre-stroke low bone mineral density and vertebral fracture in first stroke patients

Bone ◽  
2008 ◽  
Vol 43 (1) ◽  
pp. 183-186 ◽  
Author(s):  
Hye Won Kim ◽  
Eugene Kang ◽  
Sun Im ◽  
Young Jin Ko ◽  
Soo Ah Im ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vertebral Fracture ◽  
Bone Mineral ◽  
Mineral Density ◽  
Stroke Patients ◽  
Low Bone Mineral Density

scholarly journals Low Bone Mineral Density Could Predict Cognitive Impairment during the Acute and Recovery Phases of Ischemic Stroke

2020 ◽  
Author(s):  
Sang-Hwa Lee ◽  
Min Uk Jang ◽  
Yerim Kim ◽  
So Young Park ◽  
Chulho Kim ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Multivariate Analysis ◽  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Femoral Neck ◽  
Acute Stroke ◽  
Bone Mineral ◽  
Recovery Phase ◽  
Mineral Density

Abstract Background Little is known about the effect of osteoporosis at the acute and recovery phase of stroke on cognitive function. We evaluated the effect of osteoporosis on cognitive function in patients with ischemic stroke aged >50 years. Methods We retrospectively examined consecutive patients with acute stroke hospitalized between 2016 and 2018. Osteoporosis was defined as a T score of <-2.5 for the femoral neck or lumbar spine bone mineral density. The primary outcome was cognitive impairment measured by the Korean Mini-Mental State Examination in the acute phase and recovery phase of ischemic stroke. The association between osteoporosis and the severity of cognitive impairment was investigated using a multivariate analysis. Results Of the 260 included subjects (107 men and 153 women), 70 (26.9%) had osteoporosis. Cognitive impairment was more severe in the osteoporosis group than in the non-osteoporosis group (30.5% versus 47.1%, p=0.001). After recovery phase of stroke, the proportion of patients with cognitive impairment remained higher in the osteoporosis group. The multivariate analysis revealed a correlation between a low femoral neck bone mineral density and severe cognitive impairment in the acute and recovery phases of stroke (adjusted odds ratio [OR] 3.66, 95% confidence interval [CI] 1.05-12.79 in the acute phase and adjusted OR 11.17, 95% CI 1.12-110.98 in the recovery phase), whereas lumbar spine osteoporosis was not associated with cognitive impairment. Conclusions Low bone mineral density is associated with poor cognitive function in patients with acute stroke. Early bone mineral density assessments during acute stroke, particularly at the femoral neck, may be a useful marker of cognitive function.

scholarly journals Bone mineral density and fragility fractures in stroke patients

2019 ◽  
Vol 0 (6) ◽  
Author(s):  
V. V. Povorozniuk ◽  
M. A. Bystrytska ◽  
N. V Hryhorieva
Keyword(s):  
Bone Mineral Density ◽  
Bone Mineral ◽  
Fragility Fractures ◽  
Mineral Density ◽  
Stroke Patients

scholarly journals Low Bone Mineral Density Could Predict Cognitive Impairment during the Acute and Recovery Phases of Ischemic Stroke

2019 ◽  
Author(s):  
Sang-Hwa Lee ◽  
Min Uk Jang ◽  
Yerim Kim ◽  
So Young Park ◽  
Chulho Kim ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Multivariate Analysis ◽  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Femoral Neck ◽  
Acute Stroke ◽  
Bone Mineral ◽  
Recovery Phase ◽  
Mineral Density

Abstract Background Little is known about the effect of osteoporosis at the acute and recovery phase of stroke on cognitive function. We evaluated the effect of osteoporosis on cognitive function in patients with ischemic stroke aged >50 years. Methods We retrospectively examined consecutive patients with acute stroke hospitalized between 2016 and 2018. Osteoporosis was defined as a T score of <-2.5 for the femoral neck or lumbar spine bone mineral density. The primary outcome was cognitive impairment measured by the Korean Mini-Mental State Examination in the acute phase and recovery phase of ischemic stroke. The association between osteoporosis and the severity of cognitive impairment was investigated using a multivariate analysis. Results Of the 260 included subjects (107 men and 153 women), 70 (26.9%) had osteoporosis. Cognitive impairment was more severe in the osteoporosis group than in the non-osteoporosis group (30.5% versus 47.1%, p=0.001). After recovery phase of stroke, the proportion of patients with cognitive impairment remained higher in the osteoporosis group. The multivariate analysis revealed a correlation between a low femoral neck bone mineral density and severe cognitive impairment in the acute and recovery phases of stroke (adjusted odds ratio [OR] 3.66, 95% confidence interval [CI] 1.05-12.79 in the acute phase and adjusted OR 11.17, 95% CI 1.12-110.98 in the recovery phase), whereas lumbar spine osteoporosis was not associated with cognitive impairment. Conclusions Low bone mineral density is associated with poor cognitive function in patients with acute stroke. Early bone mineral density assessments during acute stroke, particularly at the femoral neck, may be a useful marker of cognitive function.

Abstract TP190: Bone Mineral Density is Inversely Related to Cerebral Pulsatility Index in Patients With Acute Ischemic Stroke

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Sang Won Han ◽  
Joong Hyun Park ◽  
Jong Yun Lee ◽  
Seong Hwan Ahn ◽  
Kyung-Yul Lee
Keyword(s):  
Bone Mineral Density ◽  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Bone Mineral ◽  
Pulsatility Index ◽  
Vascular System ◽  
Linear Regression Analysis ◽  
Mineral Density ◽  
Stroke Patients ◽  
T Score

Introduction: Atherosclerosis and osteoporosis are two major public health problems. These are both multifactorial and degenerative diseases that accompany aging. Co-morbidities are common, with a high prevalence of cardiovascular risk factors including hypertension, smoking, and sedentary lifestyle. Several studies have suggested a relationship between atherosclerosis and osteoporosis, with a significant correlation between coronary artery calcium and bone mineral density (BMD). The pulsatility index (PI) is designed to measure vascular resistance and characterizes the shape of the spectral waveform. The PI was increasing with age but alterations in PI are the reflection of multifactorial, pleiotropic events occurring in the cardio and cerebral vascular system. Atherosclerosis of the large proximal arteries and the intracranial vessels are important factors for increased PI. Hypothesis: We hypothesized that the transcranial Doppler (TCD) PI would reflect the atherosclerotic component of intracranial vessels which in turn is related to systemic atherosclerosis. In this context, we investigated the relationship between TCD PI and BMD in acute ischemic stroke patients. Methods: Patients having their first ischemic stroke within 7 days were screened for the study. Doppler signals from the main stem of the middle cerebral artery (MCA) were obtained transtemporally with a traditional 2-MHz transducer at depths of 56, 58, and 60 mm. BMD was measured at total hip and lumbar spine in the anterior-posterior projection, using dual-energy x-ray absorptiometry. Results: A total of 146 patients were enrolled in the study and the mean age was 68.3±10.34 years. Multiple linear regression analysis reveals that age (p<0.001) and BMD T-score (p=0.028) were significantly associated with increased TCD PI. Old age and decreased T-score were significantly related to increased TCD PI. Age adjusted scatterplots showed that BMD T-score was inversely related to TCD PI in acute ischemic stroke patients (r=-0.202, p=0.028). Conclusions: Our findings indicate that decreased BMD may be associated with atherosclerosis in the cerebral circulation.

scholarly journals Association between Osteoporosis and Cognitive Impairment during the Acute and Recovery Phases of Ischemic Stroke

Medicina ◽  
2020 ◽  
Vol 56 (6) ◽  
pp. 307
Author(s):  
Sang-Hwa Lee ◽  
So Young Park ◽  
Min Uk Jang ◽  
Yerim Kim ◽  
Jungyoup Lee ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Ischemic Stroke ◽  
Cognitive Impairment ◽  
Cognitive Function ◽  
Femoral Neck ◽  
Acute Stroke ◽  
Bone Mineral ◽  
Acute Phase ◽  
Recovery Phase ◽  
Mineral Density

Background and objectives: Little is known about the effect of osteoporosis on cognitive function in the acute and recovery phases of stroke. Early bone mineral density assessments during acute stroke may be a useful marker of cognitive function. We evaluated the effect of osteoporosis on cognitive function at the early and recovery phase of ischemic stroke in patients aged >50 years. Materials and Methods: We retrospectively examined consecutive patients with acute stroke hospitalized between 2016 and 2018. Osteoporosis was defined as a T-score <–2.5 for the femoral neck or lumbar spine bone mineral density. The primary outcome was cognitive impairment measured by the Korean Mini-Mental State Examination in the acute phase and recovery phase of ischemic stroke. Results: Of the 260 included subjects (107 men and 153 women), 70 (26.9%) had osteoporosis. Cognitive impairment was more severe in the osteoporosis group than in the non-osteoporosis group (30.5% versus 47.1%, p = 0.001). After the recovery phase of stroke, the proportion of patients with cognitive impairment remained higher in the osteoporosis group. The multivariate analysis revealed a correlation between a low femoral neck bone mineral density and severe cognitive impairment in the acute and recovery phases of stroke (adjusted odds ratio (OR) 4.09, 95% confidence interval (CI) 1.11–15.14 in the acute phase, and adjusted OR 11.17, 95% CI 1.12–110.98 in the recovery phase). Conclusions: Low bone mineral density is associated with poor cognitive function in the acute and recovery phases of stroke.

Sign in / Sign up

Export Citation Format

Share Document