New Record of Bipolaris cynodontis: An Emerging Human Pathogen Causing Superficial Mycosis in North India

2021 ◽  
pp. 1-6
Author(s):  
Bharti Sharma ◽  
Skarma Nonzom
Keyword(s):  
Human Skin ◽  
Causal Agent ◽  
North India ◽  
Human Pathogen ◽  
Human Pathogens ◽  
Jammu And Kashmir ◽  
The Past ◽  
First Case ◽  
Superficial Mycosis ◽  
Dermatophytic Fungi

Superficial mycosis, a common fungal infection affecting people worldwide are prevalent in the tropical and subtropical countries, mostly caused by the dermatophytes but nowadays, there is an increase in the incidence of these infections being caused by non-dermatophytic fungi and yeasts. Among non-dermatophytes, Bipolaris species, usually known to cause diseases in plants, have also emerged as potent human pathogens in the past years. Reports on Bipolaris species associated with clinical human skin samples are rare worldwide with no reports on B. cynodontis as a causal agent of superficial human skin mycoses from India. We report the first case of superficial mycosis caused by B. cynodontis that affected the feet of a 19-year-old female student from Jammu district, Jammu and Kashmir, India. Thus, the causal agent described in the research communication constitutes a new addition to the list of pathogenic non-dermatophytes associated with human skin.

Line on Fire

2019 ◽  
Author(s):  
Happymon Jacob
Keyword(s):  
Oral History ◽  
South Asian ◽  
Empirical Data ◽  
Political Leadership ◽  
Jammu And Kashmir ◽  
The Past

The India–Pakistan border in Jammu and Kashmir (J&K) has witnessed repeated ceasefire violations (CFVs) over the past decade. Indeed, with relations between India and Pakistan degrading, CFVs have gone up exponentially. These CFVs have the potential to not only begin a crisis but also escalate an ongoing one. To make things worse, in the event of major violations, political leadership on either side often engage in high-pitched rhetoric some of which even have nuclear undertones. Using fresh empirical data and oral history evidence, this book explains the causes of CFVs on the J&K border and establishes a relationship between CFVs and crisis escalation between India and Pakistan. In doing so, the book further nuances the existing arguments about the escalatory dynamics between the two South Asian nuclear rivals. Furthermore, the book explains ceasefire violations using the concept of ‘autonomous military factors’.

Penile Lymphoepithelioma-Like Carcinoma: A Rare Case With PD-L1 Expression

2021 ◽  
pp. 106689692098834
Author(s):  
Raquel Machado-Neves ◽  
Bernardo Teixeira ◽  
Elsa Fonseca ◽  
Pedro Valente ◽  
Joaquim Lindoro ◽  
...  
Keyword(s):  
Human Papillomavirus ◽  
Tumor Cells ◽  
Rare Case ◽  
Malignant Tumors ◽  
Squamous Cell Carcinomas ◽  
The Third ◽  
The Past ◽  
First Case ◽  
Lymphoplasmacytic Infiltrate

Most malignant tumors of the penis are squamous cell carcinomas (SCC), being divided in 2 groups, one human papillomavirus (HPV)-related and another non-HPV-related, with lymphoepithelioma-like carcinoma (LELC) being one of the rarest HPV-related SCC. In this article, we report a case of a 50-year-old man who presented testicular swelling and pain for the past 3 months. A penile mass was identified, and the patient was submitted to a total penectomy. The penectomy specimen showed an ulcerated lesion at the glans reaching the cavernous bodies. Microscopic examination showed undifferentiated epithelial cells with syncytial growth pattern mix with a dense lymphoplasmacytic infiltrate, consistent with LELC. The tumor cells expressed p16 and all 3 different clones of PDL1 (22C3, SP263, and SP142). The patient is alive and well with a follow-up of 3 months. To our knowledge, this is the third LELC of the penis reported in literature and the first case reported with PDL1 expression.

scholarly journals Infective Aortic Valve Endocarditis Causing Embolic Consecutive ST-Elevation Myocardial Infarctions

2019 ◽  
Vol 2019 ◽  
pp. 1-5
Author(s):  
Kanksha Peddi ◽  
Alexander L. Hsu ◽  
Tomas H. Ayala
Keyword(s):  
Myocardial Infarction ◽  
Infective Endocarditis ◽  
Aortic Valve ◽  
Index Case ◽  
Current Treatment ◽  
Myocardial Infarctions ◽  
Treatment Modalities ◽  
The Past ◽  
First Case ◽  
St Elevation

ST-elevation myocardial infarction (STEMI) is a rare and potentially fatal complication of infective endocarditis. We report the ninth case of embolic native aortic valve infective endocarditis causing STEMI and the first case to describe consecutive embolisms leading to infarctions of separate coronary territories. Through examination of this case in the context of the previous eight similar documented cases in the past, we find that infective endocarditis of the aortic valve can and frequently affect more than a single myocardial territory and can occur consecutively. Further, current treatment modalities for embolic infective endocarditis causing acute myocardial infarction are limited and unproven. This index case illustrates the potential severity of complications and the challenges in developing standardized management for such patients.

scholarly journals B.05 Hemi-laryngopharyngeal spasm (HELPS) syndrome: The discovery, cure, and characterization of a new neurological condition

2017 ◽  
Vol 44 (S2) ◽  
pp. S11-S11
Author(s):  
C Honey ◽  
M Morrison
Keyword(s):  
Surgical Care ◽  
Review Of The Literature ◽  
The Past ◽  
First Case ◽  
Patient Reported ◽  
Operative Outcome ◽  
Small Cohort ◽  
The Common ◽  
Similar Motor

Background: We published the world’s first case of hemi-laryngpharyngeal spasm (HELPS) syndrome cured by microvascular decompression (MVD) of the Xth cranial nerve in 2016. We now present a small cohort of patients (n=3) successfully treated with surgery in order to better delineate the common characteristics of this syndrome, diagnostic tests of choice, nuances of their surgical care and outcomes of their treatment. Methods: The history and physical examination of three patients with HELPS syndrome are presented. Pre-operative laryngoscopy, neuroimaging, response to botox and intra-operative videos are detailed. Post-operative outcome and complications are presented. Results: Each patient reported similar motor (choking) and sensory (coughing) features in their history. Episodic choking relentlessly progressed over the years until it occurred while sleeping and with frightening severity prompting tracheostomy in one patient and intubation in another. A “tickling” sensation deep in the throat triggered episodic coughing that worsened over the years until it occurred while sleeping and with frightening severity (syncope and incontinence). Conclusions: A review of the literature suggests that patients with similar symptoms, often called episodic laryngospasm in the past, have been treated with psychotherapy or antacids. With the recognition that a clearly defined subset of these patients have HELPS syndrome, we can offer them the potential of a neurosurgical cure.

Prostatic Abscess in a Patient with Chronic Granulomatous Disease: A Multi-Disciplinary Intervention

2017 ◽  
Vol 84 (4) ◽  
pp. 267-269 ◽  
Author(s):  
Alberto Martini ◽  
Ioannis Katafigiotis ◽  
Sofia Kalantzi ◽  
Ioannis Anastasiou ◽  
Ioannis Adamakis ◽  
...  
Keyword(s):  
Antibiotic Therapy ◽  
Chronic Granulomatous Disease ◽  
Urine Culture ◽  
Underlying Disease ◽  
Multidrug Resistant ◽  
Granulomatous Disease ◽  
Prostatic Abscess ◽  
The Past ◽  
First Case

Introduction Chronic granulomatous disease (CGD) is a rare pathology that increases patients’ susceptibility to infections, given the inability to generate oxygen radicals to fight microorganisms. In the context of CGD, primary prostatic involvement has been described only once in the past, in a pediatric patient. Case Report We report the case of a 35-year old patient with CGD presenting with persistent fever. After hospital admission, blood and urine were sent for culture and antibiotic therapy was initiated. Patient's conditions continued to deteriorate and an aggressive antibiotic therapy was administered to treat the septic scenario. Urine culture grew a multidrug-resistant Escherichia Coli. After patient's condition improved, a CT scan was performed. The depiction showed multiple abscesses within the prostate. A rectal approach was excluded given patient's underlying disease. A TURP was performed and prostatic pathology resolved. Patient was discharged on postoperative day 14. At 6-month follow-up he hasn't experienced major infections. To the best of our knowledge, this is the first case of septic shock originating from a prostatic abscess in an adult patient with CGD. Conclusions Aggressive medical therapy along with TURP resulted curative in our case. A multi-disciplinary approach was mandatory.

Entertainment and Resonance

2021 ◽  
pp. 122-137
Author(s):  
Peter Vorderer
Keyword(s):  
Media Use ◽  
Affective States ◽  
Recent Past ◽  
The Past ◽  
First Case ◽  
Self Transcendence ◽  
Entertainment Theory

This chapter aims to differentiate between two kinds of media use experiences that in the past twenty some years have uniformly been labeled entertainment experiences. In the background of four identified fundamental assumptions in entertainment theory (entertainment as reception phenomenon, disparity between what media users want and what they should want, entertainment between approaching and avoiding affective states, entertainment as self-transcendence) media experiences are dichotomized between those that serve users’ hedonic motivations, needs, and interests and others, more fundamental experiences of resonance (which in the recent past have often been labeled eudaimonic) that connect users to the content of a media narrative and ultimately changes them. The argument is made here for communication scholars and media psychologists to refer to entertainment experiences only in the first case in order to be less vague and ambiguous in explicating entertainment theory.

Myiasis Absent Wohlfahrtiimonas Chitiniclastica Bacteremia in a Lung Cancer Patient – A Case Report

2021 ◽  
Author(s):  
Peter Dovjak ◽  
Michael Kroissenbrunner ◽  
Bernhard Iglseder
Keyword(s):  
Lung Cancer ◽  
Case Report ◽  
Cancer Patient ◽  
Lung Cancer Patient ◽  
Chronic Wounds ◽  
Lung Tumor ◽  
Personal Hygiene ◽  
Human Pathogen ◽  
Case Presentation ◽  
First Case

Abstract Background: A gruesome infection was found in a woman with advanced lung tumor and associated malnutrition. Worldwide, bacteremia with Wohlfartiimonas chitiniclastica was only found in 13 cases yet.Case presentation: This is the first case in Austria and the first case without infestation of maggots.Conclusions: This germ may be considered as an emerging human pathogen not only in patients with poor personal hygiene, difficult social circumstances, alcohol dependence or chronic wounds.AbstraktEine grauenhafte Infektion wurde bei einer Patientin mit fortgeschrittenem Lungentumor und Malnutrition gefunden. Bisher wurden weltweit erst 13 Fälle mit einer Wohlfahrtiimonas chitiniclastica - Bakteriämie beschrieben. Dieser erste Fall in Österreich manifestierte sich ohne eine Infestation mit Maden. Dieses Bakterium kann als neuer Krankheitserreger betrachtet werden, der nicht nur bei Patienten unter mangelnder Hygienebedingungen, schwierigen sozialen Verhältnissen, Alkoholabhängigkeit oder chronischen Wunden auftreten kann.

scholarly journals The Woodward technique for Sprengel deformation

2011 ◽  
Vol 2 (1) ◽  
pp. 1
Author(s):  
Marcelin Ngowe Ngowe ◽  
Ibrahim Farikou ◽  
Faustin Félicien Mouafo Tambo ◽  
Bernadette Ngo Nonga ◽  
Gervais Ondobo Andze ◽  
...  
Keyword(s):  
Cosmetic Result ◽  
Pediatric Hospital ◽  
The Past ◽  
First Case ◽  
Woodward Procedure ◽  
Surgical Unit

A case of 5-year-old boy with a left congenital undescended scapula graded Cavendish III was consulted in our unit and operated successfully with the Woodward technique. It was the first case treated by this procedure for the past 10 years, in the Pediatric Surgical Unit of the Yaounde Gyneco-Obstetric and Pediatric Hospital (Cameroon). The Woodward procedure permitted to obtain a good functional and cosmetic result.

Verapamil in Bipolar Illness

1986 ◽  
Vol 31 (5) ◽  
pp. 442-444 ◽  
Author(s):  
Leigh Solomon ◽  
Peter Williamson
Keyword(s):  
Calcium Channel ◽  
Affective Disorder ◽  
Bipolar Affective Disorder ◽  
Blocking Agent ◽  
Bipolar Illness ◽  
The Past ◽  
First Case ◽  
Treatment Of Depression ◽  
Channel Blocking ◽  
Successful Control

The authors report two cases of Bipolar Affective Disorder which were responsive to Lithium therapy in the past, but could no longer be treated with Lithium due to hyperparathyroidism in the first case and noncompliance in the second. In both cases, successful control of hypomania was achieved with Verapamil, but treatment of depression required the addition of Trazodone. The rationale for employing a calcium channel blocking agent, such as Verapamil, in bipolar illness is reviewed.

scholarly journals A place for the Bodhisatta: The local and the universal in jātaka stories

2007 ◽  
Vol 8 (1) ◽  
pp. 109-122 ◽  
Author(s):  
Naomi Appleton
Keyword(s):  
19Th Century ◽  
North India ◽  
Local Culture ◽  
Teaching Career ◽  
The Past ◽  
Multiple Audiences ◽  
The Individual

Oxford UniversityJātakas—stories about the past lives of the ‘historical’ Buddha—are often associated with specific locations, both within the land of Buddhism’s birth, and in other parts of Asia. There are records suggesting that such locations became early pilgrimage sites; contemporary sources also make reference to ‘local’ jātakas, which in many cases help to assimilate Buddhism into the local culture through its geography. In this article I will argue that it is the structure of jātaka stories that allows this localisation to take place all over Asia. I contend that since the jātakas themselves are lacking in specific external referents they can easily be given a location, whilst their framing in the ‘present’ time of the Buddha’s teaching career grounds the stories in both time and place, without infringing on the flexibility of the individual stories. This ability to provide centrally legitimated relevance for each and all contributes greatly to the popularity and endurance of the jātaka genre. The layering of meanings must remain if the stories are to accomplish this: if the stories become formally localised, for example by 19th century scholars who celebrate the jātakas’ worth as records of life in early India, the power of the stories to transcend boundaries of time and place for their multiple audiences is lost. Yet if the jātakas were not anchored in the Buddha’s teaching career in the 5th century BCE North India, their significance for Buddhists would in any case be negligible.

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