scholarly journals Acute Herpes Simplex Esophagitis in an Immunocompetent Adult with Eosinophilic Esophagitis

2021 ◽  
pp. 1003-1007
Author(s):  
Thomas Adam Wichelmann ◽  
Ryan T. Hoff ◽  
Dean N. Silas
Keyword(s):  
Herpes Simplex ◽  
Eosinophilic Esophagitis ◽  
Rare Entity ◽  
Immunocompetent Adult ◽  
Rare Association ◽  
Increased Risk ◽  
Immunocompetent Patients

Herpes simplex esophagitis (HSE) represents a rare entity in immunocompetent patients and has infrequently been described in association with eosinophilic esophagitis (EoE). Causality in this rare association remains a debated topic. We present a case of HSE occurring in an immunocompetent adult with EoE and review the literature in support of EoE induced mucosal disruption predisposing to increased risk of HSE.

Herpes Simplex Esophagitis in Immunocompetent Patients: A Rare Entity

2018 ◽  
Vol 113 (Supplement) ◽  
pp. S1024
Author(s):  
Hafez Mohammad Abdullah ◽  
Waqas Ullah ◽  
Waseem Amjad ◽  
Faisal Inayat
Keyword(s):  
Herpes Simplex ◽  
Rare Entity ◽  
Immunocompetent Patients

Sepsis and hepatitis caused by Herpes Simplex esophagitis in an immunocompetent adult

2011 ◽  
Vol 49 (05) ◽  
Author(s):  
M Dobra ◽  
L Tiszlavicz ◽  
T Wittmann ◽  
L Czakó
Keyword(s):  
Herpes Simplex ◽  
Immunocompetent Adult

Herpes Zoster with Cutaneous Dissemination in a Patient 21 Years after Splenectomy for Idiopathic Thrombocytopenic Purpura

2012 ◽  
Vol 16 (5) ◽  
pp. 368-371 ◽  
Author(s):  
Rachel A. Moquete ◽  
Barry Hartman ◽  
Richard D. Granstein
Keyword(s):  
Herpes Zoster ◽  
Herpes Simplex ◽  
Idiopathic Thrombocytopenic Purpura ◽  
Good Health ◽  
Immunocompetent Patient ◽  
Thrombocytopenic Purpura ◽  
Virus Family ◽  
Varicella Zoster ◽  
Increased Risk ◽  
History Of

Background: Varicella-zoster virus is a member of the herpes virus family that causes varicella during a primary infection and herpes zoster (HZ) when reactivated. Patients who are immunocompromised often have atypical presentations of HZ and experience complications such as multidermal involvement and dissemination. Objective: We report a case of disseminated HZ in an immunocompetent patient with a history of splenectomy for idiopathic thrombocytopenic purpura (ITP). Our 46-year-old female patient presented with a painful vesiculopapular dermatomal rash with approximately 80 other lesions diffusely spread over her body. She was in good health but had a splenectomy for ITP 21 years earlier and a history of recurrent herpes labialis. The latter led to the tentative diagnosis of a widespread herpes simplex infection. However, laboratory results confirmed a diagnosis of disseminated herpes zoster. A workup of the patient's immune status did not reveal any abnormalities other than the patient's previously noted splenectomy. Conclusions: This case adds to the two reports of patients developing cutaneous disseminated HZ several years after splenectomy. Our case serves as a reminder that patients with a history of splenectomy appear to be at increased risk for cutaneous dissemination of HZ. Renseignements de base: Le virus varicelle-zona est un virus de la famille des Herpesviridae qui cause la varicelle durant une primo-infection, et l'herpès zoster (zona) (HZ) en cas de réactivation. Les patients qui sont immunocompromis ont souvent des présentations atypiques de HZ et affichent des complications telles que la participation et la dissémination multicutanées. Objectif: Nous exposons un cas de zona disséminé chez un patient immunocompétent ayant subi une splénectomie pour traiter un purpura thrombocytopénique idiopathique (PTI). Notre patiente âgée de 46 ans présentait une éruption vésiculo-papuleuse douloureuse localisée dans une zone dermatome avec environ 80 autres lésions diffuses réparties sur son corps. Elle était en bonne santé mais avait subi une splénectomie pour traiter un PTI 21 ans plus tôt et présentait des antécédents d'épisodes récurrents d'herpès labial. Ce dernier a abouti 'a un diagnostic provisoire d'une infection généralisée par le virus herpès simplex. Cependant, les résultats des analyses de laboratoire ont confirmé un diagnostic d'herpès zoster (zona) disséminé. Une investigation de l'état immunitaire de la patiente n'a pas révélé d'anomalies autres que la splénectomie que la patiente a subie antérieurement. Conclusions: Ce cas vient s'ajouter aux deux cas de patients signalés qui ont développé un HZ disséminé plusieurs années après avoir subi une splénectomie. Notre cas sert à rappeler que les patients présentant des antécédents de splénectomie semblent être exposés à un risque accru de dissémination cutanée sous forme de HZ.

scholarly journals Herpes simplex virus, early neuroimaging markers and incidence of Alzheimer’s disease

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Morgane Linard ◽  
Marion Baillet ◽  
Luc Letenneur ◽  
Isabelle Garrigue ◽  
Gwenaëlle Catheline ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Herpes Simplex Virus ◽  
Herpes Simplex ◽  
Diffusion Tensor ◽  
Hippocampal Volume ◽  
Potential Interaction ◽  
Increased Risk ◽  
Simplex Virus ◽  
Igg Level

AbstractWhile previous studies suggest the implication of herpes simplex virus (HSV) in the onset of Alzheimer’s disease (AD), no study has investigated its association with early neuroimaging markers of AD. In the Three-City and the AMI cohorts, the associations between HSV infection and (i) hippocampal volume (n = 349), (ii) white matter alterations in the parahippocampal cingulum and fornix using diffusion tensor imaging (n = 260), and (iii) incidence of AD (n = 1599) were assessed according to APOE4 status. Regardless of APOE4 status, infected subjects presented (i) significantly more microstructural alterations of the parahippocampal cingulum and fornix, (ii) lower hippocampal volumes only when their anti-HSV IgG level was in the highest tercile—reflecting possibly more frequent reactivations of the virus (p = 0.03 for subjects with a high anti-HSV IgG level while there was no association for all infected subjects, p = 0.19), and (iii) had no increased risk of developing AD. Nevertheless, among APOE4 carriers, infected subjects presented lower hippocampal volumes, although not significant (p = 0.09), and a two or three times higher risk of developing AD (adjusted Hazard ratio (aHR) = 2.72 [1.07–6.91] p = 0.04 for infected subjects and aHR = 3.87 [1.45–10.28] p = 0.007 for infected subjects with an anti-HSV IgG level in the highest tercile) while no association was found among APOE4 noncarriers. Our findings support an association between HSV infection and AD and a potential interaction between HSV status and APOE4. This reinforces the need to further investigate the infectious hypothesis of AD, especially the associated susceptibility factors and the possibility of preventive treatments.

scholarly journals Acute Herpes Simplex Viral Esophagitis Occurring in 5 Immunocompetent Individuals With Eosinophilic Esophagitis

2016 ◽  
Vol 3 (1) ◽  
pp. 165-168 ◽  
Author(s):  
Dorothee Zimmermann ◽  
Dominique H. Criblez ◽  
Evan S. Dellon ◽  
Christian Bussmann ◽  
David Pfeifer ◽  
...  
Keyword(s):  
Herpes Simplex ◽  
Eosinophilic Esophagitis

scholarly journals Cerebellar Cryptococcoma in an Immunocompetent Adult: A Rare Occurrence Report of a Case and Review of Literature

2020 ◽  
Vol 9 (03) ◽  
pp. 204-207
Author(s):  
Manish Kumar ◽  
Ankur Bajaj ◽  
Manoj Kumar Tewari ◽  
Paramjit Singh ◽  
Bishan Das Radotra
Keyword(s):  
Histopathological Examination ◽  
Metastatic Lesion ◽  
Immunocompetent Patient ◽  
Review Of Literature ◽  
Immunocompetent Adult ◽  
Oral Fluconazole ◽  
Antifungal Chemotherapy ◽  
Middle Aged Adult ◽  
The Brain ◽  
Immunocompetent Patients

AbstractThis study reports a rare case of cryptococcoma of the brain and review the related literature. An intracranial lesion, in a healthy, middle-aged adult who underwent surgery with a preoperative diagnosis of neoplastic/metastatic lesion, which turned out to be cryptococcoma, is being reported. Histopathological examination revealed that this immunocompetent patient had cryptococcoma of the cerebellum. He responded to antifungal chemotherapy (amphotericin B initially for 2 weeks and later oral fluconazole for 10 weeks) very well. Occurrence of cryptococcomas in immunocompetent patients is rare and responds to antifungal chemotherapy very well. Only six cases (including this) have been reported in literature till now.

scholarly journals Torsion of Undescended Third Testis, as Rare Cause of Painful Inguinal Mass

2015 ◽  
Vol 2015 ◽  
pp. 1-3 ◽  
Author(s):  
Suheil Artul ◽  
Faozi Artoul ◽  
Basel Fahoum ◽  
William Nseir ◽  
Najib Nasrallah ◽  
...  
Keyword(s):  
Rare Entity ◽  
Inguinal Mass ◽  
Increased Risk

Twenty years old young was referred to our department due to painful inguinal mass. The mass was diagnosed as torsion of third testis which was treated by orchiectomy. Polyorchidism is a rare entity with increased risk for malignancy and torsion.

scholarly journals Reactivation of Varicella Zoster Virus after Vaccination for SARS-CoV-2

Vaccines ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 572
Author(s):  
Mina Psichogiou ◽  
Michael Samarkos ◽  
Nikolaos Mikos ◽  
Angelos Hatzakis
Keyword(s):  
Adverse Event ◽  
Herpes Zoster ◽  
T Cell ◽  
Varicella Zoster Virus ◽  
Time Window ◽  
Vaccine Safety ◽  
Cell Mediated Immunity ◽  
Varicella Zoster ◽  
Increased Risk ◽  
Immunocompetent Patients

Seven immunocompetent patients aged > 50 years old presented with herpes zoster (HZ) infection in a median of 9 days (range 7–20) after vaccination against SARS-CoV-2. The occurrence of HZ within the time window 1–21 days after vaccination defined for increased risk and the reported T cell-mediated immunity involvement suggest that COVID-19 vaccination is a probable cause of HZ. These cases support the importance of continuing assessment of vaccine safety during the ongoing massive vaccination for the COVID-19 pandemic and encourage reporting and communication of any vaccination-associated adverse event.

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