Aerobic Exercise Increases Vascular Diameter of Arteriovenous Fistula in Hemodialysis Patients

2021 ◽  
pp. 1-7
Author(s):  
Francini Porcher Andrade ◽  
Talmir Nolasco ◽  
Marli Maria Knorst ◽  
Paula Maria Eidt Rovedder
Keyword(s):  
Blood Pressure ◽  
Aerobic Exercise ◽  
Crossover Study ◽  
Arteriovenous Fistula ◽  
Random Order ◽  
Vessel Diameter ◽  
Hemodialysis Patients ◽  
Cycle Ergometer ◽  
Acute Effects ◽  
Randomized Crossover Study

<b><i>Introduction:</i></b> A healthy arteriovenous fistula (AVF) depends on adequate vessel diameter which can be maintained through aerobic exercises. A randomized crossover study was conducted to evaluate the acute effects of aerobic exercise on a cycle ergometer on AVF vascular diameter, through ultrasound, and on blood pressure (BP). <b><i>Methods:</i></b> Eight hemodialysis (HD) patients completed 2 different occasions in random order with a 7-day washout: (a) exercising moment, in which 30-min aerobic exercise was performed on a cycle ergometer; and (b) resting moment, which was performed 30-min with the patient sitting in a chair. Both occasions were evaluated 1-h before the second weekly HD day. <b><i>Results:</i></b> A significant increase in AVF vascular diameter induced by 30-min aerobic exercise was found (1.15 ± 0.56 to 1.47 ± 0.66 cm; <i>p</i> = 0.042), whereas systolic (<i>p</i> = 0.105) and diastolic BP (<i>p</i> = 0.366) did not change. <b><i>Conclusions:</i></b> We can conclude that acute aerobic exercise was shown to be effective in improving the AVF vascular diameter in HD patients. The aerobic exercise benefits in endothelium-dependent vasodilation which may be an effective, practical, and economic strategy to maintain AVF patency.

Cardiovascular, perceived exertion and affective responses during aerobic exercise performed with imposed and a self-selected intensity in patients with Parkinson’s disease

2021 ◽  
pp. 1-6
Author(s):  
Hélcio Kanegusuku ◽  
Marilia de Almeida Correia ◽  
Paulo Longano ◽  
Erika Okamoto ◽  
Maria Elisa Pimentel Piemonte ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Aerobic Exercise ◽  
Perceived Exertion ◽  
Exercise Adherence ◽  
Random Order ◽  
Cycle Ergometer ◽  
Affective Responses ◽  
Rating Of Perceived Exertion

BACKGROUND: Exercise with self-selected intensity (SSI) has emerged as a new strategy for exercise prescription aiming to increase exercise adherence in Parkinson’s disease (PD). OBJECTIVE: We compared the cardiovascular, perceived exertion and affective responses during traditional aerobic exercise and with SSI in PD. METHODS: Twenty patients with PD performed two aerobic exercise sessions in random order with an interval of at least 72 h between them: Traditional session (cycle ergometer, 25 min, 50 rpm) with imposed intensity (II) (60–80% maximum heart rate [HR]) and SSI: (cycle ergometer, 25 min, 50 rpm) with SSI. The HR (Polar V800 monitor), systolic blood pressure (auscultatory method), rating of perceived exertion (Borg scale 6–20) and affective responses (feeling scale) were assessed during the exercise at 8th and 18th minute. The Generalized Estimating Equation Model was used for comparison between both sessions (P <  0.05). RESULTS: The exercise intensity was not significantly different between both exercise sessions (8th minute: II –76.3±1.0 vs. SSI –76.5±1.3 % of maximal HR; 18th minute: II –78.9±0.9 vs. SSI –79.1±1.3 % of maximal HR, p = 0.93). Blood pressure, perceived exertion and affective responses were also not significantly different between both sessions (P >  0.05). CONCLUSIONS: Cardiovascular and psychophysiological responses were not different during aerobic exercise performed with II and with SSI in patients with PD.

scholarly journals Caffeine affects autonomic control of heart rate and blood pressure recovery after aerobic exercise in young adults: a crossover study

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Luana Almeida Gonzaga ◽  
Luiz Carlos Marques Vanderlei ◽  
Rayana Loch Gomes ◽  
Vitor Engrácia Valenti
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Young Adults ◽  
Aerobic Exercise ◽  
Crossover Study ◽  
Autonomic Control ◽  
Pressure Recovery

scholarly journals Combined effects of aerobic exercise and l -arginine ingestion on blood pressure in normotensive postmenopausal women: A crossover study

Life Sciences ◽  
2016 ◽  
Vol 151 ◽  
pp. 323-329 ◽  
Author(s):  
Guilherme M. Puga ◽  
Iane de P. Novais ◽  
Christos S. Katsanos ◽  
Angelina Zanesco
Keyword(s):  
Blood Pressure ◽  
Aerobic Exercise ◽  
Crossover Study ◽  
Postmenopausal Women ◽  
Combined Effects

scholarly journals Effectiveness of Dose Adjustment of Insulin in Type 2 Diabetes among Hemodialysis Patients with End-Stage Renal Disease: A Randomized Crossover Study

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Amol Singhsakul ◽  
Ouppatham Supasyndh ◽  
Bancha Satirapoj
Keyword(s):  
Type 2 Diabetes ◽  
Renal Disease ◽  
Crossover Study ◽  
End Stage Renal Disease ◽  
Hemodialysis Patients ◽  
Insulin Group ◽  
Stage Renal Disease ◽  
End Stage ◽  
Randomized Crossover Study

Determining insulin requirements for hemodialysis patients with end-stage renal disease (ESRD) is difficult. We performed a randomized crossover study among type 2 diabetes (T2DM) patients with ESRD on continuous hemodialysis and receiving standard insulin for glycemic control. The patients were randomized in 2 groups: daily insulin needed on the day after hemodialysis and a 25% decrease in daily insulin needed on the day after hemodialysis. A total of 51 T2DM patients with ESRD were enrolled. The adjusted-insulin group had higher plasma glucose levels at the 2nd hour of dialysis than those of the nonadjusted-insulin group. Incidence of hypoglycemia per dialysis session (3.3% vs. 0.7%, P=0.02) and symptoms related to hypoglycemia (6.9% vs. 0.7%, P=0.001) were more frequent in the nonadjusted-insulin group. A reduced insulin administration of 25% among T2DM patients undergoing hemodialysis on the day of dialysis was associated with sustained glycemic efficacy and the production of fewer hypoglycemic symptoms. This trial is registered with TCTR20180724002.

scholarly journals High‐Dose Glucagon Has Hemodynamic Effects Regardless of Cardiac Beta‐Adrenoceptor Blockade: A Randomized Clinical Trial

2020 ◽  
Vol 9 (21) ◽  
Author(s):  
Kasper M. Petersen ◽  
Søren Bøgevig ◽  
Troels Riis ◽  
Niklas W. Andersson ◽  
Kim P. Dalhoff ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Plasma Concentrations ◽  
Random Order ◽  
Beta Blockade ◽  
High Dose ◽  
Clinical Effects ◽  
Hemodynamic Effects ◽  
Unique Identifier ◽  
Beta Adrenoceptor ◽  
Randomized Crossover Study

Background Intravenous high‐dose glucagon is a recommended antidote against beta‐blocker poisonings, but clinical effects are unclear. We therefore investigated hemodynamic effects and safety of high‐dose glucagon with and without concomitant beta‐blockade. Methods and Results In a randomized crossover study, 10 healthy men received combinations of esmolol (1.25 mg/kg bolus+0.75 mg/kg/min infusion), glucagon (50 µg/kg), and identical volumes of saline placebo on 5 separate days in random order (saline+saline; esmolol+saline; esmolol+glucagon bolus; saline+glucagon infusion; saline+glucagon bolus). On individual days, esmolol/saline was infused from −15 to 30 minutes. Glucagon/saline was administered from 0 minutes as a 2‐minute intravenous bolus or as a 30‐minute infusion (same total glucagon dose). End points were hemodynamic and adverse effects of glucagon compared with saline. Compared with saline, glucagon bolus increased mean heart rate by 13.0 beats per minute (95% CI, 8.0–18.0; P <0.001), systolic blood pressure by 15.6 mm Hg (95% CI, 8.0–23.2; P =0.002), diastolic blood pressure by 9.4 mm Hg (95% CI, 6.3–12.6; P <0.001), and cardiac output by 18.0 % (95% CI, 9.7–26.9; P =0.003) at the 5‐minute time point on days without beta‐blockade. Similar effects of glucagon bolus occurred on days with beta‐blockade and between 15 and 30 minutes during infusion. Hemodynamic effects of glucagon thus reflected pharmacologic glucagon plasma concentrations. Glucagon‐induced nausea occurred in 80% of participants despite ondansetron pretreatment. Conclusions High‐dose glucagon boluses had significant hemodynamic effects regardless of beta‐blockade. A glucagon infusion had comparable and apparently longer‐lasting effects compared with bolus, indicating that infusion may be preferable to bolus injections. Registration Information URL: https://www.clinicaltrials.gov ; Unique identifier: NCT03533179.

scholarly journals Plasma ghrelin levels during exercise in healthy subjects and in growth hormone-deficient patients

2002 ◽  
pp. 65-70 ◽  
Author(s):  
R Dall ◽  
J Kanaley ◽  
TK Hansen ◽  
N Moller ◽  
JS Christiansen ◽  
...  
Keyword(s):  
Body Composition ◽  
Aerobic Exercise ◽  
Healthy Subjects ◽  
Peak Level ◽  
Random Order ◽  
Cycle Ergometer ◽  
Control Group ◽  
Gh Replacement ◽  
Submaximal Aerobic Exercise ◽  
Exercise Induced

OBJECTIVE: To characterise plasma levels of the recently identified endogenous ligand for the GH secretagogue receptor (ghrelin) during submaximal aerobic exercise in healthy adults and in GH-deficient adults. DESIGN: Eight healthy males (mean+/-s.e. age, 40.8+/-2.9 years) and eight hypopituitary males with verified GH deficiency (mean+/-s.e. age, 40.8+/-4.7 years) underwent a baseline test of their peak aerobic capacity (VO(2) peak) and lactate threshold (LT) on a cycle ergometer, as well as an evaluation of body composition. The patients were then studied on two occasions in random order when they exercised for 45 min at their LT. On one occasion, GH replacement had been discontinued from the evening before, whereas on the other occasion they received their evening GH in addition to an intravenous infusion of GH (0.4 IU) during exercise the following day. The healthy subjects exercised at their LT on one occasion without GH. RESULTS: The patients were significantly more obese and had lower VO(2) max (corrected for body weight) and LT as compared with the control subjects. Exercise induced a peak in serum GH concentrations after 45 min in the control group (11.43+/-3.61 microg/l). Infusion of GH in the patients resulted in a peak level after 45 min, whereas no increase was detected when exercising without GH (9.77+/-2.40 (GH) vs 0.11+/-0.07 microg/l (no GH)). Plasma ghrelin levels did not change significantly with time in either study, and no correlations were detected between ghrelin levels and parameters such as GH and IGF-I levels, age or body composition. Plasma ghrelin levels were significantly lower during the study period with GH as compared with the study with no GH. CONCLUSIONS: Submaximal aerobic exercise of an intensity sufficient to stimulate GH release was not associated with significant alterations in plasma ghrelin concentrations, which indicated that systemic ghrelin is not involved in the exercise-induced stimulation of GH secretion. The observation that ghrelin levels were lower during GH replacement suggests that GH may feedback-inhibit systemic ghrelin release.

scholarly journals Acute Effects of Nitrate-Rich Beetroot Juice on Blood Pressure, Hemostasis and Vascular Inflammation Markers in Healthy Older Adults: A Randomized, Placebo-Controlled Crossover Study

Nutrients ◽  
2017 ◽  
Vol 9 (11) ◽  
pp. 1270 ◽  
Author(s):  
Kyle Raubenheimer ◽  
Danica Hickey ◽  
Michael Leveritt ◽  
Robert Fassett ◽  
Joaquin Ortiz de Zevallos Munoz ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Older Adults ◽  
Crossover Study ◽  
Vascular Inflammation ◽  
Beetroot Juice ◽  
Acute Effects ◽  
Inflammation Markers ◽  
Healthy Older Adults
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