Weight Threshold and Blood Pressure in a Lean Black Population

Hypertension ◽  
1995 ◽  
Vol 26 (4) ◽  
pp. 616-623 ◽  
Author(s):  
Clareann H. Bunker ◽  
Flora A. Ukoli ◽  
Karen A. Matthews ◽  
Andrea M. Kriska ◽  
Sara L. Huston ◽  
...  
Author(s):  
Marianne Alberts ◽  
Petter Urdal ◽  
Krisela Steyn ◽  
Inger Stensvold ◽  
Aage Tverdal ◽  
...  

Background To determine the prevalence and associated risk factors of cardiovascular diseases in a rural adult black population from Limpopo Province in South Africa. Design A cross-sectional study. Methods A sample of 1608 women and 498 men aged 30 years and above participated in the study. Sociodemographic data, anthropometric measures (body mass index, waist/hip ratio), blood pressure and biochemical risk factors were measured. A global cardiovascular disease (CVD) risk profile was developed. Results There was a high prevalence of tobacco use for men (57%) and women (35.4%), with women (28.1%) predominantly using smokeless tobacco. Alcohol use was very common in men (57.2%). Women weighed a great deal more than men, and 51.7% were either overweight or obese. Diabetes was diagnosed in 8.8 and 8.5% of women and men, respectively. High-density lipoprotein-cholesterol was relatively high, whereas 42.3% of women and 28.5% of men had low-density lipoprotein-cholesterol levels of 3 mmol/l or more. Hypertension (blood pressure ≥ 140/90 mmHg) was found in 25.5% of women and 21.6% of men. According to the Framingham formulae, 18.9% of women and 32.1% of men had a 20% or higher chance of having a CVD event in the next 10 years. Conclusions There was a high prevalence of chronic disease risk factors in the rural, poor black community in Limpopo, South Africa. Consequently, the population had a higher than expected risk of developing a CVD event in the following 10 years when compared with similar studies in black Africans.


2017 ◽  
Vol 158 (11) ◽  
pp. 403-408 ◽  
Author(s):  
Viktor László Nagy

Abstract: The diuretics are essential medicaments of antihypertensive therapy. They reduce blood pressure and cardiovascular events optimally. With increasing doses of thiazides and thiazide analogs do not come further powerful effect of reducing blood pressure or cardiovascular mortality and morbidity, but clearly elevate the side effects. Because of it, the minimum effective dose level and the fixed-dose combination therapy should be preferred. The use these drugs leads to especially positive outcome in elder patients, isolated systolic hypertension, heart failure, after stroke and in black population. Loop diuretics as antihypertensive therapy can be used only by renal impairment. The use of aldosterone antagonists can have a good effect not only on heart failure but also on prevention of atrial fibrillation. Furthermore, using it in a combination therapy with thiazides, it reduces the risk of hypokalemia. Therefore, the diuretic treatment in hypertension is flourishing again. Orv. Hetil., 2017, 158(11), 403–408.


2019 ◽  
Vol 30 (3) ◽  
pp. 146-150 ◽  
Author(s):  
Peter M Mphekgwana ◽  
Herbert M Makgopa ◽  
Kotsedi Dan Monyeki ◽  
Johanna M Malatji ◽  
Thembinkosi E Mabila

1986 ◽  
Vol 15 (3) ◽  
pp. 232-243 ◽  
Author(s):  
Lucile L. Adams ◽  
Ronald E. LaPorte ◽  
Karen A. Matthews ◽  
Trevor J. Orchard ◽  
Lewis H. Kuller

2021 ◽  
Author(s):  
Arturo Martí-Carvajal ◽  
Eduardo Alegría ◽  
Andrea Correa ◽  
Cristina Martí-Amarista ◽  
Mohamed Abd El Aziz ◽  
...  

Abstract Background The overall mortality attributable to cardiovascular diseases (coronary heart disease, sudden cardiac death/sudden cardiac arrest, stroke/transient ischemic attack, and peripheral arterial disease) is higher in the Black population when compared to the White population. Essential hypertension (EH) is the most important modifiable risk factor for cardiovascular diseases. The prevalence of hypertension among Black adults is also higher. Diuretics are antihypertensive drugs, and their role in the primary prevention of clinical cardiovascular outcomes in the Black population with essential hypertension remains unknown. To assess the clinical benefits and harms of diuretics, as a primary prevention approach, compared with placebo or any other antihypertensive medications.MethodsWe will search the Cochrane Central Register of Controlled Trials (to update), OVID MEDLINE (1946 to update), Embase (1980 to update), LILACS (1986 to update), and Web of Science (to update). We will manually search the reference lists of the included papers and contact researchers in the field. There will be no language restrictions in the search. We will include parallel-design and crossover randomized clinical trials that has adult Black people with essential hypertension as the population. The primary outcomes are all-cause mortality, myocardial infarction, stroke, and serious adverse events. Pregnant women will be excluded from the study. We will perform study selection, risk of bias assessment, and data extraction in duplicate. We will estimate risk ratios (RRs) with a 95% confidence interval (95% CI) for dichotomous outcomes. For continuous outcomes, such as health-related quality of life, systolic blood pressure, and diastolic blood pressure, we will calculate the mean difference with 95% CI or the standardized mean difference with 95% CI. We will measure statistical heterogeneity using the I² statistic and use a fixed-effects and random-effects model. We will conduct a sequential trial analysis. DiscussionOur aim is to provide external validity and try to solve conflicts about the evidence regarding use of diuretics as a primary prevention of cardiovascular outcomes in Black people with essential hypertension to guide appropriate clinical practice.Systematic review registration PROSPERO registration number: CRD42021240864


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