Outcomes following Craniosynostosis Surgery at a Tertiary Care Center in the Middle East

2021 ◽  
pp. 1-9
Author(s):  
Omar Najjar ◽  
Naji AbouChebel ◽  
Carine Zeeni ◽  
Marwan W. Najjar
Keyword(s):  
Middle East ◽  
Clinical Features ◽  
Care Center ◽  
Tertiary Care ◽  
Surgical Approaches ◽  
Tertiary Care Center ◽  
Postoperative Blood Transfusion ◽  
Estimated Blood Loss ◽  
Traumatic Fracture ◽  
Cosmetic Outcomes

<b><i>Background:</i></b> Despite advancements in craniosynostosis surgery, open surgical approaches remain crucial for the management of infants &#x3e;6 months of age and in those with complex synostosis. The clinical features of craniosynostosis remain poorly characterized in the Middle East. This study sought to assess the clinical features and outcomes of infants undergoing craniosynostosis surgery at a tertiary care center in Lebanon. <b><i>Methods:</i></b> A retrospective review was performed of all patients who underwent craniosynostosis surgery from December 2006 to December 2018 at the American University of Beirut Medical Center, Lebanon. Clinicodemographic characteristics, complications, and recurrence outcomes were recorded and evaluated using descriptive statistics. <b><i>Results:</i></b> Thirty-five infants met the inclusion criteria, with a mean age of 9.0 ± 4.0 months. The most common site of suture involvement was metopic (28.6%), followed by unilateral coronal (25.7%), sagittal (20.0%), bicoronal (8.6%), and multiple sites (17.1%). Five patients (14.3%) had syndromic synostosis. Median estimated blood loss was 200 mL, and median volume of transfused packed red blood cells was 180 mL. Two patients (5.7%) experienced postoperative complications, including postoperative blood transfusion (<i>n</i> = 1)and wire protrusion requiring removal (<i>n</i> = 1). Three patients (8.6%) required reoperation: 2 (5.7%) for resynostosis and 1 for traumatic fracture repair. Caregivers of all patients reported high satisfaction with cosmetic outcomes 4 weeks postoperatively. <b><i>Conclusions:</i></b> With appropriate perioperative precautions, open craniosynostosis surgery can be performed with minimal complications, low recurrence rates, and satisfactory cosmetic outcomes. Additional population-level data are needed to better characterize craniosynostosis patterns and outcomes in the Middle East.

scholarly journals High rates of advanced prostate cancer in the Middle East: Analysis from a tertiary care center

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Deborah Mukherji ◽  
Marilyne Daher ◽  
Talar Telvizian ◽  
Christelle Dagher ◽  
Zahi Abdul-Sater ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Middle East ◽  
Advanced Prostate Cancer ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

Cardiac risk factors and events in patients with prostate cancer commencing androgen deprivation therapy: Analysis from a tertiary care center in the Middle East.

2021 ◽  
Vol 39 (6_suppl) ◽  
pp. 73-73
Author(s):  
Mona Hassan ◽  
Talar Telvizian ◽  
Mostafa Abohelwa ◽  
Hadi Skouri ◽  
Deborah Mukherji
Keyword(s):  
Prostate Cancer ◽  
Risk Factors ◽  
Cardiovascular Risk ◽  
Middle East ◽  
Cardiovascular Events ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Cardiac Events ◽  
Artery Disease

73 Background: Androgen deprivation therapy (ADT) is the mainstay of treatment for advanced prostate cancer, improving symptoms and prolonging survival. There is an association between ADT use and cardiovascular events, particularly in men with pre-existing risk factors. There are no definite guidelines to stratify patients based on cardiovascular risk prior to ADT initiation. This is the first study on cardiac risks and events in patients on ADT from Lebanon and the Middle East region, a population known to have a high prevalence of cardiovascular risk factors. Methods: A retrospective chart review of 236 patients with prostate cancer who received ADT therapy at a tertiary care center in Lebanon was performed. 167 had a full set of data and were included in analysis. Cardiovascular risk factors at baseline and cardiovascular events on ADT were reviewed. Results: The median age of our cohort was 68, range 48-92 years. The majority of patients had stage 4 diseases at diagnosis (49.8%) with a median duration of 12 months on ADT. In our cohort 24.4% had body mass index > 30, 52.1% had smoking history, 27.4% were diabetic, 28.8 % had history of coronary artery disease, 10.6% had heart failure history and 54.6% had hypertension. Less than half of the patients had a documented lipid profile at baseline. Twenty two patients (9.5%) had documented cardiac events following ADT initiation. Conclusions: In this cohort of patients from the Middle East we found that one third of the population had established coronary artery disease at baseline and 9.5% had documented cardiac events on ADT initiation. Our study highlights the gaps in cardiovascular risk assessment for this high risk group of patients with prostate cancer. Risk and resource-stratified algorithms are needed before starting ADT therapy for optimal cardiovascular health. Increased awareness, collaboration and referral mechanisms between oncologists, urologist and cardiologists are also needed.

scholarly journals Dengue fever. Clinical features of 567 consecutive patients admitted to a tertiary care center in Saudi Arabia

2017 ◽  
Vol 38 (10) ◽  
pp. 1025-1033 ◽  
Author(s):  
Samar Badreddine ◽  
Fahmi Al-Dhaheri ◽  
Ammar Al-Dabbagh ◽  
Abdulrahman Al-Amoudi ◽  
Maged Al-Ammari ◽  
...  
Keyword(s):  
Saudi Arabia ◽  
Dengue Fever ◽  
Clinical Features ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center

scholarly journals Uterine rupture revisited: Predisposing factors, clinical features, management and outcomes from a tertiary care center in Turkey

2013 ◽  
Vol 29 (3) ◽  
Author(s):  
Abdulkadir Turgut ◽  
Ali Ozler ◽  
Mehmet Siddik Evsen ◽  
Hatice Ender Soydinc ◽  
Neval Yaman Goruk ◽  
...  
Keyword(s):  
Clinical Features ◽  
Uterine Rupture ◽  
Care Center ◽  
Tertiary Care ◽  
Predisposing Factors ◽  
Tertiary Care Center

scholarly journals Acquired cold urticaria: Clinical features, particular phenotypes, and disease course in a tertiary care center cohort

2016 ◽  
Vol 75 (5) ◽  
pp. 918-924.e2 ◽  
Author(s):  
Gustavo Deza ◽  
Ana Brasileiro ◽  
Marta Bertolín-Colilla ◽  
Laia Curto-Barredo ◽  
Ramon M. Pujol ◽  
...  
Keyword(s):  
Clinical Features ◽  
Care Center ◽  
Tertiary Care ◽  
Disease Course ◽  
Tertiary Care Center ◽  
Cold Urticaria

scholarly journals Pyogenic liver abscess: Clinical features and microbiological profiles in tertiary care center

2020 ◽  
Vol 9 (8) ◽  
pp. 4337
Author(s):  
Naz Perween ◽  
ShyamK Kumar ◽  
BalramJ Omar ◽  
Ashish Kothari ◽  
AkashT Satsangi ◽  
...  
Keyword(s):  
Clinical Features ◽  
Liver Abscess ◽  
Care Center ◽  
Tertiary Care ◽  
Pyogenic Liver Abscess ◽  
Tertiary Care Center

scholarly journals Anaphylaxis in Omani Patients: A Study from a Tertiary Care Center

2021 ◽  
Author(s):  
Salem Al Tamemi ◽  
Yusra Al Lamki ◽  
Shafiq Ur-Rehman Naseem ◽  
Nabila Al Siyabi ◽  
Bushra Al Siyabi ◽  
...  
Keyword(s):  
Clinical Features ◽  
Allergic Disease ◽  
Clinical Symptoms ◽  
Care Center ◽  
Tertiary Care ◽  
University Hospital ◽  
Tertiary Care Center ◽  
Total Ige ◽  
Sultan Qaboos University ◽  
True Incidence

Objective: Anaphylaxis is an acute and potentially fatal allergic reaction. To the best of the author’s knowledge, no studies have yet been conducted to evaluate the spectrum of anaphylactic reactions among Omani patients. As such, this study aimed to describe the clinical features, causes, investigation, and management of anaphylaxis among patients presenting to a tertiary care center in Oman. Methods: This retrospective study took place between August 2005 and June 2020 at the allergy and immunology clinic of the Sultan Qaboos University Hospital, Muscat, Oman. All patients diagnosed with anaphylaxis during the study period were included. Data were collected from electronic medical records. Results: A total of 100 patients were diagnosed with anaphylaxis during the study period. Of these, 52% were male. The mean age was 15.9  16.2 years, with 70% being <18 years old. The eosinophil count ranged from 0–16.9 ×109 /L, with a mean of 0.8  2.2 ×109 /L and a median 2 of 0.30 (IQR: 0.15-0.65) ×109 /L. Total IgE levels ranged from 25–8,706 kIU/L, with a mean of 935.1  1369.5 kIU/L and a median of 500.4 (IQR: 186.0-972.5) kIU/L. Overall, the majority of patients had a family history of allergies (72%), other concomitant allergic condition (66%) and were all prescribed epinephrine (100%). The most common cause of anaphylaxis was food (65%), the second most frequent trigger was insect venom (32%). The majority of patients had one category cause (81%) however two or more causes were present in 19% of the patients. Clinical symptoms manifested most frequently as cutaneous (92%), and respiratory (85%). The majority of patients (87%) demonstrated involvement of more than one bodily system. Total IgE levels were significantly higher in patients with concomitant presence of other allergic conditions 1193.8 kIU/L compared to patients without another concomitant allergic disease mean 503.6 kIU/L (p=0.03). In addition, concomitant other allergic disease is significantly higher in patients <18 years of age 75.4% compared to patients >18 years of age 45.2% (p= 0.01). Conclusions: Due to its life-threatening nature, knowledge of the epidemiology and clinical features of anaphylaxis in different populations is necessary in order to deliver rapid treatment. This study found that the clinical features of anaphylactic patients in Oman were similar to those reported elsewhere. Further research is needed to determine the true incidence of anaphylaxis in Oman in order to minimize associated morbidity and mortality.

Demographics and outcomes of meningioma patients treated at a tertiary care center in the Middle East

2020 ◽  
Vol 195 ◽  
pp. 105846
Author(s):  
Hazem I. Assi ◽  
Lara Hilal ◽  
Ibrahim Abu-Gheida ◽  
Juliett Berro ◽  
Fares Sukhon ◽  
...  
Keyword(s):  
Middle East ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center
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