Blood Pressure Level and Variability in the Prediction of Blood Pressure After 5-Year Follow-up

Hypertension ◽  
1996 ◽  
Vol 28 (5) ◽  
pp. 725-731 ◽  
Author(s):  
Silja Majahalme ◽  
Väinö Turjanmaa ◽  
Alan B. Weder ◽  
Hong Lu ◽  
Martti T. Tuomisto ◽  
...  
2019 ◽  
Vol 47 (4) ◽  
pp. 299-309
Author(s):  
V. E. Uspenskiy ◽  
E. G. Malev ◽  
N. D. Gavriliuk ◽  
B. K. Salavatov ◽  
S. A. Ermolov ◽  
...  

Background: Ascending aortic (AA) dilatation is common in patients with bicuspid aortic valve (BAV). In BAV replacement, surgery of the AA is indicated in the case if AA diameter exceeds 45 mm. Aortic valve replacement combined with an AA intervention is associated with increased risk of complications. The feasibility of the reduction ascending aortoplasty for correction of the dilated AA remains disputable.Aim: To analyze the results of BAV surgical replacement with simultaneous surgical correction of the borderline AA dilatation (45-50 mm) by the reduction aortoplasty (RAP) or supracoronary AA replacement (SPR).Materials and methods: This single center prospective non-randomized study included 53 patients with significant BAV stenosis and AA dilatation (45-50 mm), divided into 2 groups: BAV surgical replacement combined with RAP AA replacement (group 1, 36 patients) and BAV replacement with SPR (group 2, 17 patients). There were no significant differences between the patients of the two groups in their characteristics of the underlying disease, complications and comorbidities.Results: Hospital mortality was 0%. No between-group differences in the early postoperative course were found. At later term, 44 (81.5%) patients were assessed; median (dispersion) of the follow-up was 36 (25; 50) months. Two patients from the group 2 died during the follow-up. The long-term survival was better in the group 1 (p = 0.028). No differences in the combined adverse event rate were observed between the groups (p = 0.633). The median (dispersion) of the AA absolute increment and the rate of dilatation after RAP were 1.0 (0.0; 3.0) mm and 0.24 (0.00; 0.95) mm/year, respectively. The predictor of AA increment rate ≥ 2 mm/year was the baseline blood pressure level (odds ratio 1.321, 95% confidence interval 1.050-1.662; p=0.017). The threshold preoperative blood pressure value for the increased risk of the long-term AA expansion rate was 138 mmHg.Conclusion: The efficacy and safety of RAP and SRP combined with BAV replacement in AA borderline dilatation are similar. Combined BAV surgery and RAP is effective and safe in patients with systolic blood pressure level ≤ 135 mmHg. Combined BAV replacement with SRP seems reasonable in patients with arterial hypertension.


2001 ◽  
Vol 19 (7) ◽  
pp. 1193-1201 ◽  
Author(s):  
Jaana M. Jokiniitty ◽  
Silja K. Majahalme ◽  
Mika A. P. Kähönen ◽  
Martti T. Tuomisto ◽  
Väinö M. H. Turjanmaa

1995 ◽  
Vol 13 (8) ◽  
pp. 909-913 ◽  
Author(s):  
Lise Lund H??heim ◽  
Ingar Holme ◽  
Ingvar Hjermann ◽  
Paul Leren

2005 ◽  
Vol 24 (1) ◽  
pp. 77-87 ◽  
Author(s):  
Martti T. Tuomisto ◽  
Silja Majahalme ◽  
Mika Kähönen ◽  
Mats Fredrikson ◽  
Väinö Turjanmaa

2020 ◽  
Vol 30 (6) ◽  
Author(s):  
Samuel Dessu Sifer ◽  
Fikre Bojola ◽  
Zinabu Dawit ◽  
Habtamu Samuel ◽  
Mulugeta Dalbo

BACKGROUND፡ Pregnancy induced hypertension represents a significant public health problem throughout the world, which may complicate 0.5%–10% of all pregnancies. It is the leading cause of maternal as well perinatal mortality and morbidity worldwide. Pregnancy induced hypertension is a multisystem disorder unique to pregnancy and results in high perinatal mortality. The objective of this study was to determine the survival status, incidence and predictors of perinatal mortality among mothers with pregnancy induced hypertension at antenatal clinics of Gamo Zone public hospitals.METHODS: Facility-based retrospective cohort study was conducted among selected 576(192 exposed and 384 unexposed) antenatal care attendants' record at Gamo Zone public hospitals from 1st January 2018 to 31st December 2018. Data were entered into Epi data version 3.02 and exported to SPSS V 25 for analysis. Kaplan Meier survival curve together with log rank test was fitted to test the survival time. Statistical significance was declared at Pvalue <0.05 using cox proportional hazard model.RESULT: The incidence of perinatal mortality was 124/1000 births. The cumulative proportion of surviving at the end of 4th , 8th, 12th and 16th weeks of follow-up among the exposed groups was 96.9%, 93.5%, 82.1% and 61.6% respectively whereas it was 99.5%, 98.9% and 98.5% at the end of 4th, 8th and 12th weeks of follow-up for the non-exposed groups respectively. Parity of >5(AHR: 6.3; 95%CI: 1.36,10.55), mothers who delivered at<34 weeks of gestation(AHR:7.8; 95%CI: 2.6,23.1), being preterm(AHR:6; 95%CI: 5.3,19.2), perinatal birth weight<2500gm(AHR:6.1; 95&CI: 1.01,37.9), vaginal deliveryn(AHR:2.7; 95%CI:1.13,6.84), maternal highest systolic blood pressure level >160mmHg (AHR: 2.3; 95%CI: 1.02,5.55) and prepartum onset of pregnancy induced hypertension (AHR:6; 95%CI: 5.3,19.2) were statistically significant in multivariable analysis.CONCLUSION: The risk of perinatal mortality was high among the mothers with pregnancy induced hypertension compared to those of pregnancy induced hypertension free mother,s and the perinatal mortality rate was high. High parity, low gestational age, low number of antenatal care visits, low birth weight, vaginal delivery, antepartum onset of pregnancy induced hypertension and highest maternal systolic blood pressure level were the independent predictors of perinatal mortality.


Circulation ◽  
2012 ◽  
Vol 125 (suppl_10) ◽  
Author(s):  
Christina Stahl-Heden@ ◽  
Lena M Bjorck ◽  
Masuma Novak ◽  
Wai Giang Kok ◽  
Per-Olof Hansson ◽  
...  

Introduction and Aim: The link between diabetes type 2 and hypertension is a well established with both factors parts of the metabolic syndrome. Whether hypertension is an independent predictor for diabetes type 2 development has been examined in previous studies, however with divergent findings. The aim of this study was to investigate whether hypertension, including mildly elevated blood pressure within the normal range predicted subsequent development of diabetes type 2 over an extended follow-up. Methods and Results: Data were derived from participants of the intervention group of the Gothenburg primary prevention study where a random sample of 7333 men aged 47-55 years and free of diagnosed diabetes underwent a screening investigation in 1970 to 1973. During a 32-year follow-up, 956 men (13%) were diagnosed with diabetes according to the Swedish hospital discharge register. Development of diabetes type 2 was positively correlated to age, BMI, systolic blood pressure (SBP) and diastolic blood pressure (DBP), serum cholesterol, hypertension treatment, non-manual occupation, high tobacco use, sedentary lifestyle at the midlife screening. In a Cox regression model which adjusted for BMI and other risk factors we calculated the multiple adjusted hazard ratio for developing diabetes type 2 according to blood pressure level. Compared to a reference level of systolic blood pressure (SBP) below 130 mm Hg, men with SBP of 130-139 mmHg, 140-149 mmHg and > 150 mmHg had a multiple adjusted hazard ratios (HRs) of 1.41 (95% confidence interval) 1.11–1.80), 1.38 (1.08–1.75) and 1.67 (1.35–2.07), respectively. Mid-life diastolic blood pressure over 90 mmHg was associated to an increased risk of developing diabetes type 2 (multiple adjust HRs of 1,60 1,21–2,11) Conclusion: In this population, at mid-life, hypertension as well as moderately elevated systolic blood pressure levels within the normal range was shown to be independent predictors of diabetes type 2.


1980 ◽  
Vol 8 (1) ◽  
pp. 17-23 ◽  
Author(s):  
Aulikki Nissinen ◽  
Jaakko Tuomilehto ◽  
Pekka Puska

A major subprogramme of the North Karelia Project has been the hypertension programme which aimed at lowering the high blood pressure levels prevalent among the whole population of the province of North Karelia, and especially among middle-aged men. A community-based hypertension register, which served as the major tool of the programme, was established to keep patients under treatment and to gather information about the progress of the programme. The registration of the hypertensive subjects was continued from 1972 to 1977; the registered patients had annual follow-up examinations. After 5 years of the programme, there were approximately 17000 registered patients, which was 9.7% of the total population. The proportion of drop-outs at the annual follow-up examinations was 10–20%. 83% of the registered hypertensive subjects were undergoing drug treatment after 3 years' intervention. The percentage of normotensive subjects increased significantly year by year.


2019 ◽  
Vol 24 (6) ◽  
pp. 693-703
Author(s):  
E. A. Lopina ◽  
R. A. Libis

Objective. To assess the impact of the achieved blood pressure level on the structure and function of kidneys, carotid arteries and depression level in hypertensive post-stroke survivors.Design and methods.Carotid arteries and kidneys were assessed by ultrasound study. All parameters including depression level (Hamilton scale) were evaluated depending on the achieved systolic blood pressure level (SBP) in 88 hypertensive patients in acute post-stroke period and at follow-up (8–12 months after stroke). Multiple regression analysis was applied to assess the associations between the factors.Results.Office SBP directly correlates with the creatinine level (r = 0,5; р = 0,01). Moderate direct correlation was found between mean office SBP at the follow-up visit and intima-media thickness (IMT) (r = 0,47; р = 0,004), resistance index of the right common carotid artery (CCA) (r = 0,47; р = 0,006), resistance index of the left CCA (r = 0,5; р = 0,002), and resistance index of the left internal carotid artery (ICA) (r = 0,4; р = 0,02). Regression analysis demonstrated that mean office SBP has an impact on the following parameters: plasma creatinine level (β = 0,43; р = 0,04) and CCA IMT (β = 0,36; р = 0,03). The depression decreased in subjects with SBP 125–134 mmHg.Conclusion. SBP stabilization at the level 125–134 mmHg leads to the decrease in the resistance index of the carotid arteries, improves renal function and reduces depression level in post-stroke survivors.


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