In Vitro Evaluation of the Marginal and Internal Accuracy of Different Types of Dental Ceramic Restorations Fabricated Based on Digital and Conventional Impressions

2021 ◽  
pp. 61-69
Author(s):  
Halis Özsürmeli ◽  
Şebnem Türker
Keyword(s):  
In Vitro Evaluation ◽  
Dental Ceramic ◽  
Different Types ◽  
Ceramic Restorations

scholarly journals Formulation and In vitro Evaluation of Piroxicam Conventional and Hollow Suppositories

2020 ◽  
Vol 10 (02) ◽  
pp. 200-209
Author(s):  
Entidhar Jasim Al-Akkam ◽  
Laila Abdulhussein Alwan
Keyword(s):  
Physical Properties ◽  
Polyethylene Glycols ◽  
Melting Time ◽  
Dissolution Profile ◽  
In Vitro Evaluation ◽  
Factors Affecting ◽  
Rapid Release ◽  
Solution Form ◽  
Different Types

Objective: The objective of this study was to develop higher and rapid release of piroxicam from suppositories of different types (conventional and hollow) using different bases. Methods: Thirteen formulas (F1–F13) were prepared (five were conventional, and the rest were hollow type suppositories) by using different bases, such as, witepsol H35, polyethylene glycols (PEGs) with different ratio and glycerinated gelatin. The prepared suppositories were evaluated for physical properties, such as, hardness, melting time, softening time, and for dissolution profile. Results: All of the prepared suppositories had acceptable physical properties. The maximum percent release of piroxicam was 98, 97, 95, and 91% within 50 minutes were obtained from hollow type suppositories containing piroxicam in a solution form and utilizing witepsol H35 base (F10), glycerinated gelatin base (F13), PEGs 400:4000 (70:30) (F12), and PEGs 200:6000 (70:30) (F11), respectively. Also, they exhibited rapid release of piroxicam, however, F10 and F12 released 65 and 50% of piroxicam within 5 minutes, while, F11 released 57% within 10 minutes. Conclusion: Hollow type suppositories containing piroxicam in a solution form can be considered as the most suitable formulas (F10–F13). So, hollow-type suppository is useful as a promising approach for enhancing the release of piroxicam to be administered rectally. Also, the study revealed that in addition to the type of suppositories, the type of the base, the grade, and the ratio of PEGs bases are other important factors affecting the physical properties of suppositories and the dissolution profile of piroxicam.

scholarly journals In vitro evaluation of marginal and internal adaptation of class II CAD/CAM ceramic restorations with different resinous bases and interface treatments

2015 ◽  
Vol 19 (9) ◽  
pp. 2167-2177 ◽  
Author(s):  
María José Sandoval ◽  
Giovanni Tommaso Rocca ◽  
Ivo Krejci ◽  
Michael Mandikos ◽  
Didier Dietschi
Keyword(s):  
Class Ii ◽  
In Vitro Evaluation ◽  
Cad Cam ◽  
Internal Adaptation ◽  
Ceramic Restorations

In vitro evaluation of marginal, axial, and occlusal discrepancies in metal ceramic restorations produced with new technologies

2016 ◽  
Vol 116 (3) ◽  
pp. 368-374 ◽  
Author(s):  
Hasan Kocaağaoğlu ◽  
Halil İbrahim Kılınç ◽  
Haydar Albayrak ◽  
Meryem Kara
Keyword(s):  
New Technologies ◽  
In Vitro Evaluation ◽  
Metal Ceramic ◽  
Ceramic Restorations

scholarly journals FORMULATION AND IN VITRO EVALUATION OF PIROXICAM CONVENTIONAL AND HOLLOW SUPPOSITORIES

2019 ◽  
pp. 63-71
Author(s):  
Laila Abduk Hussein Alwan ◽  
Antidhar Jasim Al.akkam
Keyword(s):  
Physical Properties ◽  
Polyethylene Glycols ◽  
Melting Time ◽  
Dissolution Profile ◽  
In Vitro Evaluation ◽  
Factors Affecting ◽  
Rapid Release ◽  
Solution Form ◽  
Different Types

Objective: The objective of this study was to develop higher and rapid release of piroxicam from suppositories of different types (conventional and hallow) using different bases. Methods: Thirteen formulas (F1–F13) were prepared (five conventional and the rest were hollow type suppositories) by using different bases such as witepsol H35, polyethylene glycols (PEGs) with different ratio and glycerinated gelatin. The prepared suppositories were evaluated for physical properties such as hardness, melting time, softening time and for dissolution profiles. Results: All of the prepared suppositories had acceptable physical properties. The maximum percent release of piroxicam was 98%, 97%, 95% and 91% within 50 min were obtained from hollow type suppositories containing piroxicam in a solution form and utilizing witepsol H35 base (F10), glycerinated gelatin base (F13), PEGs 400:4000 (70:30) (F12) and PEGs 200:6000 (70:30) (F11), respectively. Also, they exhibited rapid release of piroxicam however, F10 and F12 released 65% and 50% of piroxicam within 5 min while, F11 released 57% within 10 min. Conclusion: Hollow type suppositories containing piroxicam in a solution form can be considered as the most suitable formulas (F10–F13). So that, the hollow-type suppository is useful as a promising approach for enhancing the release of piroxicam to be administered rectally. Also, the study revealed that in addition to the type of suppositories, the type of the base, the grade and the ratio of PEGs bases are other important factors affecting the physical properties of suppositories and the dissolution profile of piroxicam.

scholarly journals In vitro evaluation of Ciprofloxacin Hydrochloride

2015 ◽  
Vol 50 (4) ◽  
pp. 251-256 ◽  
Author(s):  
M Jaman ◽  
AA Chowdhury ◽  
AA Rana ◽  
SM Masum ◽  
T Ferdous ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Pharmaceutical Products ◽  
Content Uniformity ◽  
Therapeutic Activity ◽  
Disintegration Time ◽  
In Vitro Evaluation ◽  
Average Hardness ◽  
Weight Variation ◽  
Different Types

The in vitro evaluation of the physical characteristics of the pharmaceutical products ensures their quality as well as bioavailability and impart optimum therapeutic activity. Ciprofloxacin HCl, a widely used antibiotic to treat different types of bacterial infections, was chosen for this in vitro comparative study of different pharmaceutical company. The present study compared the content uniformity, weight variation, hardness, friability, thickness, diameter, disintegration and dissolution ability of five brands of ciprofloxacin HCl tablets marketed in Bangladesh to confirm whether they follow USP guidelines. All five brands of ciprofloxacin HCl tested meet the specification of the USP for content uniformity, weight variation, hardness, friability, thickness, diameter, disintegration and dissolution. The amount of active ciprofloxacin HCl varies from 244.46 mg to 248.46 mg among the products. The average hardness and friability of the products varies 73.9 N to 77.6 N and 0.013% to 0.031%, respectively. All the brands had shown disintegration time 5 to 8 minutes while they showed 80 to 95 % release of active ingredient within 30 minutes in dissolution testing. This may confirm the absorption of the drug from gastrointestinal tract for optimum therapeutic effect.Bangladesh J. Sci. Ind. Res. 50(4), 251-256, 2015

Sign in / Sign up

Export Citation Format

Share Document