scholarly journals Tumour-Not So Sweet, Tumour-Induced Hypoglycemia: A Rare Case of Refractory Hypoglycemia in a Toddler

2021 ◽  
pp. 1-3
Author(s):  
Jayati Joshipura ◽  
Vani H.N. ◽  
Nabanita Kora
Keyword(s):  
Islet Cell ◽  
Rare Case ◽  
Serum Insulin ◽  
Rare Complication ◽  
Abdominal Mass ◽  
Retroperitoneal Mass ◽  
Sample Analysis ◽  
C Peptide ◽  
Resource Limited ◽  
Limited Setting

Tumour-induced hypoglycaemia is a rare complication/condition mainly seen in adults. It is caused due to increased production of insulin or insulin-like growth factor (IGF) 2 tumour cells. We present a 3-year-old paediatric patient with non-islet cell tumour induced hypoglycaemia (NICTH) secondary to rhabdomyosarcoma. She presented with abdominal mass and refractory hypoglycaemia, requiring high glucose infusion and steroids. Critical sample analysis during hypoglycaemia showed suppression of insulin, IGF-1, C-peptide, growth hormone, and ketones, with a high cortisol level. CT scan of abdomen and pelvis showed a huge retroperitoneal mass, later diagnosed as rhabdomyosarcoma. In a resource-limited setting, where IGF-2 is not possible, low serum insulin and IGF-1 levels during hypoglycaemia aids in diagnosis of NICTH. This is one of the first few reported paediatric cases with NICTH from India, and we believe that reporting this case would add more information to the existing literature. Thus, NICTH should be suspected in all malignancies presenting with intractable hypoglycaemia irrespective of their age.

Maxillary Ameloblastoma With Pulmonary Metastasis: Management Challenges in Resource-Limited Setting—A Case Report

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S42-S42
Author(s):  
Salvatory Mlaga ◽  
Tupokigwe Brown ◽  
Atuganile Malango ◽  
Karpal Sohal ◽  
Edda Vuhahula
Keyword(s):  
Rare Case ◽  
Treatment Options ◽  
Resource Limited Setting ◽  
Medical Community ◽  
Biological Behavior ◽  
Ki 67 ◽  
Regional Lymph Nodes ◽  
Ct Guided ◽  
Resource Limited ◽  
Limited Setting

Abstract Introduction: Ameloblastoma is a benign odontogenic tumor that may exhibit aggressive biological behavior with local recurrence. It more commonly occurs in the mandible than the maxilla. Rarely, ameloblastoma may metastasize to local regional lymph nodes and/or distant organs, notably lungs, brain, and skin, hence the term metastasizing (malignant) ameloblastoma (MA), in keeping with the WHO definition of MA in its recent classification of odontogenic tumors (2017). Here, we report a rare case of maxillary ameloblastoma that metastasized to the lungs in a 22-year-old African male. Radiological evaluation revealed a massive maxillary tumor that had a local extension to the brain. Chest x-ray and CT scan pointed out metastatic mass to the lungs. Histology of the tumor mass revealed it to be follicular ameloblastoma with aggressive behavior shown by abnormal mitoses and further characterization by immunohistochemical reactivity to Ki-67. CT-guided fine-needle aspiration cytology of the lung mass showed microscopic features of ameloblastoma bearing resemblance to the primary jaw tumor. Socioeconomic constraints on the patient’s side and limited medical resources necessitated planning that served the purpose of proper diagnosis and treatment options. In this paper, we discuss the clinical behavior, differential diagnosis, and challenges faced by clinicians in managing metastatic ameloblastoma in a resource-limited setting. Conclusively, reporting this rare case and first of its kind in our locality raises awareness, hence reducing misdiagnosis of primary tumor in sites other than the jaw, while also sharing our experience of managing metastasizing ameloblastoma in a resource-limited setting to the larger medical community.

scholarly journals Surgical treatment of rare case of scapula osteochondroma in a resource limited setting: A case report

2019 ◽  
Vol 61 ◽  
pp. 130-134
Author(s):  
F.O. Ngongang ◽  
G. Fodjeu ◽  
A.C. Fon ◽  
L. Fonkoue ◽  
M.L. Guifo ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Rare Case ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Limited Setting

Abstract #288 Dyslipidemia in Childhood Type 1 Diabetes in India: Prevalence Correlates and Management Challenges in a Resource Limited Setting

2019 ◽  
Vol 25 ◽  
pp. 117
Author(s):  
S Chandraprabha ◽  
T Jayalakshmi ◽  
Reshma Vijay ◽  
Kavitha Muniraj ◽  
Muralidhara Krishna ◽  
...  
Keyword(s):  
Type 1 Diabetes ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Childhood Type 1 Diabetes ◽  
Childhood Type ◽  
Limited Setting

Obstacles facing gastrointestinal endoscopy in a resource-limited setting

2018 ◽  
Vol 56 (08) ◽  
pp. e354-e354
Author(s):  
A Ebigbo ◽  
M Schlander ◽  
G Anigbo ◽  
U Ijoma ◽  
H Messmann
Keyword(s):  
Gastrointestinal Endoscopy ◽  
Resource Limited Setting ◽  
Resource Limited ◽  
Limited Setting

HIV Drug Resistance Testing in a Resource Limited Setting with High Viral Diversity: The First Twenty Eight Months Experience

2017 ◽  
Vol 15 (4) ◽  
Author(s):  
Elodie Teclaire Ngo-Malabo ◽  
Paul Alain Ngoupo ◽  
Serge Alain Sadeuh-Mba ◽  
Emmanuel Akongnwi ◽  
Robert Banaï ◽  
...  
Keyword(s):  
Drug Resistance ◽  
Resource Limited Setting ◽  
Resistance Testing ◽  
Viral Diversity ◽  
Hiv Drug Resistance ◽  
Drug Resistance Testing ◽  
Resource Limited ◽  
Limited Setting
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