A Retrospective Cohort Study of the Survival Rate of 88 Zygomatic Implants Placed Over an 18-year Period

Background: There is currently lack of knowledge about survival trend analysis of thalassemia patients. Therefore, the aim of the present study was to assess 5-, 10-, 20-, and 30-year survival of thalassemia patients over a 20-year time period. Methods: In this retrospective cohort study, we analysed the data of 982 beta-thalassemia patients in Iran. Birth cohort and traditional cohort analyses were used to obtain the 5-, 10-, 20-, and 30-year survival rates in various time intervals between 1995 and 2016.Results: Five and 10-year survival rates remained unchanged since 1995-2016. Overall, 20- and 30-year survival rates were lower in younger birth cohorts than older ones. A declining trend was found in 20-year survival rate from 1995 to 2000 for all and also for thalassemia major patients, but was stable from 2001 to 2016. In addition, there was a declining trend in 30-year survival rate from 1995 to 2008 for all and also for thalassemia major patients, but was an increased trend from 2009 to 2016. Conclusion: Over the past two decades and in recent birth cohorts, the 20- and 30-year survival rates has declined. In other words, declining survival trends in the birth cohorts may be associated with some different causes of mortality such as exposure to the toxic effects of iron over time and the occurrence of diseaserelated mortality.

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A Retrospective Cohort Study of the Cumulative Survival Rate of Obturator Prostheses for Marsupialization

Journal of Prosthodontics ◽

10.1111/jopr.12652 ◽

2017 ◽

Vol 28 (2) ◽

pp. e811-e816 ◽

Cited By ~ 1

Author(s):

Mamoru Murakami ◽

Yasuhiro Nishi ◽

Misaki Nishio ◽

Yoko Minemoto ◽

Takaharu Shimizu ◽

...

Keyword(s):

Cohort Study ◽

Survival Rate ◽

Retrospective Cohort Study ◽

Retrospective Cohort ◽

Cumulative Survival Rate ◽

Cumulative Survival

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Continuous Blood purification on Influenza-Associated Neurological Disease in children: a retrospective cohort study

BMC Infectious Diseases ◽

10.1186/s12879-021-06265-7 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Jingwen Ni ◽

Kenan Fang ◽

Zhe Zhao ◽

Zhiyuan Wang ◽

Qian Huang ◽

...

Keyword(s):

Cohort Study ◽

Intensive Care ◽

Survival Rate ◽

Retrospective Cohort Study ◽

Neurological Disease ◽

Retrospective Cohort ◽

Blood Purification ◽

Parental Consent ◽

Significant Difference ◽

Continuous Blood Purification

Abstract Background Due to lack of proven therapies, we evaluated the effect of CBP on Influenza-Associated Neurological Disease in children. Methods A single-center, retrospective, cohort study was conducted in Luoyang, Henan province, China from January 2018 to January 2020. Children (<18 years) with influenza-associated neurological disease were enrolled in the study. Children with indications for CBP and parental consent received CBP (Continuous Blood purification), while others received maximal intensive care treatment because of the absence of parental consent. The outcomes of the CBP and non-CBP groups were compared. Categorical variables were presented as percentage and compared by Chi-square test. Continuous variables were expressed as median (interquartile ranges) and compared with non-parametric independent sample test. Statistical analyses were carried out by SPSS (version 26.0) and p < 0.05 (2 tailed) was considered to be statistically significant. Results 30 children with influenza-associated neurological disease were recruited to the study. 18 received CBP and the other 12 received maximal intensive care. There were no differences between CBP and non-CBP children in age, sex, body weight, type of influenza virus, neurological complications, Glasgow score, PIM-2 score and PCIS at admission (p > 0.05). The inflammatory factors (CRP, PCT and IL-6) of 30 cases were tested at admission and after 3 days of admission. In the CBP group, there was a significant decrease in IL-6 levels at 3 days of admission (p = 0.003) and a decrease in CRP and PCT levels, but no significant difference (p > 0.05). In the non-CBP group, there were no significant difference on levels of CRP, PCT and IL-6 at admission and 3-day of admission (p > 0.05). The 28-day mortality was significantly lower in the CBP group compared with the non-CBP group (11.11% vs. 50%, p = 0.034). Conclusions CBP definitely reduces IL-6 levels significantly. We did find that the survival rate of patients in the CBP group was improved. But we don’t know if there is a relationship between the reduction of IL-6 levels and the survival rate. Trial registration: http://www.chictr.org.cn/index.aspx(ChiCTR2000031754).

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