Dermatomyositis: Double trouble – Case Report

2021 ◽  
pp. 1-2
Author(s):  
Panagiota Xanthouli
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Clinical Presentation ◽  
The United States ◽  
Hispanic Population ◽  
Amyopathic Dermatomyositis ◽  
Comfort Care ◽  
Extensive Evaluation ◽  
Prognostic Implications ◽  
Japanese Descent

Background: Each myositis-specific autoantibody (MSA) tends to have a distinct clinical presentation. Coexistence of MSAs do not commonly occur. If they do, it is unknown if there is an overlap of clinical features or prognostic implications. There are a few reported cases of overlap between these antibodies, mostly reported in patients with Japanese descent. Our aim for this case report is to turn more attention and interest for future MSA profile studies in the Hispanic population, which may hopefully spur better therapies if we realize the prognostic implications of certain myositis subsets including double-positive autoantibody syndromes. Case presentation: A 27-year-old Hispanic female was admitted to the medical intensive care unit due to acute hypoxemic respiratory failure secondary to acute respiratory distress syndrome (ARDS). She had failed conventional mechanical ventilation and was cannulated for venovenous extracorporeal membrane oxygenation (VV-ECMO) to manage her respiratory failure. She had erythematous scaly plaques on bilateral 3rd metacarpophalangeal joints on examination. Her autoimmune workup revealed positivity for both anti-PL-7(threonyl) and anti-melanoma differentiation-associated gene 5 (MDA5) autoantibodies. After extensive evaluation, it was concluded that she had rapidly progressive interstitial lung disease (RPILD) due to amyopathic dermatomyositis. Despite maximal medical management, she was ultimately transitioned to comfort care measures and expired. Conclusion: We would like to highlight the rarity of double antibody positive amyopathic dermatomyositis. This unique clinical presentation has only been reported in persons of Japanese descent. Our case is likely to be the first reported to occur in a person of Hispanic descent in the United States. The rarity of our case could stimulate further study of overlapping MSA to understand its varied presentations and prognoses including possible tendency toward a rapidly progressive ILD phenotype. Earlier detection of these clinical syndromes can lead to better outcomes for patients with RPILD. This case report could also herald an increased recognition and understanding of MSA profile in the Hispanic population in the USA.

Dermatomyositis: Double trouble – Case Report

2021 ◽  
Vol 3 (1) ◽  
pp. 19-20
Author(s):  
Panagiota Xanthouli
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Clinical Presentation ◽  
The United States ◽  
Hispanic Population ◽  
Amyopathic Dermatomyositis ◽  
Comfort Care ◽  
Extensive Evaluation ◽  
Prognostic Implications ◽  
Japanese Descent

<b>Background:</b> Each myositis-specific autoantibody (MSA) tends to have a distinct clinical presentation. Coexistence of MSAs do not commonly occur. If they do, it is unknown if there is an overlap of clinical features or prognostic implications. There are a few reported cases of overlap between these antibodies, mostly reported in patients with Japanese descent. Our aim for this case report is to turn more attention and interest for future MSA profile studies in the Hispanic population, which may hopefully spur better therapies if we realize the prognostic implications of certain myositis subsets including double-positive autoantibody syndromes. <b>Case presentation:</b> A 27-year-old Hispanic female was admitted to the medical intensive care unit due to acute hypoxemic respiratory failure secondary to acute respiratory distress syndrome (ARDS). She had failed conventional mechanical ventilation and was cannulated for venovenous extracorporeal membrane oxygenation (VV-ECMO) to manage her respiratory failure. She had erythematous scaly plaques on bilateral 3rd metacarpophalangeal joints on examination. Her autoimmune workup revealed positivity for both anti-PL-7(threonyl) and anti-melanoma differentiation-associated gene 5 (MDA5) autoantibodies. After extensive evaluation, it was concluded that she had rapidly progressive interstitial lung disease (RPILD) due to amyopathic dermatomyositis. Despite maximal medical management, she was ultimately transitioned to comfort care measures and expired. <b>Conclusion:</b> We would like to highlight the rarity of double antibody positive amyopathic dermatomyositis. This unique clinical presentation has only been reported in persons of Japanese descent. Our case is likely to be the first reported to occur in a person of Hispanic descent in the United States. The rarity of our case could stimulate further study of overlapping MSA to understand its varied presentations and prognoses including possible tendency toward a rapidly progressive ILD phenotype. Earlier detection of these clinical syndromes can lead to better outcomes for patients with RPILD. This case report could also herald an increased recognition and understanding of MSA profile in the Hispanic population in the USA.

scholarly journals Vaping-associated lung injury: a case report and literature review

2021 ◽  
Vol 5 (2) ◽  
pp. 1-4
Author(s):  
Dewansh Goel ◽  
Kenneth Iyamu
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Lung Injury ◽  
Clinical Presentation ◽  
Clinical Course ◽  
Electronic Cigarettes ◽  
Invasive Mechanical Ventilation ◽  
Young Male ◽  
Acute Onset ◽  
Current Evidence

Usage of vaping and electronic cigarettes products is a growing trend among young adults, with rising rates worldwide. Such products are gaining popularity for many reasons including an alternative to smoking cigarettes, trying something new, or as a means to relax. While users may feel that these products are less harmful or a safer substitute to smoking traditional products, the side effect profile of vape inhalation has the potential for profound injury to the lung tissue and significant respiratory failure. We would like to present a case in which a young male who was evaluated at our Emergency department for acute onset respiratory failure subsequently requiring invasive mechanical ventilation in the setting of vaping associated lung injury (VALI). In the case report, we will highlight the patient’s clinical course as well as a summary of the current evidence surrounding evaluation, diagnosis and management of this emerging pathology. We want to emphasize the importance of a detailed history which should include the use of vaping products when a young patient presents with acute respiratory failure, allowing VALI to be in the differential diagnosis. Additionally, we want to compare the clinical presentation of VALI to that of COVID-19 pneumonia as they both have many similar attributes including symptoms and findings on lung imaging studies.

scholarly journals Clinically Amyopathic Dermatomyositis Caused by a Tattoo

2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Bing Han ◽  
Qiang Guo
Keyword(s):  
Immune Response ◽  
Case Report ◽  
Interstitial Lung Disease ◽  
Laboratory Test ◽  
Clinical Presentation ◽  
Unknown Origin ◽  
Skin Lesions ◽  
Amyopathic Dermatomyositis ◽  
Clinically Amyopathic Dermatomyositis ◽  
Left Chest

Introduction. Clinically amyopathic dermatomyositis (CADM) is a rare disease with unknown origin. It is characterized by the specific skin lesions of dermatomyositis (DM) without clinical or laboratory evidence of myopathy. Previous studies indicated that tattoo may induce immune response. Case Report. A 22-year-old male who tattooed butterfly on the left chest with blue and red ink. Then, he gradually had typical Gottron rash and interstitial lung disease (ILD) without weakness of the muscle. The clinical presentation and laboratory test represent the diagnosis of CADM. According to the history, CADM was induced by the tattoo five months before admission. Discussion. We first reported the CADM induced by a tattoo. However, further studies are still needed to approach the specific substances within the tattoo that trigger immune response.

Hemothorax as a Complication after Anterior Cervical Discectomy: Case Report

Neurosurgery ◽  
2005 ◽  
Vol 56 (4) ◽  
pp. E871-E871 ◽  
Author(s):  
B Sanjay Harhangi ◽  
Tomas Menovsky ◽  
Hans A.L. Wurzer
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Cervical Spine ◽  
Respiratory Failure ◽  
Surgical Procedures ◽  
English Language ◽  
Clinical Presentation ◽  
Anterior Cervical Discectomy ◽  
Cervical Discectomy ◽  
Language Literature

Abstract OBJECTIVE AND IMPORTANCE: Anterior cervical discectomy is one of the most frequently performed surgical procedures of the cervical spine. CLINICAL PRESENTATION: We describe a patient with a postoperative hemothorax as a complication after an anterior cervical discectomy. INTERVENTION: The patient was intubated, and reoperation and bronchoscopy were performed. CONCLUSION: To the best of our knowledge, such a complication has not been described before in the English-language literature. We conclude that hemothorax is a rare, although serious, complication after anterior cervical discectomy and should be included in the differential diagnosis for patients with respiratory failure after an anterior cervical discectomy.

scholarly journals CONGENITAL CARDITIS IN A NEWBORN (case report)

2019 ◽  
Vol 6 (1) ◽  
pp. 24-31
Author(s):  
M.O. Gonchar ◽  
A.V. Senatorova ◽  
N.K. Matsievskaya ◽  
D.V. Zatoloka
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Infectious Diseases ◽  
Diagnostic Criteria ◽  
Clinical Presentation ◽  
Clinical Manifestations ◽  
Intrauterine Infection ◽  
High Technology ◽  
Technology Research ◽  
Atypical Clinical Presentation

CONGENITAL CARDITIS IN A NEWBORN (case report)Gonchar M.O., Senatorova A.V., Matsiyevskaya N.K., Zatoloka D.V.Diagnosis of carditis in newborns presents a number of difficulties, even with the results of high-technology research methods. Carditis is characterized by the absence of specific diagnostic criteria, similarity of clinical manifestations of cardiovascular and respiratory failure in young children, including secondary to generalized infectious diseases. The article presents a case of an atypical clinical presentation of carditis in a child with a confirmed intrauterine infection.Key words: newborns, carditis, intrauterine infection ВРОДЖЕНИЙ КАРДИТ У НОВОНАРОДЖЕНОГО (клінічне спостереження)Гончар М.О., Сенаторова А.В., Мацієвська Н.К., Затолока Д.В.Встановлення діагнозу кардит у новонароджених має ряд труднощів, навіть при наявності результатів високотехнологічних методів дослідження. Кардит характеризується відсутністю специфічних діагностичних критеріїв, схожістю клінічних проявів серцево-судинної і дихальної недостатності у дітей раннього віку, в тому числі на тлі генералізованої інфекційної патології. У статті представлений випадок нетипового клінічного перебігу розвитку кардиту у дитини з підтвердженою внутрішньоутробною інфекцією.Ключові слова: новонароджені, кардит, внутрішньоутробна інфекція ВРОЖДЕННЫЙ КАРДИТ У НОВОРОЖДЕННОГО (клиническое наблюдение)Гончарь М.О., Сенаторова А.В., Мациевская Н.К., Затолока Д.В.Установление диагноза кардит у новорождённых имеет ряд сложностей, даже при наличие  результатов высокотехнологических методов исследования. Кардит характеризуется отсутствием специфических диагностических критериев, сходством клинических проявлений сердечно-сосудистой и дыхательной недостаточности у детей раннего возраста, в том числе на фоне генерализованной инфекционной патологии. В статье представлен случай нетипичного клинического течения развития кардита у ребенка с подтвержденной внутриутробной инфекцией.Ключевые слова: новорожденные, кардит, внутриутробная инфекция  

Cost-Effectiveness of Inhaled Nitric Oxide in the Treatment of Neonatal Respiratory Failure in the United States

PEDIATRICS ◽  
2003 ◽  
Vol 112 (6) ◽  
pp. 1351-1360 ◽  
Author(s):  
D. C. Angus ◽  
G. Clermont ◽  
R. S. Watson ◽  
W. T. Linde-Zwirble ◽  
R. H. Clark ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
United States ◽  
Cost Effectiveness ◽  
Respiratory Failure ◽  
The United States ◽  
Inhaled Nitric Oxide

Case Report: Hemoptysis localization – hearing with your eyes

POCUS Journal ◽  
2016 ◽  
Vol 1 (2) ◽  
pp. 7
Author(s):  
Barry Chan, MD
Keyword(s):  
Case Report ◽  
Respiratory Failure ◽  
Hemodynamic Instability ◽  
Clinical Vignette ◽  
Massive Hemoptysis ◽  
Airway Patency ◽  
Peripheral Site ◽  
Adventitious Sound

Clinical Vignette: 45 year old was transferred from a peripheral facility for acute massive hemoptysis though maintained sufficient airway patency with no evidence of hemodynamic instability or respiratory failure. Thoracic auscultation revealed vesicular breathing with no adventitious sound. CXR from the peripheral site was normal.

Bi-microbial Healthcare-Associate Endocarditis caused by Enterococcus faecalis and Burkholderia cepacia: A Case Report and literature review

2020 ◽  
Vol 02 ◽  
Author(s):  
Masood Ghori ◽  
Nadya O. Al Matrooshi ◽  
Samir Al Jabbari ◽  
Ahmed Bafadel ◽  
Gopal Bhatnagar
Keyword(s):  
Case Report ◽  
Infective Endocarditis ◽  
Literature Review ◽  
Enterococcus Faecalis ◽  
Surgical Management ◽  
Burkholderia Cepacia ◽  
Clinical Presentation ◽  
Complicated Course ◽  
Healthcare Associated ◽  
Echocardiographic Findings

: Infective Endocarditis (IE), a known complication of hemodialysis (HD), has recently been categorized as Healthcare-Associated Infective Endocarditis (HAIE). Single pathogen bacteremia is common, polymicrobial endocardial infection is rare in this cohort of the patients. We report a case of endocarditis caused by Enterococcus faecalis (E. faecalis) and Burkholderia cepacia (B. cepacia), a first ever reported combination of a usual and an unusual organism, respectively, in a patient on HD. Clinical presentation of the patient, its complicated course ,medical and surgical management ,along with microbial and echocardiographic findings is presented herein. The authors believe that presentation of this case of HAIE may benefit and contribute positively to cardiac science owing to the rare encounter of this organism as a pathogen in infective endocarditis and the difficulties in treating it.

Surgical management of choke through oesophagotomy in a buffalo: A case report

2017 ◽  
Vol 12 (3) ◽  
Author(s):  
Devasee Borakhatariya ◽  
A. B. Gadara
Keyword(s):  
Case Report ◽  
Surgical Management ◽  
Clinical Presentation ◽  
Clinical Signs ◽  
Thoracic Inlet ◽  
Cervical Oesophagus ◽  
Foreign Objects ◽  
History Of ◽  
Oesophageal Obstruction ◽  
Large Animals

Oesophageal disorders are relatively uncommon in large animals. Oesophageal obstruction is the most frequently encountered clinical presentation in bovine and it may be intraluminal or extra luminal (Haven, 1990). Intraluminal obstruction or “choke” is the most common abnormality that usually occurs when foreign objects, large feedstuff, medicated boluses, trichobezoars, or oesophageal granuloma lodge in the lumen of the oesophagus. Oesophageal obstructions in bovine commonly occur at the pharynx, the cranial aspect of the cervical oesophagus, the thoracic inlet, or the base of the heart (Choudhary et al., 2010). Diagnosis of such problem depends on the history of eating particular foodstuff and clinical signs as bloat, tenesmus, retching, and salivation

scholarly journals Complications of drowning: A case report

2019 ◽  
Vol 59 (5) ◽  
pp. 284-8
Author(s):  
Felicia Anita Wijaya ◽  
I Gde Doddy Kurnia Indrawan
Keyword(s):  
United States ◽  
Case Report ◽  
Brain Damage ◽  
The United States ◽  
Accidental Death ◽  
Common Cause ◽  
Death By Drowning

Unintentional drowning is the sixth most common cause of accidental death, accounting for 4,086 deaths (1.4 per 100,000) in the United States in 2007.1 In children, drowning is the second leading cause of injury-related death, and those aged 1–3 years have the highest rate of drowning.2 More than 1,400 pediatric drownings were reported in the United States in 2008.3 Many drowning deaths are due to lack of supervision in the bathtub, unprotected access to a pool, or lack of swimming skills.3 For every death by drowning, six children are hospitalized for drowning, and up to 10% of survivors experience severe brain damage.2

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