scholarly journals A high dose of creatine combined with resistance training appears to be required to augment indices of bone health in older adults

2021 ◽  
Author(s):  
Scott C. Forbes ◽  
Sergej M. Ostojic ◽  
Tacito P. Souza-Junior ◽  
Darren G. Candow
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Bone Health ◽  
High Dose

Not applicable

Effects of a resistance training community programme in older adults

2021 ◽  
pp. 1-16
Author(s):  
Majid Mufaqam Syed-Abdul ◽  
Chrissa L. McClellan ◽  
Elizabeth J. Parks ◽  
Stephen D. Ball
Keyword(s):  
Older Adults ◽  
Body Mass Index ◽  
Resistance Training ◽  
Muscle Mass ◽  
Body Mass ◽  
Fat Mass ◽  
Training Programme ◽  
Haemoglobin A1c ◽  
Community Based ◽  
Resistance Training Programme

Abstract Ageing is associated with reduced muscle mass, strength, flexibility and balance, resulting in a poor quality of life (QOL). Past studies have occurred in highly controlled laboratory settings which provide strong support to determine whether similar gains can be made in community programmes. Twenty participants were enrolled in an eight-week community-based resistance training programme (mean age = 61.3 (standard error (SE) = 0.9) years); Body Mass Index = 32.0 (SE = 1.3) kg/m2). All participants completed surveys to assess outcomes associated with QOL. Given the relationship between muscle function and nerve health, nerve conduction studies (NCS) were also conducted in a separate group of participants (mean age = 64.9 (SE = 2.0) years; Body Mass Index = 32.6 (SE = 1.9) kg/m2). This community-based training programme significantly improved QOL measures in older adults (p < 0.001). Although weight loss was not the primary outcome of the study, participants reduced their body weights (p < 0.001), by primarily reducing fat mass (p = 0.007) while maintaining muscle mass. Significant improvements were observed in muscle strength (2.2%), flexibility and balance (3.2–464.2%, p ⩽ 0.05 for all). Improvements were also observed in plasma glucose (p = 0.05), haemoglobin A1C (p = 0.06) and aldolase enzyme levels (p < 0.001). Scores for surveys on memory and sleep improved (p < 0.05). Improved QOL was associated with increased lean mass (r = −0.714, p = 0.002), decreased fat mass (r = −0.702, p = 0.003) and improved flexibility and balance (r = −0.627, p = 0.008). An eight-week, community-based resistance training programme significantly improved QOL in older adults. Influence on the lipid profile and NCS still needs further investigation.

scholarly journals Intersection of Sex and Frailty in Humoral Immune Responses to Influenza Vaccine in Community-Dwelling Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 271-272
Author(s):  
Janna Shapiro ◽  
Helen Kuo ◽  
Rosemary Morgan ◽  
Huifen Li ◽  
Sabra Klein ◽  
...  
Keyword(s):  
Older Adults ◽  
Immune Responses ◽  
Influenza A ◽  
Community Dwelling ◽  
Influenza Vaccines ◽  
Health Study ◽  
Cardiovascular Health Study ◽  
High Dose ◽  
Humoral Immune ◽  
Humoral Immune Responses

Abstract Older adults bear the highest burden of severe disease and complications associated with seasonal influenza, with annual vaccination serving as the best option for protection. Variability in vaccine efficacy exists, yet the host factors that affect immune responses to inactivated influenza vaccines (IIV) are incompletely understood. We hypothesized that sex and frailty interact to affect vaccine-induced humoral responses among older adults. To test this hypothesis, community-dwelling adults above 75 years of age were recruited yearly, assessed for frailty (as defined by the Cardiovascular Health Study criteria), and vaccinated with the high-dose trivalent IIV. Humoral immune responses were evaluated via hemagglutination inhibition titers. The study began during the 2014-2015 influenza season, with yearly cohorts ranging from 76-163 individuals. A total of 617 vaccinations were delivered from 2014-2019. In preliminary analyses, the outcome of interest was seroconversion, defined as ≥ 4-fold rise in titers. Crude odds ratios suggest that females are more likely to seroconvert to influenza A strains (H1N1: OR = 1.39, (0.98-1.96) ; H3N2: 1.17 (0.85 – 1.62)), while males are more likely to seroconvert to the B strain (OR = 0.85 (0.60 – 1.22)). Furthermore, this sex difference was modified by frailty – for example, the odds of seroconversion to H1N1 were 65% higher for females than males among those who were nonfrail, and only 30% higher among females who were frail. Together, these results suggest that sex and frailty interact to impact immune responses to influenza vaccines. These findings may be leveraged to better protect vulnerable populations.

scholarly journals Associations of muscle lipid content with physical function and resistance training outcomes in older adults: altered responses with metformin

GeroScience ◽  
2021 ◽  
Author(s):  
Douglas E. Long ◽  
Bailey D. Peck ◽  
Steven C. Tuggle ◽  
Alejandro G. Villasante Tezanos ◽  
Samuel T. Windham ◽  
...  
Keyword(s):  
Older Adults ◽  
Resistance Training ◽  
Physical Function ◽  
Lipid Content ◽  
Muscle Lipid ◽  
Training Outcomes

Can Resistance Training Improve Upper Limb Postural Tremor, Force Steadiness and Dexterity in Older Adults? A Systematic Review

2019 ◽  
Vol 49 (8) ◽  
pp. 1199-1216
Author(s):  
Justin W. L. Keogh ◽  
Sinead O’Reilly ◽  
Ethan O’Brien ◽  
Steven Morrison ◽  
Justin J. Kavanagh
Keyword(s):  
Systematic Review ◽  
Older Adults ◽  
Resistance Training ◽  
Upper Limb ◽  
Postural Tremor ◽  
Force Steadiness

scholarly journals An Economic Evaluation of Resistance Training and Aerobic Training versus Balance and Toning Exercises in Older Adults with Mild Cognitive Impairment

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e63031 ◽  
Author(s):  
Jennifer C. Davis ◽  
Stirling Bryan ◽  
Carlo A. Marra ◽  
Devika Sharma ◽  
Alison Chan ◽  
...  
Keyword(s):  
Older Adults ◽  
Cognitive Impairment ◽  
Economic Evaluation ◽  
Mild Cognitive Impairment ◽  
Resistance Training ◽  
Aerobic Training

scholarly journals The Effects of an Online Theory-Based Bone Health Program for Older Adults

2015 ◽  
Vol 36 (9) ◽  
pp. 1117-1144 ◽  
Author(s):  
Eun-Shim Nahm ◽  
Barbara Resnick ◽  
Clayton Brown ◽  
Shijun Zhu ◽  
Jay Magaziner ◽  
...  
Keyword(s):  
Older Adults ◽  
Bone Health ◽  
Calcium Intake ◽  
Health Program ◽  
Outcome Expectations ◽  
Control Group ◽  
Discussion Boards ◽  
Learning Modules ◽  
Osteoporosis Knowledge ◽  
Efficacy Outcome

An estimated 10 million Americans age 50 and older have osteoporosis, and many experience associated fractures. Although several interventions have been shown to be effective in preventing osteoporosis, their impact on bone health among older adults was limited. The aim of this study was, therefore, to examine the effects of a theory-based online bone health program (Bone Power program) for a large number of older adults. The 8-week program included learning modules, discussion boards, and other resources. Participants ( N = 866; M age = 62.5 years) were recruited online and randomized into a Bone Power or control group. At the end of the intervention, the Bone Power group showed significantly greater improvement over the control group in osteoporosis knowledge, self-efficacy/outcome expectations for calcium intake and exercise, and calcium intake and exercise behaviors. This study’s findings suggest that online health programs can be effective in improving older adults’ knowledge, beliefs, and health behaviors.

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