scholarly journals Benign Cardiac Neoplasms in the United States - a Thirteen-Year Review.

Cardiology ◽  
2021 ◽  
Author(s):  
Neiberg de Alcantara Lima ◽  
Kristina Byers-Spencer ◽  
Kamil Cwikla ◽  
Cuyler Huffman ◽  
Mireya Diaz ◽  
...  
Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Neiberg A Lima ◽  
Kamil Cwikla ◽  
Kristina Byers-Spencer ◽  
Cuyler Huffman ◽  
Mireya Diaz ◽  
...  

Introduction: Malignant cardiac neoplasms (MCN) are rare and deadly. Metastatic cardiac tumors are known to be more frequent than primary neoplasms of the heart. Due to the uncommon nature of this disease, there are few data-driven studies examining the incidence in the United States or analyzing rates and types of complications. The purpose of our study was to better describe the types, characteristics and trends of MCN in the United States. Methods: This study is a retrospective review of data from the HCUP-NIS Database from 2002-2014. Inclusion criteria consisted of the presence of indication for MCN. Additionally, we queried the database for MCN-associated comorbidities and procedures. SAS studio was utilized for analysis. Results: The data consists of 482,872,274 weighted hospital discharges, 5,610 of which had MCN. Fifty three percent were male. Eighty percent had a metastatic cardiac tumor and twenty percent had a primary neoplasm of the heart (Figure 01). Median cost of admission was 35,855 USD, three times higher than the national average. A total of 568 (10.12%) patients died during the admission. Stroke and arterial embolization were reported in 192 (3.42%) and 54 (0.96%) cases, respectively. Weight loss, fever and endocarditis were reported in 70 (1.24%), 162 (2.89%) and 53 (0.94%) patients, respectively. Pulmonary hypertension co-occurred in 225 (4.01%) patients. Atrial tachyarrhythmias, ventricular arrhythmias, syncope and cardiac arrest were reported in 1,119 (19.95%), 185 (3.30%), 39 (0.70%), and 88 (1.57%) cases. Sinus node dysfunction and severe AV nodal block co-occurred in 46 and 50 patients. Conclusions: Morbidity and mortality are high in patients with MCN. The majority of MCN are associated with metastatic disease, with especially lung, skin/bone/soft tissue and gastrointestinal being the commonest.


Author(s):  
A. Hakam ◽  
J.T. Gau ◽  
M.L. Grove ◽  
B.A. Evans ◽  
M. Shuman ◽  
...  

Prostate adenocarcinoma is the most common malignant tumor of men in the United States and is the third leading cause of death in men. Despite attempts at early detection, there will be 244,000 new cases and 44,000 deaths from the disease in the United States in 1995. Therapeutic progress against this disease is hindered by an incomplete understanding of prostate epithelial cell biology, the availability of human tissues for in vitro experimentation, slow dissemination of information between prostate cancer research teams and the increasing pressure to “ stretch” research dollars at the same time staff reductions are occurring.To meet these challenges, we have used the correlative microscopy (CM) and client/server (C/S) computing to increase productivity while decreasing costs. Critical elements of our program are as follows:1) Establishing the Western Pennsylvania Genitourinary (GU) Tissue Bank which includes >100 prostates from patients with prostate adenocarcinoma as well as >20 normal prostates from transplant organ donors.


Author(s):  
Vinod K. Berry ◽  
Xiao Zhang

In recent years it became apparent that we needed to improve productivity and efficiency in the Microscopy Laboratories in GE Plastics. It was realized that digital image acquisition, archiving, processing, analysis, and transmission over a network would be the best way to achieve this goal. Also, the capabilities of quantitative image analysis, image transmission etc. available with this approach would help us to increase our efficiency. Although the advantages of digital image acquisition, processing, archiving, etc. have been described and are being practiced in many SEM, laboratories, they have not been generally applied in microscopy laboratories (TEM, Optical, SEM and others) and impact on increased productivity has not been yet exploited as well.In order to attain our objective we have acquired a SEMICAPS imaging workstation for each of the GE Plastic sites in the United States. We have integrated the workstation with the microscopes and their peripherals as shown in Figure 1.


2001 ◽  
Vol 15 (01) ◽  
pp. 53-87 ◽  
Author(s):  
Andrew Rehfeld

Every ten years, the United States “constructs” itself politically. On a decennial basis, U.S. Congressional districts are quite literally drawn, physically constructing political representation in the House of Representatives on the basis of where one lives. Why does the United States do it this way? What justifies domicile as the sole criteria of constituency construction? These are the questions raised in this article. Contrary to many contemporary understandings of representation at the founding, I argue that there were no principled reasons for using domicile as the method of organizing for political representation. Even in 1787, the Congressional district was expected to be far too large to map onto existing communities of interest. Instead, territory should be understood as forming a habit of mind for the founders, even while it was necessary to achieve other democratic aims of representative government.


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