Occupational Safety in Chemosensitivity Tests: A Method to Minimize the Risk of Contamination While Maximizing the Safety for the Examiner

Chemotherapy ◽  
2021 ◽  
pp. 1-5
Author(s):  
Manfred Henrich ◽  
Svenja Hartung ◽  
Christiane Herden
Keyword(s):  
Cell Cultures ◽  
Occupational Safety ◽  
Health And Safety ◽  
Risk Minimization ◽  
Work Safety ◽  
Established Method ◽  
In Vitro Chemosensitivity ◽  
Chemosensitivity Assays ◽  
User Friendly

In vitro chemosensitivity tests are a widely used and established method in research. In laboratory environments, work safety is particularly important when working with carcinogenic, mutagenic, or reprotoxic (CMR) substances. When working with cell cultures, minimizing the risk of contamination with CMR substances and protecting the experimenter must be in the foreground of the experimental setup since risk minimization and occupational safety when handling CMR substances are mandatory. To minimize any personnel risk, studies with solid CMR substances should be carried out in a closed system. However, publications on occupational health and safety in laboratory environments in which CMR substances are tested in cell cultures are rare. Therefore, this article presents an easily applicable and safe method for improving work safety for in vitro chemosensitivity tests when working with CMR substances while also taking cell culture hygiene into account. For this purpose, a risk assessment of the test design was carried out, and the steps that were decisive for safety were highlighted. Some user-friendly and easily reproducible elements are presented, which increase the occupational safety of in vitro chemosensitivity assays, especially by reducing the risk of personnel contamination.

Counterpoint: Chemosensitivity Assays for Recurrent Ovarian Cancer

2011 ◽  
Vol 9 (1) ◽  
pp. 121-124 ◽  
Author(s):  
Maurie Markman
Keyword(s):  
Ovarian Cancer ◽  
Clinical Trials ◽  
Recurrent Ovarian Cancer ◽  
Evidence Based ◽  
Chemosensitivity Assay ◽  
Reliable Evidence ◽  
In Vitro Chemosensitivity ◽  
Frequent Use ◽  
Chemosensitivity Assays

Unfortunately, no reliable evidence-based data have shown any in vitro chemosensitivity assay strategy to be clinically useful in the management of recurrent ovarian cancer, despite frequent use. Several clinical trials have been proposed with the potential to support or refute the relevance of these approaches.

scholarly journals Legal review of the implementation of work safety and health atpt multi nabatimaleo unit, pohuwato district

2019 ◽  
Vol 3 (2) ◽  
pp. 163-167
Author(s):  
HERLINA SULAIMAN
Keyword(s):  
Personal Protective Equipment ◽  
Management System ◽  
Occupational Safety ◽  
Safety Management ◽  
Health And Safety ◽  
Occupational Safety And Health ◽  
Occupational Accidents ◽  
Protective Equipment ◽  
Work Safety ◽  
Safety And Health

Implementation of Occupational Safety and Health at PT. Multi Nabati Unit Maleo is done by Enviromental Unit, Health and Safety. EHS is a policy applied by PT Multi Nabati Unit Maleo in providing protection for the safety and health of its workers. EHS is a direct handle or the first handle if there is an accident and also work to make preventive efforts to prevent accidents. In addition, the company develops the health and work safety management system (SMK3 & L). The efforts undertaken by PT Multi Nabati To reduce the risk of occupational accidents by applying: Engineering (engineering), Administration (administration) and Labor must use APD (Personal protective equipment).

scholarly journals The Regulatory Standards and Work Safety: A Review of Literature and Research Directions

2019 ◽  
Vol 7 (5) ◽  
pp. 102-112
Author(s):  
Vilson Menegon Bristot ◽  
Gabriela Aline Borges ◽  
Leopoldo Pedro Guimarães Filho ◽  
Antônio Cleber Gonçalves Junior ◽  
Bruno Brogni Uggioni ◽  
...  
Keyword(s):  
Occupational Safety ◽  
Health And Safety ◽  
Scientific Production ◽  
Review Of Literature ◽  
Work Safety ◽  
Research Directions ◽  
Research Opportunities ◽  
Regulatory Standards

Since the first initiatives related to health and safety at work there has been a lot of progress in this area. However, there is still a lot to be improved, especially in Brazil, since the country is among the countries with the highest number of accidents at work and in academic terms, represents a low participation in the scientific production in the area. Thus, given the context, this article aims to review the literature on regulatory norms and occupational safety, identifying gaps and research opportunities related to the area. The results indicate an increase in the relevance of the theme, however the majority of the studies present a fragmented and punctual approach. Regulatory norms 15 and 32 were the most frequent, and the industrial and health sectors were the predominant ones.

scholarly journals Modern Trends in Occupational Safety Management

2019 ◽  
Vol 2 (2) ◽  
pp. 126-138
Author(s):  
Teresa Lis ◽  
Krzysztof Nowacki
Keyword(s):  
Occupational Health ◽  
Occupational Safety ◽  
Industrial Revolution ◽  
Safety Management ◽  
Health And Safety ◽  
Occupational Health And Safety ◽  
Management Systems ◽  
The European Union ◽  
Work Safety ◽  
Systems Requirements

Abstract Problems related to work safety have been accompanying humanity since the dawn of time. In times before the Industrial Revolution, human and animal muscle strength was used to work, and “safe work” solutions were developed and introduced individually by the user or supervising the work. Only a change in the way work was done due to the industrial revolution, the introduction of new energy sources, the transformation of manufactories into factories and the birth of the working class brought about greater, concrete changes. It was at that time that various machines and devices began to be introduced into the workplace, which on the one hand improved work and on the other hand created more and more potentially dangerous situations. Security was started holistically and institutionally. With the transformation and return of capitalism, the subject of real work safety returned. Health and safety was to be not only a fashionable slogan, but a value that was supposed to guarantee profit – in accordance with the principle that accidents reduce productivity. It was also connected with the process of adapting Polish law in the field of health and safety to the law of the European Union (EU), which resulted from Poland’s pursuit of EU membership. Moreover, an important factor initiating these changes was the interest of enterprises in quality management systems compliant with the ISO 9000 series and environmental management systems compliant with the ISO 14000 series, and related attempts to adapt the system management concept to the area of occupational health and safety, resulting in PN-N standards 18000 series. This publication analyzes the new standard PN-ISO 45001:2018 – “Occupational health and safety management systems – Requirements with guidance for use” comparing it with the standard PN-N 18001:2004 – “Occupational health and safety management. Requirements”.

scholarly journals Zaštita i sigurnost na radu u nastavnom programu medicinskih sestara/tehničara opće njege u Republici Hrvatskoj i susjednim zemljama

Sigurnost ◽  
2019 ◽  
Vol 61 (1) ◽  
pp. 39-44
Author(s):  
Kristina Horvat
Keyword(s):  
Professional Training ◽  
Occupational Safety ◽  
Health And Safety ◽  
Diagnostic Procedures ◽  
Occupational Safety And Health ◽  
Occupational Accidents ◽  
Economic Losses ◽  
Work Safety ◽  
Human Right ◽  
Safety And Health

Protection at work and work safety are the basic principles of the human right to work in a dignified way that guarantees protection of life and health at work. The scope of work of nurses/technicians includes diagnostic procedures, treatment and patient care. However, performance of these tasks can lead to health damage. Preventing and reducing injuries, occupational diseases, diseases related to the work as well as the preservation and improvement of health have a huge impact on reducing economic losses. Thus, a building of awareness is required so that the investment in occupational safety and health and safety at work will not be perceived as an unnecessary expense or a huge cost, but a long-term profitable investment. Additional costs and major expenses arise when the safety and health at work are not in proper focus. Employers and employees are the key factors, but the most important effort is to start raising awareness about the importance of protection and safety at work during the training for certain professions. Teachers play an important role in developing positive attitudes and understanding the importance of prevention of occupational accidents, occupational and related diseases. They greatly influence the maintenance of protection and safety from the earliest days to the end of service, including even the life expectancy of an individual person. If future young health care workers start with the acquisition of knowledge and skills of work safety at the beginning of their professional training, then safety and protection at work will become an integral part of the working process for them. They will develop a proper attitude toward the importance of occupational safety and health, which will guide them throughout their entire working life.

scholarly journals ANALISIS IKLIM KESELAMATAN KERJA DI PT. XYZ BALIKPAPAN 2021

2021 ◽  
Vol 5 (2) ◽  
pp. 1303-1309
Author(s):  
Deni Eri Zulfirman ◽  
ZULKIFLI DJUNAIDI
Keyword(s):  
Work Environment ◽  
Risk Taking ◽  
Occupational Safety ◽  
Safety Climate ◽  
Health And Safety ◽  
Work Safety ◽  
Average Value ◽  
True Value ◽  
Safety And Health ◽  
Safety Priority

This study was conducted to determine the safety climate, the safety climate reflects workers' perceptions of the true value of safety in an organization - as a contributing factor to the reduction of accidents due to accidents. The purpose of this study was to determine the level of health and safety scores in the company. This study uses a descriptive analytical method with a total of 100 respondents (total respondents) with a variable measuring the level of work safety using a questionnaire published by the National Research Center for the Danish work environment, namely the Nordic Climate Safety Questionnaire 50 (NOSACQ-50) which contains 50 statements and has been completed. tested and translated in 40 languages, one of which is Indonesian. This research was conducted at PT. XYZ Balikpapan which starts in January until March 2021,. The results of this study indicate that there are 3 dimensions that have an average value below 3.30, namely the management safety empowerment dimension, management safety justice dimension and worker’s safety priority and risk non-acceptance dimension. Suggested improvements include making decisions and receiving advice and input from workers regarding work safety and being fair to workers regarding occupational safety and health for management and prioritizing work safety and not taking risks even though the work is busy and reducing risk-taking behavior that is dangerous for workers.

scholarly journals PELAKSANAAN KESELAMATAN DAN KESEHATAN KERJA TERHADAP PEKERJA HARIAN LEPAS PADA PHENON EVENT DENPASAR

2020 ◽  
Vol 8 (11) ◽  
pp. 1816
Author(s):  
Geraldine Thirdaswari Adnyana ◽  
I Wayan Wiryawan
Keyword(s):  
Occupational Health ◽  
Research Method ◽  
Occupational Safety ◽  
Health And Safety ◽  
Legal Protection ◽  
Occupational Health And Safety ◽  
Office Work ◽  
Work Safety ◽  
Safety And Health ◽  
Health Standards

Penulisan jurnal ini bertujuan untuk mengetahui pelaksanaan keselamatan dan kesehatan kerja bagi pekerja harian lepas serta untuk mengetahui faktor-faktor yang menjadi hambatan dalam pelaksanaan perlindungan hukum atas kesehatan dan keselamatan kerja bagi pekerja harian lepas pada Perusahaan Phenon Event di Denpasar. Metode penelitian yang digunakan yakni metode penelitian hukum empiris, menggunakan pendekatan dari peraturan perundang-undangan (the statue approach) dan pendekatan fakta. Hasil penelitian menunjukkan bahwa Perusahaan Phenon Event Denpasar belum melaksanakan kesehatan dan keselamatan kerja sesuai dengan standar yang diatur dalam Peraturan Menteri Kesehatan No. 48 Tahun 2016 Tentang Standar Keselamatan dan Kesehatan Kerja Perkantoran. Adapun faktor-faktor yang menjadi hambatan dalam pelaksanaan perlindungan kesehatan dan keselamatan kerja pada Perusahaan Phenon Event Denpasar adalah ketidakmampuan perusahaan untuk memenuhi standar kesehatan dan keselamatan kerja sebagaimana diatur dalam Peraturan Menteri Kesehatan No. 48 Tahun 2016 Tentang Standar Keselamatan dan Kesehatan Kerja Perkantoran. This journal writing aims to determine the implementation of occupational safety and health for casual daily workers and to find out the factors that become obstacles in the implementation of legal protection for occupational health and safety for casual daily workers at the Phenon Event Company in Denpasar. The research method used is the empirical legal research method, using the approach of statutory regulations (the statue approach) and the fact approach. The results showed that the Phenon Event Denpasar Company had not implemented occupational health and safety in accordance with the standards stipulated in the Minister of Health Regulation No. 48 of 2016 concerning Office Work Safety and Health Standards. The factors that become obstacles in the implementation of occupational health and safety protection at the Phenon Event Denpasar Company are the company's inability to meet occupational health and safety standards as regulated in the Minister of Health Regulation No. 48 of 2016 concerning Office Work Safety and Health Standards.

scholarly journals Work safety climate. Comparison of selected occupational groups

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243056
Author(s):  
Marta Stasiła-Sieradzka ◽  
Agata Chudzicka-Czupała ◽  
Marta Znajmiecka-Sikora
Keyword(s):  
Occupational Safety ◽  
Safety Climate ◽  
Safety Management ◽  
Health And Safety ◽  
Working Environment ◽  
Management Policy ◽  
Work Safety ◽  
Occupational Groups ◽  
Significant Difference ◽  
The Individual

Implementation of effective programs to improve occupational safety should be linked to an understanding of the specific nature of the given job. The aim of the research was to compare occupational groups with different job-related specificities: industrial production line workers, retail workers and mine rescuers, in terms of their assessment of the work safety climate. The survey covered 2,995 respondents with diversified demographic characteristics. The study used an abridged version of the Safety Climate Questionnaire by Znajmiecka-Sikora (2019) to assess 10 separate safety climate dimensions. The results of the MANOVA multivariate analysis, Wilks’ multivariate F-tests and univariate F tests prove that there is a statistically significant difference between the respondents representing the three occupational groups collectively in terms of global assessment of all work safety climate dimensions, and also indicate significant differences between workers belonging to the three occupational groups in terms of their assessment of the individual dimensions of the work safety climate, except the organization’s occupational health and safety management policy as well as technical facilities and ergonomics, which may be due to the universality of the requirements set for organizations with regard to these two aspects of safe behavior. The differences observed in the assessment of the remaining work safety climate dimensions induces one to promote more differentiated and individualized activities, taking into account the work specificity and the nature of the threats occurring in the respective working environment of the representatives of the different occupations. The difference in assessment of the work safety climate found in the research encourages one to create practical programs for safety, not only in the procedural and technical dimension, but also in the social and psychological one.

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