scholarly journals Endoscopy Capsule Retention in a Young Female with Small Bowel Strictures Secondary to Non-Steroidal Anti-Inflammatory Drugs

2021 ◽  
pp. 948-953
Author(s):  
Muhammad Umair Tayyub ◽  
Laurence Egan ◽  
Carol Goulding
Keyword(s):  
Abdominal Pain ◽  
Small Bowel ◽  
Young Female ◽  
Small Bowel Stricture ◽  
Chronic Anaemia ◽  
History Of ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Capsule Retention ◽  
Bowel Stricture

Non-steroidal anti-inflammatory drugs (NSAIDs) can cause small bowel damage, which could present in different ways, including abdominal pain and occult gastrointestinal bleeding. NSAID use can also result in small bowel strictures, which can be challenging to diagnose and manage. Here, we describe a case of a 49-year-old female who presented with chronic anaemia and intermittent abdominal pain, with a history of NSAID use. She underwent capsule endoscopy as part of the workup for anaemia and subsequently had capsule retention due to a small bowel stricture.

scholarly journals Diaphragm Disease: NSAID-Induced Small Bowel Stricture

2018 ◽  
Vol 12 (2) ◽  
pp. 327-330 ◽  
Author(s):  
Bruce J. Grattan Jr. ◽  
Tracy Bennett ◽  
Michael R. Starks
Keyword(s):  
Risk Factor ◽  
Abdominal Pain ◽  
Small Bowel ◽  
Small Bowel Obstruction ◽  
Bowel Obstruction ◽  
Small Bowel Stricture ◽  
Diaphragm Disease ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Bowel Stricture

The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is ubiquitous. However, it remains an oftentimes under-recognized risk factor for the development of strictures and small bowel obstruction. Herein we describe the case of a 63-year-old female with a prolonged course of abdominal pain and occult anemia found to have a diaphragmatic stricture in the small bowel related to chronic NSAID use.

scholarly journals Idiopathic localised dilatation of the intestine in adults

2019 ◽  
Vol 12 (8) ◽  
pp. e230443
Author(s):  
Niccolò Rotigliano ◽  
Matthias Sauter ◽  
Markus von Flüe ◽  
Daniel Christian Steinemann
Keyword(s):  
Systematic Review ◽  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Small Bowel ◽  
Gastrointestinal Bleeding ◽  
Small Bowel Obstruction ◽  
Small Bowel Stricture ◽  
Segmental Dilatation ◽  
Bowel Stricture ◽  
Radiological Studies

Idiopathic localised dilatation of the intestine (ILDI) presenting in adults is rare and difficult to diagnose. Only 18 cases have been reported in the literature. We report a case of a 32-year-old woman presenting with abdominal pain and intermittent small bowel obstruction. After detailed radiological studies, the patient, known for Crohn’s disease, was scheduled for laparoscopy in the suspicion of small bowel stricture. A localised dilatation of the ileum was found intraoperatively and subsequently resected. A systematic review of this rare pathology in adults is carried out. ILDI should be part of the differential diagnosis in patients with unexplained abdominal pain or gastrointestinal bleeding in the presence of segmental dilatation of the intestine. Surgical resection is the treatment of choice.

scholarly journals Motion-Cyclo-oxygenase-2 Selective Nonsteroidal Anti-Inflammatory Drugs are as Safe as Placebo for the Stomach: Arguments for the Motion

2003 ◽  
Vol 17 (5) ◽  
pp. 339-341 ◽  
Author(s):  
Richard H Hunt
Keyword(s):  
Small Bowel ◽  
Blood Loss ◽  
Previous History ◽  
High Dose ◽  
Duodenal Ulcers ◽  
Low Dose Aspirin ◽  
History Of ◽  
Important Addition ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Traditional nonsteroidal anti-inflammatory drugs (NSAIDs) are known to cause gastritis, gastric and duodenal ulcers, and gastrointestinal (GI) blood loss, as well as alterations in small bowel permeability. Patients at a high risk for these complications include those who are older than 60 years of age, those with a previous history of complicated peptic disease and bleeding, and those who take high dose or multiple NSAIDs, including low dose aspirin, corticosteroids or anticoagulants. The introduction of selective inhibitors of cyclo-oxygenase-2 (COX-2) has provided effective treatment of inflammatory arthritis and musculoskeletal pain, with dramatic reductions in the risk of GI adverse events. The two most widely prescribed coxibs are celecoxib and rofecoxib, and others are being developed. Endoscopic studies have revealed that coxibs are only half as likely to induce upper GI ulceration than are traditional NSAIDs, and are as safe as placebo. Furthermore, the newer drugs do not cause excessive blood loss from the GI tract and do not affect small bowel permeability. The Vioxx Gastrointestinal Outcomes Research Study (VIGOR) revealed that the incidence of myocardial infarction was significantly lower with naproxen than rofecoxib, although this study was not designed to look at this endpoint. Coxibs are an important addition to the pharmacotherapy of inflammatory disease.

Nonsteroidal Anti-Inflammatory Drug-Induced Small Bowel Stricture in Rheumatoid Arthritis

2019 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Taro Horino ◽  
Osamu Ichii ◽  
Tomohiro Eguchi ◽  
Satoshi Inotani ◽  
Tatsuki Matsumoto
Keyword(s):  
Rheumatoid Arthritis ◽  
Small Bowel ◽  
Drug Induced ◽  
Inflammatory Drug ◽  
Small Bowel Stricture ◽  
Anti Inflammatory ◽  
Bowel Stricture

scholarly journals Small bowel diaphragm disease from long-term non-steroidal anti-inflammatory use

2019 ◽  
Vol 12 (10) ◽  
pp. e230735
Author(s):  
Ryan Pereira ◽  
Kellee Slater
Keyword(s):  
Small Bowel ◽  
Laparoscopic Hysterectomy ◽  
Ageing Population ◽  
Abdominal Ct ◽  
Diaphragm Disease ◽  
History Of ◽  
General Surgeons ◽  
Inflammatory Drugs ◽  
Anti Inflammatory

Small bowel diaphragm disease (SBDD) is characterised by circumferential lesions of short length (<5 mm), causing intrinsic stenosis of the small bowel lumen. A 63-year-old women with a history of long-term non-steroidal anti-inflammatory use, presented with a 12-month history of intermittent episodes of colicky abdominal pain, nausea and vomiting. Her only past surgery was a laparoscopic hysterectomy. Abdominal CT demonstrated an area of thickening in the mid small bowel, however a diagnostic laparoscopy failed to demonstrate adhesions or any external abnormality. A capsule endoscope did not progress beyond the mid small bowel at the site of a suspected diaphragm. The patient underwent a laparotomy and using the retained capsule as a marker, the area of bowel affected by SBDD was identified. With an ageing population and the widespread use of non-steroidalanti-inflammatory drugs, general surgeons may see an increase in the incidence of SBDD.

scholarly journals Idiopathic small bowel diaphragm disease: a case report

2020 ◽  
Vol 2020 (10) ◽  
Author(s):  
Omar Marghich ◽  
Alexandre Maubert ◽  
Efoé-Ga Yawod Olivier Amouzou ◽  
Louis Denimal ◽  
Emmanuel Benizri ◽  
...  
Keyword(s):  
Case Report ◽  
Small Bowel ◽  
Rare Condition ◽  
Diaphragm Disease ◽  
History Of ◽  
Inflammatory Drugs ◽  
Nsaid Usage ◽  
Anti Inflammatory

Abstract Small bowel diaphragm disease is a rare condition usually associated with the prolonged use of non-steroidal anti-inflammatory drugs (NSAID) and that can be mistaken and treated as other pathologies. We describe a case of a 64-year-old man with a prolonged course of pain and subacute bowel obstructions, without any history of NSAID usage, found to have a multiple diaphragmatic stricture in the small bowel.

Lockdown dilemma: ingestion of magnetic beads presenting as right iliac fossa pain and subacute small bowel obstruction

2020 ◽  
Vol 13 (11) ◽  
pp. e236429
Author(s):  
Bankole Oyewole ◽  
Anu Sandhya ◽  
Ian Maheswaran ◽  
Timothy Campbell-Smith
Keyword(s):  
Abdominal Pain ◽  
Small Bowel ◽  
Magnetic Beads ◽  
Iliac Fossa ◽  
Serous Fluid ◽  
Magnetic Resonance Scan ◽  
History Of ◽  
Right Iliac Fossa Pain ◽  
Multiple Episodes ◽  
Safety Netting

A 13-year-old girl presented with a 3-day history of migratory right iliac fossa pain. Observations and inflammatory markers were normal, and an ultrasound scan was inconclusive. A provisional diagnosis of non-specific abdominal pain or early appendicitis was made, and she was discharged with safety netting advice. She presented again 6 days later with ongoing abdominal pain now associated with multiple episodes of vomiting; hence, the decision was made to proceed to diagnostic laparoscopy rather than a magnetic resonance scan for further assessment. Intraoperative findings revealed 200 mL of serous fluid in the pelvis, normal-looking appendix, dilated stomach and a tangle of small bowel loops. Blunt and careful dissection revealed fistulous tracts that magnetised the laparoscopic instruments. A minilaparotomy was performed with the extraction of 14 magnetic beads and the repair of nine enterotomies. This case highlights the importance of careful history taking in children presenting with acute abdominal pain of doubtful aetiology.

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