scholarly journals Determinants of the Glomerular Maximal Size Threshold

2021 ◽  
pp. 1-3
Author(s):  
Nobuo Tsuboi
Keyword(s):  
2005 ◽  
Vol 173 (4S) ◽  
pp. 265-265 ◽  
Author(s):  
Robert L. Grubb ◽  
Nicol S. Corbin ◽  
Peter Choyke ◽  
Gladys M. Glenn ◽  
Kathleen Hurley ◽  
...  

2012 ◽  
Vol 56 (6) ◽  
pp. 1826-1827
Author(s):  
Charles J. Keith ◽  
Marc A. Passman ◽  
Michael J. Gaffud ◽  
Zdenek Novak ◽  
Marjan U. Mujib ◽  
...  

1979 ◽  
Vol 26 (2) ◽  
pp. 197-200 ◽  
Author(s):  
Béla Bollobás ◽  
Pierre Duchet
Keyword(s):  

1986 ◽  
Vol 43 (6) ◽  
pp. 1242-1248 ◽  
Author(s):  
Ransom A. Myers ◽  
Jeffrey A. Hutchings ◽  
R. John Gibson

The covariation of growth and maturation in male Atlantic salmon parr, Salmo salar, produces a relationship characterized by a size threshold below which individuals generally do not mature. The threshold of 70–72 mm fork length is evident both within and among populations. Parr maturation can reduce growth during the second year of life by an average of 4.0%. Among-year variation in growth rate affects the yearly incidence of maturation for males at age 1 + but has no detectable effect on the total proportion of male parr maturing in a population. Increases in the proportion of mature parr in the Matamek River, Quebec, can be explained by variation in growth alone; there is no evidence for genetic changes in this population.


2021 ◽  
Author(s):  
Yiran Chang ◽  
Danie J Dickinson

Regulation of subcellular components' localization and motion is a critical theme in cell biology. Cells use the actomyosin cortex to regulate protein distribution on the plasma membrane, but the interplay between membrane binding, cortical movements and protein distribution remains poorly understood. In a polarizing one-cell stage Caenorhabditis elegans embryo, actomyosin flows transport PAR protein complexes into an anterior cortical domain to establish the anterior-posterior axis of the animal. Oligomerization of a key scaffold protein, PAR-3, is required for aPAR cortical localization and segregation. Although PAR-3 oligomerization is essential for polarization, it remains unclear how oligomer size contributes to aPAR segregation because PAR-3 oligomers are a heterogeneous population of many different sizes. To address this question, we engineered PAR-3 to defined sizes. We report that PAR-3 trimers are necessary and sufficient for PAR-3 function during polarization and later embryo development, while larger PAR-3 clusters are dispensable. Quantitative analysis of PAR-3 diffusion showed that PAR-3 clusters larger than a trimer are transported by viscous forces without being physically captured by the actomyosin cortex. Our study provides a quantitative model for size-dependent protein transportation of membrane proteins by cortical flow.


2001 ◽  
Vol 30 (1) ◽  
pp. 34-58
Author(s):  
Laura J. Downing

A body of work in Prosodic Morphology clearly establishes the importance of prosodic constituents like the foot as templates conditioning morpheme size. A striking finding of this research is that morphological footing is independent of metrical footing in many languages, as the footing required for particular morphological processes is often not identical to that required for phonological processes like stress assignment. However, recent OT research on Prosodic Morphology has made the opposite claim. Within this theory, the Generalized Template Hypothesis (GTH) proposes that no morpheme-particular templates defining minimal and maximal size are necessary. Instead, templates are always derivable from general principles of the grammar, like independently motivated metrical footing. This paper presents evidence from Ndebele showing that the GTH is too strong. In Ndebele, several different verb forms are subject to a minimality condition. In some cases, the minimality condition can be derived through independent metrical footing, as the GTH predicts. However, in several cases it cannot, showing that morpheme-particular size constraints are still a necessary part of the grammar.


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