Detection of Cerebral Microemboli by Means of Transcranial Doppler Monitoring Before and After Carotid Endarterectomy

Stroke ◽  
1995 ◽  
Vol 26 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Erik V. van Zuilen ◽  
Frans L. Moll ◽  
Freddie E.E. Vermeulen ◽  
Henk W. Mauser ◽  
Jan van Gijn ◽  
...  
Keyword(s):  
Carotid Endarterectomy ◽  
Transcranial Doppler ◽  
Before And After

scholarly journals Evaluation of cerebrovascular hemodynamics in patients with idiopathic intracranial hypertension using transcranial Doppler

2020 ◽  
Vol 56 (1) ◽  
Author(s):  
Mahmoud M. Allam ◽  
Hatem A. Almasry ◽  
Sandra M. Ahmed ◽  
Youssuf G. Taha ◽  
Mohammed I. Oraby
Keyword(s):  
Intracranial Pressure ◽  
Intracranial Hypertension ◽  
Lumbar Puncture ◽  
Transcranial Doppler ◽  
Idiopathic Intracranial Hypertension ◽  
Pulsatility Index ◽  
Research Work ◽  
Increased Intracranial Pressure ◽  
Significant Relation ◽  
Before And After

Abstract Background Idiopathic intracranial hypertension (IIH) is a disorder of increased intracranial pressure without a clear cause and can have serious visual effects. Previous research work suggests that transcranial Doppler measurements of pulsatility index correlate accurately with elevated intracranial pressure. Objective To assess the cerebrovascular hemodynamic changes in patients with IIH using transcranial Doppler before and after lumbar puncture and CSF withdrawal. Methods An interventional study conducted on 40 patients (31 females and 9 males) fulfilling the modified Dandy criteria for diagnosis of idiopathic intracranial hypertension, MRI brain, and MRV was done to the patients. Lumbar puncture was done for all included patients to measure intracranial pressure and CSF withdrawal. Transcranial Doppler was performed for all included before and after lumbar puncture and CSF withdrawal and the following parameters were measured: peak systolic velocity (PSV), end diastolic velocity (EDV), resistivity index (RI), and pulsatility index (PI). Results Significant relation was found between grades of papilledema and PSV, RI, and PI (p value 0.012, 0.025, 0.016) but no significant relation was found between grades of papilledema and EDV (0.102). Significant changes occurred in parameters of TCD pre- and post-CSF withdrawal including PSV, EDV, and PI (p value 0.001, 0.015, 0.019) denoting a significant change in cerebral hemodynamics after CSF withdrawal which denotes a decrease in intracranial pressure. Conclusion Increased intracranial pressure significantly affects cerebral blood flow. A normalization of transcranial Doppler parameters occurs following lowering of intracranial pressure through lumbar puncture and CSF withdrawal.

Cerebral Blood Flow before and After Carotid Endarterectomy

1972 ◽  
Vol 6 (1) ◽  
pp. 14-19 ◽  
Author(s):  
H.C. Engell ◽  
Gudrun Boysen ◽  
H.J. Ladegaard-Pedersen ◽  
H. Henriksen
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Carotid Endarterectomy ◽  
Before And After

scholarly journals Prediction of Cerebral Hyperperfusion after Carotid Endarterectomy with Transcranial Doppler

2012 ◽  
Vol 55 (4) ◽  
pp. 1222 ◽  
Author(s):  
C.W.A. Pennekamp ◽  
S.C. Tromp ◽  
R.G.A. Ackerstaff ◽  
M.L. Bots ◽  
R.V. Immink ◽  
...  
Keyword(s):  
Carotid Endarterectomy ◽  
Transcranial Doppler ◽  
Cerebral Hyperperfusion

Abstract TP401: Chemotherapy-associated Cerebral Vasospasm in Children With Leukemia: A Prospective Study Using Transcranial Doppler Ultrasound

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Lisa R Sun ◽  
Wendy C Ziai ◽  
Ryan J Felling
Keyword(s):  
Cerebral Vasospasm ◽  
Induction Chemotherapy ◽  
Transcranial Doppler ◽  
Clinical Pathways ◽  
Case Reports ◽  
Antineoplastic Agent ◽  
Medication Administration ◽  
Pediatric Leukemia ◽  
Before And After ◽  
Neurologic Sequelae

Introduction: Intrathecal (IT) cytarabine, an antineoplastic agent with poorly understood neurotoxicity, is commonly administered to children with newly diagnosed leukemia on the first day of induction chemotherapy for central nervous system prophylaxis. Five recent case reports demonstrated severe diffuse cerebral vasospasm leading to neurologic sequelae 4-11 days after administration of IT cytarabine. While these patients developed overt consequences, subclinical vasospasm may lead to more subtle forms of neurotoxicity in a larger group of patients. Recognition of subclinical vasospasm could prevent both overt and subtle consequences. Objective and Hypothesis: We evaluated cerebral blood flow velocities (CBFVs), a marker of vasospasm, as measured by transcranial Doppler (TCD) ultrasound, before and after the administration of IT cytarabine. We hypothesized that IT cytarabine increases CBFVs in pediatric leukemia patients in the first two weeks after treatment. Methods: In this prospective before and after study, TCDs were performed on each subject prior to induction chemotherapy and subsequently around days +1, +4, and +8 of induction, before other IT medication administration and within the window of expected vasospasm based on prior cases. Results: In this interim analysis, we found elevated CBFVs compared to age-matched normal values in all arterial distributions measured (though more prominently in anterior circulation), even prior to the administration of IT chemotherapy. Substantial increases in CBFVs were observed after the administration of IT cytarabine in some subjects, though this trend was not observed in all cases. Conclusions: The observed elevations in CBFVs are likely in part due to decreased blood viscosities that resulted from hematologic changes secondary to leukemia. The observed changes in CBFVs after IT cytarabine administration are probably partially due to treatment effects, but the variability between patients suggests that patient and/or disease-specific characteristics may predispose certain children to cerebral vasospasm and its neurologic sequelae. This ongoing study aims to identify clinical features that allow risk stratification in order to develop clinical pathways for preventing neurotoxicity.

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