scholarly journals Severe Generalized Bullous Fixed Drug Eruption Treated with Cyclosporine: A Case Report and Literature Review

2021 ◽  
pp. 154-163
Author(s):  
Hailey C. Barootes ◽  
Erin R. Peebles ◽  
Doreen Matsui ◽  
Michael Rieder ◽  
Awatif Abuzgaia ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Cyclosporine A ◽  
Drug Eruption ◽  
Paediatric Population ◽  
Fixed Drug Eruption ◽  
Drug Eruptions ◽  
Fixed Drug ◽  
Paediatric Case ◽  
Oral Ibuprofen

Generalized bullous fixed drug eruptions (GBFDEs) are rare in the paediatric population. We present the case of a 7-year-old girl with GBFDE believed to be secondary to oral ibuprofen, who experienced rapid resolution of lesions and cessation of blistering with a 3-week course of oral cyclosporine. To the best of our knowledge, this is the first report of a paediatric case of GBFDE treated with cyclosporine. In our report, we review published cases of GBFDE in children, and all adult cases managed with cyclosporine.

scholarly journals Ofloxacin/ tinidazole induced fixed drug eruption- a case report

2021 ◽  
Vol 2 (1) ◽  
pp. 36-38
Author(s):  
Monika Kapoor
Keyword(s):  
Adverse Drug Reaction ◽  
Case Report ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Drug Induced ◽  
Drug Eruptions ◽  
Fixed Drug ◽  
Causative Agents ◽  
Inflammatory Drugs ◽  
Cutaneous Adverse Drug Reaction

Introduction: An immunological cutaneous adverse drug reaction is distinguished as sharply defined lesions with red rashes and sharp borders, erythematous lesions with or without blisters developing within an hour or in a few cases within a week after drug administration is termed as fixed drug eruptions (FDE). FDE is one of the major forms of drug-induced dermatosis. Various class of drugs that are causative agents for FDE includes antibiotics, anticonvulsants, antivirals, and Non-steroidal anti-inflammatory drugs (NSAID). FDE is easily recognized and differentiated from other drug eruptions since it does not occur voluntarily or during infection. Case report: This case report is to spotlight the case of a 52-year-old male patient who was undergoing treatment for acute gastroenteritis and suffered from FDE due to administration of IV Ofloxacin.

scholarly journals Fixed drug eruption caused by tadalafil - case report

2013 ◽  
Vol 88 (4) ◽  
pp. 617-619 ◽  
Author(s):  
Milan Bjekic ◽  
Milica Markovic ◽  
Sandra Sipetic
Keyword(s):  
Case Report ◽  
Complete Resolution ◽  
Drug Eruption ◽  
Personal History ◽  
Oral Lesions ◽  
Fixed Drug Eruption ◽  
Drug Eruptions ◽  
Short Course ◽  
Fixed Drug ◽  
Recreational Use

Fixed drug eruptions (FDE) are commonly reported type of mucocutaneous drug eruption. The aim of this paper is to present a patient with multiple mucocutaneous erythema fixum type lesions caused by oral tadalafil use. A short course of topical corticosteroid therapy resulted in complete resolution of all lesions leaving residual hyperpigmentation of the involved skin sites. Mucosal oral lesions were effectively treated with gingival hyaluronic acid 0.2% gel. Conclusion: when assessing a patient of any age with drug eruptions, a thorough personal history should be obtained, in particular data on regular or recreational use of phospodiesterase type 5 inhibitors.

scholarly journals A case of self-treatment induced oral mucosal fixed drug eruptions associated with use of tinidazole - a case report

2021 ◽  
Vol 9 (6) ◽  
pp. 1794
Author(s):  
Swathi C. Prabhu ◽  
Harshavardhan K. Shetty
Keyword(s):  
Adverse Reaction ◽  
Case Report ◽  
Oral Mucosa ◽  
Medical Practice ◽  
Drug Eruption ◽  
Case Reports ◽  
Common Site ◽  
Fixed Drug Eruption ◽  
Drug Eruptions ◽  
Fixed Drug

Fixed drug eruptions (FDE) is a type of adverse reaction to drugs encountered in medical practice. Skin, glans penis is most common site of involvement. We hereby report a case of fixed drug eruption on oral mucosa due to tinidazole, a nitroimidazole-derivative which the patient had taken as he was suffering from gastro-intestinal distress. Very limited case reports have been found in literature with respect to tinidazole causing FDE.

Phenolphthalein-Induced Fixed Drug Eruption: A Cutaneous Complication of Laxative Use in a Child

PEDIATRICS ◽  
1993 ◽  
Vol 91 (6) ◽  
pp. 1199-1201
Author(s):  
MICHAEL D. ZANOLLI ◽  
JOANNE MCALVANY ◽  
DANIEL P. KROWCHUK
Keyword(s):  
African American ◽  
Case Report ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
American Girl ◽  
Laxative Use ◽  
Dermatology Clinic ◽  
Drug Eruptions ◽  
Fixed Drug ◽  
African American Girl

Drug eruptions are a common dermatologic problem faced by pediatricians. Among the most distinctive of these is the fixed drug eruption, a cutaneous inflammatory reaction manifested by solitary or multiple, well-defined, erythematous macules that may become bullous.1,2 Lesions usually occur within a few hours of ingesting the drug, characteristically recur in the same location with each subsequent dose, and leave residual hyperpigmentation. To illustrate the importance and unique features of this unusual reaction, we report the case of a child who experienced a recurrent fixed drug eruption induced by phenolphthalein-containing, nonprescription laxatives. CASE REPORT An 8-year-old African-American girl was brought to the Dermatology Clinic for evaluation of pruritic and occasionally swollen "dark spots" that had been present on her face and arms for months.

Probable etoricoxib-induced fixed drug eruption involving the oral mucosa: A case report.

2020 ◽  
Author(s):  
Alexandra Perks ◽  
Timothy John Bates ◽  
Shireen Velangi ◽  
Rachel M Brown ◽  
Ana Poveda-Gallego
Keyword(s):  
Case Report ◽  
Oral Mucosa ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug

Fixed drug eruption due to fluconazole: A case report

2014 ◽  
Vol 4 (3) ◽  
pp. 255 ◽  
Author(s):  
Rita Vora ◽  
Malay Mehta ◽  
Nilofar Diwan ◽  
Alpa Gor ◽  
Bharat Gajjar
Keyword(s):  
Case Report ◽  
Drug Eruption ◽  
Fixed Drug Eruption ◽  
Fixed Drug
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