Preparation of Thermoplastic Poly(L-Lactic Acid) Membranes for Guided Bone Regeneration

2013 ◽  
Vol 28 (4) ◽  
pp. 973-981 ◽  
Author(s):  
Kazunari Asano ◽  
Tomonori Matsuno ◽  
Yasuhiko Tabata ◽  
Tazuko Satoh
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Guided Bone Regeneration

scholarly journals Fabrication and evaluation of poly(lactic acid), chitosan, and tricalcium phosphate biocomposites for guided bone regeneration

2018 ◽  
Vol 135 (39) ◽  
pp. 46692 ◽  
Author(s):  
Srikanthan Ramesh ◽  
Lisa Lungaro ◽  
Dimitrios Tsikritsis ◽  
Eric Weflen ◽  
Iris V. Rivero ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Tricalcium Phosphate ◽  
Guided Bone Regeneration ◽  
Poly Lactic Acid

Preparation of electrospun siloxane-poly(lactic acid)-vaterite hybrid fibrous membranes for guided bone regeneration

2010 ◽  
Vol 70 (13) ◽  
pp. 1889-1893 ◽  
Author(s):  
Takashi Wakita ◽  
Akiko Obata ◽  
Gowsihan Poologasundarampillai ◽  
Julian R. Jones ◽  
Toshihiro Kasuga
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Poly Lactic Acid ◽  
Fibrous Membranes

Hydrophilized polycaprolactone nanofiber mesh-embedded poly(glycolic-co-lactic acid) membrane for effective guided bone regeneration

2009 ◽  
Vol 91A (2) ◽  
pp. 400-407 ◽  
Author(s):  
Wan Jin Cho ◽  
Jun Ho Kim ◽  
Se Heang Oh ◽  
Hyun Hee Nam ◽  
Jin Man Kim ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Nanofiber Mesh

scholarly journals Guided bone regeneration using a hydrophilic membrane made of unsintered hydroxyapatite and poly(L-lactic acid) in a rat bone-defect model

2018 ◽  
Vol 37 (6) ◽  
pp. 912-918 ◽  
Author(s):  
Reo IKUMI ◽  
Takayuki MIYAHARA ◽  
Norio AKINO ◽  
Noriko TACHIKAWA ◽  
Shohei KASUGAI
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Bone Defect ◽  
Guided Bone Regeneration ◽  
Defect Model ◽  
Hydrophilic Membrane ◽  
Rat Bone

Strong and biocompatible poly(lactic acid) membrane enhanced by Ti3C2Tz (MXene) nanosheets for Guided bone regeneration

2018 ◽  
Vol 229 ◽  
pp. 114-117 ◽  
Author(s):  
Ke Chen ◽  
Youhu Chen ◽  
Qihuang Deng ◽  
Seol-Ha Jeong ◽  
Tae-Sik Jang ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Poly Lactic Acid

scholarly journals Cellular compatibility of a gamma-irradiated modified siloxane-poly(lactic acid)-calcium carbonate hybrid membrane for guided bone regeneration

2011 ◽  
Vol 30 (5) ◽  
pp. 730-738 ◽  
Author(s):  
Naoshi TAKEUCHI ◽  
Miho MACHIGASHIRA ◽  
Daisuke YAMASHITA ◽  
Yoshinori SHIRAKATA ◽  
Toshihiro KASUGA ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Calcium Carbonate ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Hybrid Membrane ◽  
Poly Lactic Acid ◽  
Gamma Irradiated

scholarly journals Antibacterial Evaluation of Lithium-Loaded Nanofibrous Poly(L-Lactic Acid) Membranes Fabricated via an Electrospinning Strategy

2021 ◽  
Vol 9 ◽  
Author(s):  
Chaoan Liang ◽  
Qiming Jiang ◽  
Yi Yu ◽  
Tao Xu ◽  
Hanyu Sun ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Antibacterial Activity ◽  
Lactic Acid ◽  
Bone Regeneration ◽  
Bacterial Adhesion ◽  
Inhibition Zone ◽  
Guided Bone Regeneration ◽  
Antibacterial Effects ◽  
Measuring Device ◽  
X Ray

Lithium (Li) reportedly has anti-bacterial properties. Thus, it is an ideal option to modify barrier membranes used for guided bone regeneration to inhibit the bacterial adhesion. The aims of this study were to fabricate and characterize nanofibrous poly(L-lactic acid) (PLLA) membranes containing Li, and investigate their antibacterial effects on Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans in vitro. Li (5%Li, 10%Li, and 15%Li)-loaded nanofibrous PLLA membranes were fabricated using an electrospinning technique, and characterized via scanning electron microscopy, X-ray photoelectron spectroscopy, X-ray diffraction, a contact angle measuring device, and a universal testing machine. Sustained release of Li ions was measured over a 14-day period and biocompatibility of the Li-PLLA membranes was investigated. Evaluation of bacterial adhesion and antibacterial activity were conducted by bacterial colony counting, LIVE/DEAD staining and inhibition zone method using P.gingivalis and A.actinomycetemcomitans. Of the three Li-loaded membranes assessed, the 10%Li-PLLA membrane had the best mechanical properties and biocompatibility. Adhesion of both P.gingivalis and A.actinomycetemcomitans on Li-PLLA membranes was significantly lower than adhesion on pure PLLA membranes, particularly with regard to the 10%Li and 15%Li membranes. Significant antibacterial activity of Li-PLLA were also observed against according to the inhibition zone test. Given their better mechanical properties, biocompatibility, and antibacterial activity, PLLAs with 10%Li are a better choice for future clinical utilization. The pronounced antibacterial effects of Li-loaded PLLA membranes sets the stage for further application in guided bone regeneration.

Sign in / Sign up

Export Citation Format

Share Document