Clinical and Histologic Evaluations of Porcine-Derived Collagen Matrix Membrane Used for Vertical Soft Tissue Augmentation: A Case Series

2019 ◽  
Vol 39 (3) ◽  
pp. 341-347 ◽  
Author(s):  
Algirdas Puisys ◽  
Saulius Zukauskas ◽  
Ricardas Kubilius ◽  
Mike Barbeck ◽  
Dainius Razukevičius ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Case Series ◽  
Collagen Matrix ◽  
Soft Tissue Augmentation ◽  
Tissue Augmentation

Use of Collagen Matrix Scaffolds as a Substitute for Soft Tissue Augmentation: Case Series

2020 ◽  
Vol 10 (1) ◽  
pp. 10-15
Author(s):  
Najib Ghadri ◽  
Rania Livada ◽  
Vrushali Abhyankar ◽  
Les H. Binkley ◽  
Paul S. Bland ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Case Series ◽  
Collagen Matrix ◽  
Soft Tissue Augmentation ◽  
Tissue Augmentation

scholarly journals Tissue Response to a Porous Collagen Matrix Used for Soft Tissue Augmentation

Materials ◽  
2019 ◽  
Vol 12 (22) ◽  
pp. 3721 ◽  
Author(s):  
Jordi Caballé-Serrano ◽  
Sophia Zhang ◽  
Luca Ferrantino ◽  
Massimo Simion ◽  
Vivianne Chappuis ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Blood Vessels ◽  
Collagen Matrix ◽  
Giant Cells ◽  
Tissue Response ◽  
Soft Tissue Augmentation ◽  
Proliferating Cells ◽  
Tissue Integration ◽  
Inflammatory Phase ◽  
Tissue Augmentation

A short inflammatory phase and fast ingrowth of blood vessels and mesenchymal cells are essential for tissue integration of a biomaterial. Macrophages play a key role in this process. We investigated invasion of macrophages, blood vessels, and proliferating cells into a highly porous and volume-stable collagen matrix (VCMX) used for soft tissue augmentation around teeth and dental implants. The biomaterial was implanted in submucosal pouches in the canine maxilla, and the tissue response was analyzed at six different time points. Immunohistochemistry was done for proliferating cells (PCNA), macrophages (MAC387), multinucleated giant cells (CD86), and blood vessels (TGM2). Blood rapidly filled the VCMX pores. During the first week, MAC387+ cells populated the VCMX pores, blood vessels and PCNA+ cells invaded the VCMX, and CD86+ scattered cells were observed. At 15 days, MAC387+ cells were scanty, blood vessels had completely invaded the VCMX, the number of proliferating cells peaked, and fibroblasts appeared. At 30 days, MAC387+ were absent, the numbers of proliferating and CD86+ cells had declined, while blood vessel and fibroblast numbers were high. At 90 days, residual VCMX was well-integrated in soft connective tissue. In conclusion, the VCMX elicited a short inflammatory phase followed by rapid tissue integration.

Tissue Integration of a Volume-Stable Collagen Matrix in an Experimental Soft Tissue Augmentation Model

2016 ◽  
Vol 36 (6) ◽  
pp. 807-815 ◽  
Author(s):  
Luca Ferrantino ◽  
Dieter Bosshardt ◽  
Myron Nevins ◽  
Giacomo Santoro ◽  
Massimo Simion ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Collagen Matrix ◽  
Soft Tissue Augmentation ◽  
Tissue Integration ◽  
Tissue Augmentation
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