Characteristics and Laboratory Findings of Food-Induced Anaphylaxis in Children: Study in an Asian Developing Country

2021 ◽  
pp. 1-9
Author(s):  
Rapisa Nantanee ◽  
Narissara Suratannon ◽  
Pantipa Chatchatee
Keyword(s):  
Developing Country ◽  
Immunoglobulin E ◽  
Tertiary Care ◽  
Elevated Serum ◽  
Cow’S Milk ◽  
Care Hospital ◽  
Serum Tryptase ◽  
Cutaneous Manifestations ◽  
Cow's Milk ◽  
Geographical Regions

<b><i>Introduction:</i></b> Food allergy is the major cause of pediatric anaphylaxis. Characteristics and triggers may be different in different geographical regions. Studies focusing on food-induced anaphylaxis (FIA) in Asian developing countries are limited. Our study aimed to study characteristics of FIA in a tertiary care center in an Asian developing country. <b><i>Methods:</i></b> Retrospective review of pediatric anaphylaxis admission and outpatient visit at a tertiary care hospital in Bangkok, Thailand during 2008–2018 was performed. Data regarding clinical presentation, place reaction occurred, time of onset, investigations (serum tryptase, specific immunoglobulin E, and skin test), treatment, and follow-up periods were collected. <b><i>Results:</i></b> One hundred seventy-four anaphylaxis admission records of which 61 episodes of FIA were retrieved. Data from outpatients visit consisted of 17 patients. Most patients were male (76.7%). The median age was 7.1 years (interquartile range 1.9–12.4). The major causes of FIA were shrimp/shellfish (37%), wheat (15.1%), and cow’s milk (11%). Food causing anaphylaxis varied according to age-group: infants had anaphylactic reactions to egg, wheat, and cow’s milk, preschools to wheat and peanut, and older children to shrimp/shellfish. Cutaneous manifestations occurred in all patients, followed by lower respiratory tract symptoms (83.6%) and gastrointestinal symptoms (50.8%). There was no biphasic anaphylaxis reported. Elevated serum tryptase was found in only 4 patients (7%). <b><i>Conclusion:</i></b> Recognizing characteristics of pediatric FIA is crucial. The common causes of FIA in our study in Asian children were egg in infants, wheat and peanut in preschool children, and shrimp/shellfish in school-age children and adolescents. Skin manifestation presented in all patients with FIA.

scholarly journals Functional constipation in Bangladeshi children: experience of demography and probable risk factors from a tertiary care hospital

2020 ◽  
Vol 7 (7) ◽  
pp. 1619
Author(s):  
Md. Wahiduzzaman Mazumder ◽  
Maimuna Sayeed ◽  
Md. Benzamin ◽  
Mahfuza Chowdhury
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Tertiary Care ◽  
Functional Constipation ◽  
Cow’S Milk ◽  
Care Hospital ◽  
Age Group ◽  
Cow's Milk ◽  
Academic Activity ◽  
Potential Risk Factors

Background: Constipation is a common problem throughout childhood. It is important to be fully aware of the factors involved in developing constipation in children. There are few published articles on childhood constipation in Bangladesh. In this study, our aim was to evaluate demography and probable/potential risk factors for functional constipation in Bangladeshi children.Methods: The study was carried out among 179 children from May 2018 to June 2019 in the department of Pediatric Gastroenterology and Nutrition, Bangabandhu Sheikh Mujib Medical University (BSMMU) both indoor and outdoor basis. Children with constipation who fulfilled the ROME III criteria were evaluated for demography and probable/potential risk factors of constipation.Results: A total of 179 subjects were included in the final analysis. Among them, 54.75% were boys and 45.25% were girls. Constipation was found more in the age group above 5 years (56.42%), then in 2 to 5 years age group (33.52%) and lower in below 2 years of age (10.6%). Constipation was more among children living in urban area (55.3%) than in rural area (44.69%). Constipation was the presenting complaint in 76.54% subjects, other complaints were abdominal pain (47.49%), anorexia (24.02%), vomiting (19.56%). Diet low in fiber (72.63%) was found as the most common potential risk factor, other factors were ingestion of cow’s milk (32.96%), not having regular meals with parents (19.55%), consumption of junk foods (28.49%). Staying with grandparents (16.76%), living in hostel or madrasa / residential religious institute (5.03%), long period of academic activity, [homework (10.61%) / tutor and coaching (7.26%)], unhygienic toilet in school (6.14%) were also found to be probable associated factors in this study.Conclusions: Functional constipation was found more in boy’s and above five year age group. Low dietary fiber, consumption of cow’s milk and junk food, unwillingness to use toilets in school, long time in academic activity, were found to be potential underlying risk factors of constipation.

scholarly journals 24-h intraesophageal pH determination in children allergic to cow's milk protein at a tertiary care hospital

2014 ◽  
Vol 79 (1) ◽  
pp. 3-6
Author(s):  
J.A. Ramírez-Mayans ◽  
E.M. Toro-Monjaraz ◽  
J. Romero-Trujillo ◽  
R. Cervantes-Bustamante ◽  
F. Zárate-Mondragón ◽  
...  
Keyword(s):  
Milk Protein ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Cow’S Milk ◽  
Care Hospital ◽  
Cow's Milk ◽  
Cow’S Milk Protein

scholarly journals Functional Constipation in Children: Demography and risk factors analysis from a Tertiary Care Hospital of Bangladesh

2021 ◽  
Vol 44 (3) ◽  
pp. 148-152
Author(s):  
Md Wahiduzzaman Mazumder ◽  
Shariful Hasan ◽  
Kaniz Fathema ◽  
Md Rukunuzzaman ◽  
ASM Bazlul Karim
Keyword(s):  
Risk Factors ◽  
Potential Risk ◽  
Urban Areas ◽  
Tertiary Care ◽  
Functional Constipation ◽  
Cow’S Milk ◽  
Care Hospital ◽  
Cross Sectional ◽  
Cow's Milk ◽  
Potential Risk Factors

Background: Constipation is not uncommon in childhood. This study was aimed to evaluate demography and probable/potential risk factors for functional constipation in Bangladeshi children. Materials & Method: This cross-sectional study was carried out among 179 children from May 2018 to June 2019 in the department of Pediatric Gastroenterology and Nutrition, BSMMU, Dhaka both indoor and outdoor basis. Collected data from children with constipation who fulfilled the Rome III criteria were analyzed by SPSS 20. Results: Among 179 children, 54.75% were boys, and 45.25% girls. It was found more in age group above 5 years (56.42%), then in 2 to 5 years (33.52%) and lower in below 2 years (10.6%). Constipation was more in urban areas (55.3%) than in rural (44.69%). Among potential risk factors, low fiber in diet (72.63%) was most common, other factors were ingestion of cow’s milk (32.96%), not having regular meals with parents (19.55%), consumption of junk foods (28.49%), Staying with grandparents (16.76%), living in hostel or madrasa / residential, religious institute (5.03%), long period of academic activity (7.26%), unhygienic toilet in school (6.14%) were also found to be probable risk factors in this study. Conclusion: Functional constipation was found more in boys & above five-year age groups. Low dietary fiber, consumption of cow’s milk & junk food, unwillingness to use toilets in school were found as potential underlying risk factors of constipation. Bangladesh J Child Health 2020; VOL 44 (3) :148-152

Differential Cytokine Expression in the Duodenum and Rectum of Children with Non-Immunoglobulin E-Mediated Cow’s Milk Protein Allergy

2021 ◽  
Author(s):  
Erick M. Toro-Monjaraz ◽  
Gabriela Fonseca-Camarillo ◽  
Flora Zárate-Mondragón ◽  
Ericka Montijo-Barrios ◽  
José Cadena-León ◽  
...  
Keyword(s):  
Milk Protein ◽  
Immunoglobulin E ◽  
Cytokine Expression ◽  
Cow’S Milk ◽  
Cow's Milk ◽  
Cow’S Milk Protein

scholarly journals Pattern of dermatologic manifestations in polycystic ovarian disease cases from a tertiary care hospital

2018 ◽  
Vol 5 (1) ◽  
pp. 197 ◽  
Author(s):  
Preeti Jain ◽  
Shailendra Jain ◽  
Abhishek Singh ◽  
Shewtank Goel
Keyword(s):  
Lifestyle Modification ◽  
Tertiary Care ◽  
Care Hospital ◽  
Cardiovascular Risks ◽  
Polycystic Ovarian Disease ◽  
Cutaneous Manifestations ◽  
Ovarian Disease ◽  
General Physical Examination ◽  
Female Pattern Hair Loss ◽  
Dermatologic Manifestations

Background: Dermatologists often play a significant role in its management. Cutaneous features of hyperandrogenism in Polycystic ovarian syndrome (PCOS) have varied presentation. Aim of this study was the pattern of dermatologic manifestations in polycystic ovarian disease in northern Indian females.Methods: Patients registering for treatment of polycystic ovarian disease at Dermatology outpatients department during April 2016 to March 2017 formed the study population. Residents interviewed the study subjects at the OPD. General physical examination, systemic examination, breast and pelvic examination, along with detailed dermatological examination were conducting after taking the history. Hormonal analysis was performed after an overnight fasting using enzyme immunoassay.Results: FSH and LH levels were 5.05±1.86 IU/L and 8.14±5.21 IU/L respectively. Testosterone levels were found to be 61.01±25.32 ng/dl. DHEAS levels among them were 130.05±41.21μg/dl. Two commonest cutaneous manifestations were hirsutism and acne seen in 83.8% and 59.5% of subjects. Female pattern hair loss was seen in 45.6% females. Three most frequent hormonal abnormalities noted in our study subjects were raised L/H ratio, testosterone and LH levels seen in approximately 45%, 35% and 21% cases.Conclusions: The cutaneous manifestations of PCOS reserve a major role in its management by dermatologists. A lifestyle modification along with systemic treatment remains mainstay of treatment. Monitoring for the foreseen cardiovascular risks should start early to downgrade the morbidity.

scholarly journals Gestational Age Specific Postnatal Growth Curves for Singleton Babies in Tertiary Hospital of Western Nepal

2017 ◽  
Vol 56 (207) ◽  
pp. 325-330
Author(s):  
Santosh Pathak ◽  
Nagendra Chaudhary ◽  
Prativa Dhakal ◽  
Shyam Kumar Mahato ◽  
Sandeep Shrestha ◽  
...  
Keyword(s):  
Birth Weight ◽  
Gestational Age ◽  
Economic Status ◽  
Tertiary Care ◽  
Growth Curves ◽  
Tertiary Hospital ◽  
Care Hospital ◽  
Cross Sectional ◽  
Intrauterine Growth ◽  
Geographical Regions

Introduction: Measurement of birth weight (BW), crown heel length (CHL), head circumference (HC) and chest circumference used to assess the intrauterine growth of a baby vary with altitude, race, gender, socio economic status, maternal size, and maternal diseases. The study aimed to construct centile charts for BW, CHL and HC for new born at different gestational ages in western Nepal. Methods:  This was a descriptive cross sectional study done over a period of 15 months in a tertiary care hospital of western Nepal. BW, length, HC and CC were measured within 12-24 hours of birth. Gestational age was estimated from first day of last menstrual period, maternal ultrasonology and New Ballard’s scoring system. Microsoft 2007 Excel and SPSS-16 was used for data analysis. Cole’s Lambda Mu Sigma method was used for constructing centile curves. Results: Out of 2000 babies analysed, 1910 samples were used to construct smoothed intrauterine growth curve of BW, CHL, and HC from 33-42 weeks of gestation. 57.35% (1147) were male, mean gestational age was 38.13 ±2.44 weeks, where 21.5% were preterm and 1.7% post term. The means of BW, CHL, HC and CC were 2744.78 gm, 47.80 cm, 33.18 cm, and 30.20 cm with standard deviations of 528.29, 3.124, 1.78, and 2.35 respectively. These data vary as compared to the Kathmandu data, in case of birth weight for 10th and 90th centiles, and at 90th centile in case of length. Conclusions: This necessitates the update in the existing growth charts and develop in different geographical regions of a country.

Increasing cancer incidence in a tertiary care hospital in a developing country, India

2015 ◽  
Vol 52 (1) ◽  
pp. 133 ◽  
Author(s):  
T Cherian ◽  
P Mahadevan ◽  
S Chandramathi ◽  
J Govindan ◽  
IL Mathew
Keyword(s):  
Developing Country ◽  
Cancer Incidence ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Care Hospital
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