Analysis of Voiding Impairment after Prostate Biopsy and the Effect of Doxazosin Treatment: Outcomes from a Regional Cancer Center

2021 ◽  
pp. 1-6
Author(s):  
Yi Zheng ◽  
Fuding Bai ◽  
Nan Zhang ◽  
Huifeng Wu
Keyword(s):  
Prostate Biopsy ◽  
Transrectal Ultrasound ◽  
Urine Volume ◽  
Cancer Center ◽  
Control Group ◽  
Urinary Flow ◽  
Voiding Difficulty ◽  
Male Patients ◽  
Baseline Values

<b><i>Introduction:</i></b> The aim of this study was to investigate the association of transrectal ultrasound (TRUS)-guided prostate biopsy with voiding impairment and the efficacy of doxazosin treatment. <b><i>Methods:</i></b> A prospective observational study including 200 male patients undergoing TRUS-guided prostate biopsy was performed between May 2020 and December 2020. One hundred patients underwent biopsy with doxazosin (doxazosin group). The remaining 100 patients underwent biopsy without doxazosin (control group). All patients were questioned regarding post-biopsy voiding difficulty and acute urinary retention. The International Prostate Symptom Score (IPSS), maximal urinary flow rate (Q<sub>max</sub>), and residual urine volume were recorded before biopsy and at 7 and 30 days after biopsy. <b><i>Results:</i></b> There were no significant differences in baseline parameters between the two groups. The rate of post-biopsy voiding difficulty in the doxazosin group was significantly lower than that in the control group. Compared with baseline values, doxazosin treatment significantly improved IPSS, quality of life scores, and Q<sub>max</sub> after biopsy (<i>p</i> &#x3c; 0.05). The baseline values of IPSS and prostate size may be risk factors for post-biopsy voiding difficulty. <b><i>Conclusion:</i></b> TRUS-guided prostate biopsy causes transient voiding impairments, which may be improved by doxazosin treatment.

Effect of alpha-blocker use on morbidity and lower urinary tract symptoms in patients undergoing transrectal ultrasound-guided prostate biopsy

2021 ◽  
pp. 039156032110383
Author(s):  
Remzi Salar ◽  
Güven Erbay
Keyword(s):  
Prostate Biopsy ◽  
Voiding Dysfunction ◽  
Prostate Volume ◽  
Transrectal Ultrasound ◽  
Urine Volume ◽  
Maximum Flow ◽  
Control Group ◽  
Alpha Blocker ◽  
Urinary Tract Symptoms ◽  
Significant Difference

Objective: To evaluate voiding dysfunction and morbidity after transrectal ultrasound (TRUS)-guided prostate biopsy and to investigate whether pre-intervention alpha-blocker treatment had any effect on morbidity and voiding dysfunction. Material and methods: The study included 197 consecutive patients who underwent TRUS-guided prostate biopsy between January 2014 and January 2018. The patients were divided into two groups, those receiving alpha-blocker (silodosin) and those not receiving alpha-blocker treatment before the procedure (controls). All patients were evaluated before and one week after the procedure with the International Prostate Symptom Score (IPSS), measurements of maximum flow rate ( Qmax), post-void residual urine volume (PVR) and prostate volume, and procedure-related complications were also recorded. All analyzed parameters were compared by within-group and between-group evaluations. Results: There was no significant difference between the two groups in terms of IPSS, Qmax and prostate volume values before biopsy. In the follow-up evaluation performed on the seventh day after biopsy, IPSS, PVR and prostate volume were found to be increased, whereas Qmax was decreased in the control group ( p < 0.05). In the silodosin group, an increase in prostate volume was observed, but there were no significant changes in IPSS, Qmax and PVR values. Acute urinary retention (AUR) after the biopsy procedure developed in two patients (2%) in the silodosin group, and in nine patients (9.1%) in the control group ( p = 0.02). No significant difference was found between the two groups in terms of biopsy-related complications, except for AUR. Conclusion: We believe that alpha-blocker treatment initiated before biopsy may be advantageous in preventing voiding dysfunction that may develop after the procedure.

scholarly journals Lidocaine spray administration in transrectal ultrasound-guided prostate biopsy: Five years of experience

2014 ◽  
Vol 86 (4) ◽  
pp. 340 ◽  
Author(s):  
Lucio Dell’Atti
Keyword(s):  
Pain Score ◽  
Prostate Biopsy ◽  
Low Cost ◽  
Prostate Gland ◽  
Transrectal Ultrasound ◽  
Pain Scale ◽  
Patient Comfort ◽  
Ultrasound Guided ◽  
Male Patients ◽  
Lidocaine Spray

Objectives: We report in this singlecenter study our results of a five-year experience in the administration of lidocaine spray (LS) during ultrasound-guided prostate biopsy (TPB). Material and Methods: Between August 2008 and July 2013 a total of 1022 consecutive male patients scheduled for TPB with elevate PSA (≥ 4 ng/ml) and (or) abnormal digital rectal and (or) suspect TRUS were considered eligible for the study. Each patient was treated under local anaesthesia with LS (10 gr/100 ml), applied two minutes before the procedure. TPB was performed with the patient in the left lateral decubitus using multi-frequency convex probe “end-fire”. Two experienced urologists performed a 14-core biopsy, as first intention. After the procedure each patient was given a verbal numeric pain scale (VNS). The evaluation was differentiated in two scales VNS: VNS 1 for the insertion of the probe and the manoeuvres associated, while VNS 2 only for the pain during needle’s insertion. Results: Pain scores were not statistically significant different with regard to the values of PSA and prostate gland volume. Pain score levels during probe insertion and biopsy were significantly different: the mean pain score according to VNS was 3.3 (2-8) in the first questionnaire (VNS1) (p &lt; 0.001) and 2.1 (1-7) in the second one (VNS2) (p &lt; 0.125). The 8.2% of cases referred severe or unbearable pain (score ≥ 7), 74% of patients referred no pain at all. Only 21 patients would not ever repeat the biopsy or would request a different type of anaesthesia, while 82% of them would repeat it in the same way. In only eight patients we have not been able to insert TRUS probe. Conclusions: Our pain score data suggest that LS provides efficient patient comfort during TPB reducing pain both during insertion of the probe and the needle. This non-infiltrative anaesthesia is safe, easy to administer, psychologically well accepted by patients and of low cost.

Plasmakinetic Vapor Enucleation of the Prostate with Button Electrode versus Plasmakinetic Resection of the Prostate for Benign Prostatic Enlargement >90 ml: Perioperative and 3-Month Follow-Up Results of a Prospective, Randomized Clinical Trial

2015 ◽  
Vol 95 (3) ◽  
pp. 260-264 ◽  
Author(s):  
Keqin Zhang ◽  
Dingqi Sun ◽  
Hui Zhang ◽  
Qingwei Cao ◽  
Qiang Fu
Keyword(s):  
Urine Volume ◽  
Operation Time ◽  
Urinary Flow ◽  
Benign Prostatic Enlargement ◽  
Effective Technique ◽  
Prostatic Enlargement ◽  
Postvoid Residual Urine ◽  
Maximum Urinary Flow

Objective: To evaluate plasmakinetic vapor enucleation of the prostate (PVEP) with button electrode and plasmakinetic resection of the prostate (PKRP) in patients with urinary symptoms due to benign prostatic enlargement (BPE) >90 ml. Methods: A total of 112 patients with symptomatic BPE were randomly assigned to either PKRP or PVEP prospectively from August 2012 to May 2014 in our department. Perioperative and postoperative data were investigated during a 3-month follow-up. Results: PVEP was significantly superior to PKRP in terms of operation time (63.9 ± 7.7 vs. 78.1 ± 13.6 min, p < 0.001), hemoglobin loss (1.18 ± 0.30 vs. 1.63 ± 0.38 g/dl, p < 0.001), serum sodium decrease (2.9 ± 0.7 vs. 4.3 ± 0.8 mmol/l, p < 0.001), catheterization duration (49.3 ± 12.2 vs. 78.1 ± 14.8 h, p < 0.001) and hospital stay (100.2 ± 28.3 vs. 116.0 ± 29.2 h, p = 0.004). There were no statistical differences in blood transfusion between the two groups. In addition, there were no statistical differences in maximum urinary flow rate, International Prostate Symptom Score, postvoid residual urine volume, quality-of-life score, transient incontinence, and urethral stricture at 3 months postoperatively. Conclusions: PVEP with button electrode is an equally effective technique for treatment of large BPE with PKRP, with more safety and faster recovery. It may become the superior alternative to PKRP for patients with large BPE.

INFORMATIVE VALUE OF COMPUTER STABILOMETRY IN THE DIAGNOSIS OF VIBRATION DISEASE FROM THE EFFECTS OF GENERAL VIBRATION

2021 ◽  
Author(s):  
E.E. Konnikova ◽  
◽  
A.G. Popova ◽  
N.I. Slugrov ◽  
Keyword(s):  
Work Experience ◽  
Control Group ◽  
Vibration Disease ◽  
Equilibrium Function ◽  
Study Results ◽  
Average Work ◽  
Male Patients ◽  
Romberg Test ◽  
Medical Examinations

Abstract: A statistical analysis of stabilometric study results of 50 male patients with vibration disease (VD) from the effects of general vibration (GV) (average work experience 26,7±6,2) has been carried out. The control group (CG) included 50 men who have not been exposed to the general vibration. The compared groups were comparable by age: the average age of patients with vibration disease was 56.34+5.15, patients of the control group-58.22+-7.05. The study of the support symmetry and equilibrium function was carried out using the Romberg test on the St-150 stabiloplatform (Biomera, Moscow) in a vertical stand with European installation of feet in the positions of open (OE) and closed eyes (CE). A comparative analysis of the parameters of support symmetry in patients with VD from GV revealed a statistically significant sagittal asymmetry in the phases of OE and CE than in individuals of CG. Among the balancing parameters, the most informative parameters of computer stabilometry in patients with VD from GV were: an increase in the area of the statokinesiogram, a decrease in energy efficiency in both phases of the study, and an increase in the speed of the statokinesiogram in phase with CE. Computer stabilometry can be recommended as an additional objective research method in the diagnosis of early stages of VD from GV to improve the quality of periodic medical examinations.

scholarly journals A multicentre single-blind randomized controlled trial comparing bipolar and monopolar transurethral resection of the prostate

2013 ◽  
Vol 5 (6) ◽  
pp. 385
Author(s):  
Carlos E. Méndez-Probst ◽  
Linda Nott ◽  
Stephen E. Pautler ◽  
Hassan Razvi
Keyword(s):  
Quality Of Life ◽  
Transurethral Resection ◽  
Controlled Trial ◽  
Transrectal Ultrasound ◽  
Life Assessment ◽  
Urinary Flow ◽  
Tissue Specimens ◽  
Single Blind ◽  
Length Of Hospitalization

Introduction: Monopolar transurethral resection of the prostate(TURP) is the gold standard surgical therapy for men with lower urinarytract symptoms due to benign prostatic hyperplasia. Althoughgenerally considered safer, TURP experience is limited in Canada.Methods: Forty-three patients from 5 Canadian centres were randomizedto TURP with either bipolar or monopolar platforms.Patients underwent baseline determinations of American UrologicalAssociation (AUA) symptom score, peak urinary flow rate, postvoidresidual bladder volume and transrectal ultrasound prostatevolume. Primary outcome measures were improvement in AUAsymptom score, quality of life assessment and bother assessment.Secondary outcomes included procedural times, duration of catheterization,length of hospitalization, complications and the degreeof thermal artifact in tissue specimens. Patients were followed for6 months.Results: Twenty-two patients were treated with bipolar and 21 withmonopolar TURP. Preoperative demographics were not statisticallydifferent between groups. Postoperative data collection times wereequivalent in AUA symptom, quality of life, bother and sexualfunction assessments. No differences were observed in the proceduretime (60.7 min, bipolar vs. 47.4, monopolar) or the durationof urethral catheterization (1.5 days, bipolar vs. 1.1, monopolar).More patients in the bipolar group were discharged on the sameday of surgery. There were no differences in the degree of tissuethermal artifact or complication rate.Conclusion: This trial suggests equivalent short-term outcomes formen undergoing monopolar or bipolar TURP.

scholarly journals Effective Concentration of Lidocaine Plus Fentanyl for Caudal Block in Patients Undergoing Transrectal Ultrasound Guided Prostate Biopsy

2016 ◽  
Vol 2016 ◽  
pp. 1-4
Author(s):  
Jinguo Wang ◽  
Honglan Zhou ◽  
Wei An ◽  
Na Wang ◽  
Yang Gao
Keyword(s):  
Side Effects ◽  
Prostate Biopsy ◽  
Pain Perception ◽  
Transrectal Ultrasound ◽  
Effective Concentration ◽  
Mixed Solution ◽  
Caudal Block ◽  
Ultrasound Guided ◽  
Step Size ◽  
Male Patients

Objective. This study determined the effective concentration (EC) of lidocaine plus 75 μg fentanyl for caudal block in patients undergoing transrectal ultrasound (TRUS) guided prostate biopsy. Methods. Consecutive male patients scheduled for TRUS guided prostate biopsy were enrolled. The mixed solution for caudal block contained lidocaine and 75 μg fentanyl, in total 20 mL. The concentration of lidocaine was determined using the up-and-down method, starting at 0.8% (a step size of 0.1%). A successful caudal block was defined by no pain perception during biopsy. The EC50 of lidocaine for successful caudal block was calculated and side effects were evaluated. Results. A total of 23 patients were recruited. The EC50 of lidocaine for successful caudal block was 0.53%. Conclusions. Lidocaine of 0.53% combined with 75 μg fentanyl resulted in excellent caudal block in 50% of male patients undergoing transrectal ultrasound guided prostate biopsy.

scholarly journals Addition of Ceftriaxone and Amikacin to a Ciprofloxacin plus Metronidazole Regimen for Preventing Infectious Complications of Transrectal Ultrasound-Guided Prostate Biopsy: A Randomized Controlled Trial

2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Mohammad-Hossein Izadpanahi ◽  
Kia Nouri-Mahdavi ◽  
Seyed Mahmood Majidi ◽  
Mohammad-Hatef Khorrami ◽  
Farshid Alizadeh ◽  
...  
Keyword(s):  
Prostate Biopsy ◽  
Controlled Trial ◽  
Intervention Group ◽  
Transrectal Ultrasound ◽  
Infectious Complications ◽  
Control Group ◽  
Ultrasound Guided ◽  
Prophylactic Regimen ◽  
Randomized Controlled ◽  
Group 1

Background. The objective of this study was to evaluate the efficacy of adding single doses of ceftriaxone and amikacin to a ciprofloxacin plus metronidazole regimen on the reduction of infectious complications following transrectal ultrasound-guided prostate biopsy (TRUS Bx). Materials and Methods. Four hundred and fifty patients who were candidates for TRUS Bx were divided into two groups of 225 each. The control group received ciprofloxacin 500 mg orally every 12 hours together with metronidazole 500 mg orally every 8 hours from the day prior to the procedure until the fifth postoperative day. In the second group, single doses of ceftriaxone 1 g by intravenous infusion and amikacin 5 mg/kg intramuscularly were administered 30–60 minutes before TRUS Bx in addition to the oral antimicrobials described for group 1. The incidence of infection was compared between the groups. Results. The incidence of infectious complications in the intervention group was significantly lower than that in the control group (4.6% versus 0.9%, p=0.017). Conclusion. The addition of single doses of intramuscular amikacin and intravenously infused ceftriaxone to our prophylactic regimen of ciprofloxacin plus metronidazole resulted in a statistically significant reduction of infectious complications following TRUS Bx.

scholarly journals Diode laser vaporization of prostate as treatment for benign prostatic enlargement: Initial results of 73 patients with 1 year follow-up

2014 ◽  
Vol 61 (1) ◽  
pp. 21-24
Author(s):  
Miodrag Acimovic ◽  
Dragutin Rafailovic ◽  
Uros Bumbasirevic ◽  
Uros Babic ◽  
Veljko Santric ◽  
...  
Keyword(s):  
Diode Laser ◽  
Intraoperative Complications ◽  
Urine Volume ◽  
Laser Vaporization ◽  
Urinary Flow ◽  
Benign Prostatic Enlargement ◽  
Prostatic Enlargement ◽  
Initial Results

Objective: Our objective is to evaluate the efficacy, safety and 12 month outcome of a 980 nm diode laser with Twister fiber in the treatment of benign prostatic enlargement. Materials and methods: Between February 2011 and January 2013, 73 patients with benign prostatic enlargement had undergone diode laser vaporization of prostate at our institution. The following parameters were assessed at baseline, and after a follow-up period of 3 and 12 months: International Prostate Symptom Score, peak urinary flow rate, post-void residual urine volume, and quality of life score. Results: The procedure was completed successfully in all patients with no intraoperative complications. At 12 months postoperatively the percentage improvements in IPSS was-69.09%, Qmax +197%, PVR-88.54%, and QoL-68.29%. Conclusion: Diode laser vaporization of prostate is safe and effective method for treatment of benign prostatic enlargement.

scholarly journals A RANDOMIZED CONTROLLED TRIAL FOR THE EFFECTS OF SEXUAL BEHAVIOUR GUIDANCE ON SEXUAL FUNCTION AMONG YOUNG AND MIDDLE-AGED MALE PATIENTS WITH RECTAL CANCER AFTER MILES OPERATION

2019 ◽  
Vol 15 (2) ◽  
pp. e20-e26
Author(s):  
Li-Ying Zhang ◽  
Hui-Juan Bian ◽  
Ya-Fei Kuang ◽  
Guo-Li Cao ◽  
Tao-Hsin Tung
Keyword(s):  
Rectal Cancer ◽  
Sexual Behavior ◽  
Sexual Function ◽  
Sexual Life ◽  
Control Group ◽  
Middle Aged ◽  
Male Patients ◽  
Experimental Group ◽  
Middle Aged Male

Purpose This study was conducted to explore the effect of intervention in the form of sexual behavior guidance on the quality of sexual life of young and middle-aged male patients with rectal cancer. Methods Twenty cases of young and middle-aged male patients with rectal cancer were randomly divided into experimental and control group in each group including 10 cases per group. The control group was given the traditional health education after the rectal cancer Miles operation. While the experimental group was given sexual behavior guidance and “sex focused training therapy” after the Miles operation and before sexual intercourse in order to overcome erectile dysfunction. The International Index of Erectile Function (IIEF-5) questionnaire was used to measure the sexual functionality of both groups upon admission, at the time of discharge and after 3, 6 and 9 months. Results In the experimental group, patients with normal sexual function at the 6th and 9th month after discharge were 7 cases and 9 cases respectively, which were significantly higher than the control group which included 5 cases and 6 cases (p-value < 0.05). Conclusion In conclusion, sexual health education not only could effectively improve the sexual function of young and middle-aged male patients with rectal cancer after Miles operation, but also could improve the quality of the sexual life of the patients. It is considered to be worthy to promotion and application on clinical practice.

Sign in / Sign up

Export Citation Format

Share Document