Microvessel Density Evaluation of the Effect of Enamel Matrix Derivative on Soft Tissue After Implant Placement: A Preliminary Study

2017 ◽  
Vol 35 (5) ◽  
pp. 733-738 ◽  
Author(s):  
George Guimarães ◽  
Vera de Araújo ◽  
James Nery ◽  
Daiane Peruzzo ◽  
Andresa Soares
Keyword(s):  
Soft Tissue ◽  
Microvessel Density ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Implant Placement ◽  
Density Evaluation ◽  
Preliminary Study ◽  
Matrix Derivative

scholarly journals The Applications of Enamel Matrix Derivative in Implant Dentistry: A Narrative Review

Materials ◽  
2021 ◽  
Vol 14 (11) ◽  
pp. 3045
Author(s):  
Alice Alberti ◽  
Luca Francetti ◽  
Silvio Taschieri ◽  
Stefano Corbella
Keyword(s):  
Clinical Trials ◽  
Bone Regeneration ◽  
Randomized Clinical Trials ◽  
Periodontal Regeneration ◽  
Case Series ◽  
Titanium Implants ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Implant Placement ◽  
Matrix Derivative

Enamel matrix derivative (EMD) has been successfully used for periodontal regeneration in intrabony defects. Recently, its use for peri-implant bone regeneration has also been hypothesized. The aim of this paper is to review preclinical and clinical studies investigating the use of EMD in correspondence with titanium implants, alone or as an adjunct to other biomaterials. Clinical trials and case series with more than five cases were included. Seven in vitro studies evaluated the effect of EMD, placed on titanium surfaces: An increase in proliferation and viability of osteoblasts was observed in all but two studies. An increase in TGF-β1 and osteocalcin production, alkaline phosphatase activity, and angiogenesis was also reported. Nine animal studies investigated the use of EMD at implant placement or for bone regeneration of peri-implant bone defects, and some of them reported a significant increase in bone formation or bone-to-implant contact. In four of eleven clinical trials on humans, EMD was successfully used at implant placement. The other seven evaluated the use of EMD in protocols for the treatment of peri-implantitis. In conclusion, the results of EMD seem promising, but further randomized clinical trials are needed to evaluate its efficacy.

Enamel Matrix Derivative: An effective regenerative modality (A Literature Review)

2012 ◽  
Vol 2 (7) ◽  
pp. 323-325
Author(s):  
Dr. Ranjit Singh Uppal ◽  
◽  
Dr. Atamjit Singh Dr. Atamjit Singh ◽  
Dr. Rajbir Kaur ◽  
Dr. Navdeep Kaur Sodhi
Keyword(s):  
Literature Review ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Matrix Derivative

scholarly journals Flapless application of enamel matrix derivative in periodontal retreatment: A multicenter randomized feasibility trial

2021 ◽  
Author(s):  
Holger F.R. Jentsch ◽  
Mario Roccuzzo ◽  
Andrea Pilloni ◽  
Adrian Kasaj ◽  
Rolf Fimmers ◽  
...  
Keyword(s):  
Feasibility Trial ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Matrix Derivative
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