Poor Glycemic Control Induces Hypertension in Diabetes Mellitus

Hypertension ◽  
1996 ◽  
Vol 27 (3) ◽  
pp. 735-739 ◽  
Author(s):  
Michael W. Brands ◽  
Timothy E. Hopkins
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Poor Glycemic Control

scholarly journals Laboratory Parameters of Hemostasis, Adhesion Molecules, and Inflammation in Type 2 Diabetes Mellitus: Correlation with Glycemic Control

2020 ◽  
Vol 17 (1) ◽  
pp. 300 ◽  
Author(s):  
Eleonora Palella ◽  
Rossella Cimino ◽  
Salvatore A. Pullano ◽  
Antonino S. Fiorillo ◽  
Elio Gulletta ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Glycemic Control ◽  
Adhesion Molecules ◽  
Adhesion Molecule ◽  
Vascular Complications ◽  
Poor Glycemic Control ◽  
Pai 1

Background: Type 2 diabetes mellitus (T2DM) is characterized by a prothrombotic state, predisposing to vascular complications. Some related markers, linking thrombophilia to hemostasis and inflammation, however, have been poorly explored in relation to patients’ glycemia. We therefore investigated the association of laboratory hemostatic parameters, circulating adhesion molecules (ADMs), white blood cell (WBC) count, and neutrophil/lymphocyte ratio (NLR) with T2DM and glycemic control. Research design: In this study, 82 subjects, grouped into T2DM patients (n = 41) and healthy individuals (n = 41) were enrolled. To evaluate glycemic control, the T2DM cohort was expanded to 133 patients and sub-classified according to glycated hemoglobin (HbA1c) <7% and ≥ 7% (n = 58 and n = 75, respectively). We assessed glycemia, HbA1c, prothrombin time (PT), activated partial thromboplastin time (aPTT), fibrinogen, plasminogen activator inhibitor-1 (PAI-1), platelet and leukocyte parameters, vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), and selectins (E-, P-, L-). Results: PT % activity, PAI-1, VCAM-1, WBC, and neutrophil counts were significantly higher in T2DM patients than in healthy subjects. Poor glycemic control (HbA1c ≥ 7%) was correlated with increased PT activity (p = 0.015), and higher levels of E-selectin (p = 0.009), P-selectin (p = 0.012), and NLR (p = 0.019). Conclusions: Both T2DM and poor glycemic control affect some parameters of hemostasis, inflammation, and adhesion molecules. Further studies are needed to establish their clinical utility as adjuvant markers for cardio-vascular risk in T2DM patients.

Diabetes mellitus and poor glycemic control increase the occurrence of coronal and root caries: a systematic review and meta-analysis

2020 ◽  
Vol 24 (11) ◽  
pp. 3801-3812
Author(s):  
Ana Karolina Almeida de Lima ◽  
Juliana Amorim dos Santos ◽  
Cristine Miron Stefani ◽  
Adriano de Almeida de Lima ◽  
Nailê Damé-Teixeira
Keyword(s):  
Diabetes Mellitus ◽  
Systematic Review ◽  
Glycemic Control ◽  
Meta Analysis ◽  
Poor Glycemic Control ◽  
Root Caries

GI symptoms in diabetes mellitus are associated with both poor glycemic control and diabetic complications

2002 ◽  
Vol 97 (3) ◽  
pp. 604-611 ◽  
Author(s):  
Peter Bytzer ◽  
Nicholas J. Talley ◽  
Johann Hammer ◽  
Lisa J. Young ◽  
Michael P. Jones ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Glycemic Control ◽  
Diabetic Complications ◽  
Poor Glycemic Control ◽  
Gi Symptoms
Sign in / Sign up

Export Citation Format

Share Document