scholarly journals Colitis due to Cytomegalovirus and Herpes Simplex Type 2 as a Complication of a First Presentation of Inflammatory Bowel Disease

2021 ◽  
Vol 29 (1) ◽  
pp. 56-60
Author(s):  
Tiago Leal ◽  
Bruno Arroja ◽  
Dalila Costa ◽  
Carla Ferreira ◽  
João Bruno Soares ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Herpes Simplex ◽  
Opportunistic Infections ◽  
Antiviral Treatment ◽  
Herpes Simplex Type ◽  
Case Presentation ◽  
Systemic Corticosteroids ◽  
Inflammatory Bowel ◽  
High Degree

<b><i>Introduction:</i></b> The first presentation of ulcerative colitis may be an acute flare in about 15% of patients, requiring hospital admission. In acute severe steroid-refractory ulcerative colitis, cytomegalovirus (CMV) should be sought because it is a frequent cause of refractory disease. Herpes simplex colitis constitutes a rarer event in ulcerative colitis patients and it is usually associated with immunosuppression. <b><i>Case Presentation:</i></b> We report a case of a first presentation of ulcerative colitis complicated by CMV and herpes simplex type 2 coinfection. After a long period of systemic corticosteroids, the diagnosis of both CMV and herpes colitis was made. Despite antiviral treatment, colectomy was required due to a contained perforation. <b><i>Discussion/Conclusion:</i></b> This report highlights the importance of a high degree of suspicion for opportunistic infections in steroid/immunomodulator refractory ulcerative colitis, even in the first flare.

scholarly journals Acute recurrent lymphocytic meningitis in an immunocompetent HIV-positive African woman: Is it a Mollaret’s meningitis or not?

2017 ◽  
Vol 5 ◽  
pp. 2050313X1772264
Author(s):  
Katie Tharshana Yoganathan ◽  
Soumeya Cherif ◽  
Mariam Rashid ◽  
Kathir Yoganathan
Keyword(s):  
Cerebrospinal Fluid ◽  
Herpes Simplex ◽  
Opportunistic Infections ◽  
Herpes Simplex Type ◽  
African Woman ◽  
Hiv Positive ◽  
Neck Stiffness ◽  
Cell Counts ◽  
Lymphocytic Meningitis

We report a case of acute recurrent meningitis in an HIV-positive immunocompetent woman. In this case, a 34-year-old African woman with a known HIV infection presented with symptoms of acute meningitis. She was on combination antiretroviral therapy with abacavir, lamivudine, and nevirapine. Her HIV RNA level was <70 IU/mL, and CD4 counts were 640 cells/mm3. This indicates that she was not immunocompromised. She was febrile on examination, with marked neck stiffness. Her cerebrospinal fluid revealed raised white cell counts with 100% lymphocytes and mildly raised protein. Polymerase chain reaction confirmed herpes simplex type 2 meningitis. She recovered fully with aciclovir 800 mg three times a day. However, she was readmitted with a similar presentation 5 months after the initial admission. Her cerebrospinal fluid confirmed recurrent herpes simplex type 2 meningitis. This case alerts the profession to the possibility of non-opportunistic infections in an immunocompetent HIV-positive patient and of herpes simplex virus type 2 causing recurrent lymphocytic meningitis.

Sa1032 The Effect of Herpes Simplex Type-2 (Hsv-2) Suppression on Hepatitis C (HCV) Viral Load in Veterans With Hsv-2/HCV Co-Infection

2013 ◽  
Vol 144 (5) ◽  
pp. S-977 ◽  
Author(s):  
Mary Jane Burton ◽  
Alan D. Penman ◽  
Imran Sunesara ◽  
Casey A. Young ◽  
Brendan M. McGuire ◽  
...  
Keyword(s):  
Viral Load ◽  
Hepatitis C ◽  
Herpes Simplex ◽  
Herpes Simplex Type

Polyneuropathy After Herpes Simplex Type 2 Meningitis

1984 ◽  
Vol 77 (11) ◽  
pp. 1476 ◽  
Author(s):  
DONALD G. SEIBERT ◽  
J ELLIS SEALS
Keyword(s):  
Herpes Simplex ◽  
Herpes Simplex Type

Central diabetes insipidus: a complication of herpes simplex type 2 encephalitis in a patient with aids

1991 ◽  
Vol 90 (5) ◽  
pp. 658-659 ◽  
Author(s):  
Zuhayr T. Madhoun ◽  
Dwight B. DuBois ◽  
Jonathan Rosenthal ◽  
Joann C. Findlay ◽  
David C. Aron
Keyword(s):  
Herpes Simplex ◽  
Diabetes Insipidus ◽  
Central Diabetes Insipidus ◽  
Herpes Simplex Type
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