scholarly journals Decreased Perihematomal Edema in Thrombolysis-Related Intracerebral Hemorrhage Compared With Spontaneous Intracerebral Hemorrhage

Stroke ◽  
2000 ◽  
Vol 31 (3) ◽  
pp. 596-600 ◽  
Author(s):  
James M. Gebel ◽  
Thomas G. Brott ◽  
Cathy A. Sila ◽  
Thomas A. Tomsick ◽  
Edward Jauch ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

scholarly journals Fully Automated Segmentation Algorithm for Perihematomal Edema Volumetry After Spontaneous Intracerebral Hemorrhage

Stroke ◽  
2020 ◽  
Vol 51 (3) ◽  
pp. 815-823 ◽  
Author(s):  
Natasha Ironside ◽  
Ching-Jen Chen ◽  
Simukayi Mutasa ◽  
Justin L. Sim ◽  
Dale Ding ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Segmentation Algorithm ◽  
Automated Segmentation ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

scholarly journals Spreading depolarizations in patients with spontaneous intracerebral hemorrhage: Association with perihematomal edema progression

2016 ◽  
Vol 37 (5) ◽  
pp. 1871-1882 ◽  
Author(s):  
Raimund Helbok ◽  
Alois Josef Schiefecker ◽  
Christian Friberg ◽  
Ronny Beer ◽  
Mario Kofler ◽  
...  
Keyword(s):  
Brain Injury ◽  
Intracerebral Hemorrhage ◽  
Electrode Placement ◽  
Secondary Brain Injury ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Strip Electrode ◽  
Hematoma Evacuation ◽  
Perihematomal Edema ◽  
Pathophysiologic Mechanisms

Pathophysiologic mechanisms of secondary brain injury after intracerebral hemorrhage and in particular mechanisms of perihematomal-edema progression remain incompletely understood. Recently, the role of spreading depolarizations in secondary brain injury was established in ischemic stroke, subarachnoid hemorrhage and traumatic brain injury patients. Its role in intracerebral hemorrhage patients and in particular the association with perihematomal-edema is not known. A total of 27 comatose intracerebral hemorrhage patients in whom hematoma evacuation and subdural electrocorticography was performed were studied prospectively. Hematoma evacuation and subdural strip electrode placement was performed within the first 24 h in 18 patients (67%). Electrocorticography recordings started 3 h after surgery (IQR, 3–5 h) and lasted 157 h (median) per patient and 4876 h in all 27 patients. In 18 patients (67%), a total of 650 spreading depolarizations were observed. Spreading depolarizations were more common in the initial days with a peak incidence on day 2. Median electrocorticography depression time was longer than previously reported (14.7 min, IQR, 9–22 min). Postoperative perihematomal-edema progression (85% of patients) was significantly associated with occurrence of isolated and clustered spreading depolarizations. Monitoring of spreading depolarizations may help to better understand pathophysiologic mechanisms of secondary insults after intracerebral hemorrhage. Whether they may serve as target in the treatment of intracerebral hemorrhage deserves further research.

scholarly journals Natural History of Perihematomal Edema in Patients With Hyperacute Spontaneous Intracerebral Hemorrhage

Stroke ◽  
2002 ◽  
Vol 33 (11) ◽  
pp. 2631-2635 ◽  
Author(s):  
James M. Gebel ◽  
Edward C. Jauch ◽  
Thomas G. Brott ◽  
Jane Khoury ◽  
Laura Sauerbeck ◽  
...  
Keyword(s):  
Natural History ◽  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
History Of ◽  
Perihematomal Edema

scholarly journals The risk factors and prognosis of delayed perihematomal edema in patients with spontaneous intracerebral hemorrhage

2019 ◽  
Vol 25 (10) ◽  
pp. 1189-1194 ◽  
Author(s):  
Wen‐jie Peng ◽  
Qian Li ◽  
Jin‐hua Tang ◽  
Cesar Reis ◽  
Camila Araujo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

scholarly journals Perihematomal edema surrounding spontaneous intracerebral hemorrhage by CT

Medicine ◽  
2020 ◽  
Vol 99 (28) ◽  
pp. e20951
Author(s):  
Julie G. Shulman ◽  
Hernan Jara ◽  
Muhammad M. Qureshi ◽  
Helena Lau ◽  
Brandon Finn ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

scholarly journals Perihematomal Edema After Spontaneous Intracerebral Hemorrhage

Stroke ◽  
2019 ◽  
Vol 50 (6) ◽  
pp. 1626-1633 ◽  
Author(s):  
Natasha Ironside ◽  
Ching-Jen Chen ◽  
Dale Ding ◽  
Stephan A. Mayer ◽  
Edward Sander Connolly
Keyword(s):  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

Impact of Perihematomal Edema on Infectious Complications after Spontaneous Intracerebral Hemorrhage

2021 ◽  
Vol 30 (7) ◽  
pp. 105827
Author(s):  
Daina Kashiwazaki ◽  
Takahiro Tomita ◽  
Takashi Shibata ◽  
Shusuke Yamamoto ◽  
Emiko Hori ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Infectious Complications ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema

Abstract W P326: Comparison of Spontaneous Intracerebral Hemorrhage Outcomes in Patients with Warfarin and Antiplatelet Medication Use

Stroke ◽  
2015 ◽  
Vol 46 (suppl_1) ◽  
Author(s):  
Santosh Murthy ◽  
Yogesh Moradiya ◽  
Jesse Dawson ◽  
Kennedy Lees ◽  
Daniel F Hanley ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Functional Outcomes ◽  
Intraventricular Hemorrhage ◽  
Hematoma Expansion ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Hematoma Volume ◽  
Computed Tomographic ◽  
Warfarin Group ◽  
Antiplatelet Medication ◽  
Perihematomal Edema

Background: Use of antiplatelet medications and warfarin has been associated with poor clinical outcomes in spontaneous intracerebral hemorrhage (ICH). However, a head to head comparison between these groups has not been performed. We compared ICH outcomes among patients on these medications. Methods: In this cohort study, we analyzed 987 patients with ICH from the Virtual International Stroke Trials Archive. Patients with ICH presented within six-hours of symptom onset had baseline clinical, radiological data, and computed tomographic scan at 72 hours. Hematoma expansion was defined as interval increase in size by >33%. Main outcome variables were 90-day mortality, and modified Rankin Score (mRS) at 90 days dichotomized into 0-3 vs 4-6. Results: Of 987 ICH patients 154 had prior antiplatelet use, 30 had warfarin, and 803 had neither of the two medications. The warfarin group had significantly higher age (p<0.001) and higher prevalence of atrial fibrillation (p<0.001). Of the ICH characteristics, comparing warfarin, antiplatelet and no warfarin/antiplatelet cohorts, the warfarin group had lower Glasgow coma scale (GCS) scores (p=0.049), higher intraventricular hemorrhage (IVH) rate (p=0.010), and more hydrocephalus (p<0.001). Hematoma expansion at 72 hours was significantly higher with warfarin use (p=0.003), while the ratio of perihematomal edema volume to hematoma volume at 72 hours was lowest with warfarin use (p<0.001). In the logistic regression model adjusted for age, sex, race, hematoma volume, perihematomal edema, GCS, IVH and hydrocephalus; warfarin patients had significantly lower odds of achieving mRS 0-3 (OR: 0.23, 95% CI: 0.06-0.83, p=0.025), while the antiplatelet group had similar functional outcomes compared to no warfarin/antiplatelet use (OR: 0.75, 95% CI: 0.46-1.23, p=0.260). The 90-day mortality outcomes were not significantly different across the three groups (18.7% to 40.3%, p=0.520). Conclusion: Warfarin use is associated with a higher incidence of hydrocephalus, intraventricular hemorrhage and hematoma expansion, but lesser perihematomal edema relative to the hematoma volume. Warfarin associated ICH appears to be independently associated with worse functional outcomes but not with 90-day mortality in ICH.

No exacerbation of perihematomal edema with intraclot urokinase in patients with spontaneous intracerebral hemorrhage

2014 ◽  
Vol 156 (9) ◽  
pp. 1735-1744 ◽  
Author(s):  
Lifei Lian ◽  
Feng Xu ◽  
Qi Hu ◽  
Qiming Liang ◽  
Wenhao Zhu ◽  
...  
Keyword(s):  
Intracerebral Hemorrhage ◽  
Spontaneous Intracerebral Hemorrhage ◽  
Perihematomal Edema
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