scholarly journals Perigastric Hyaline-Vascular Variant Castleman’s Disease

2021 ◽  
pp. 632-638
Author(s):  
Yu Ming Jin ◽  
Gui Ying Jing
Keyword(s):  
Histopathological Examination ◽  
Immunohistochemical Analysis ◽  
Lymphoproliferative Disease ◽  
Castleman Disease ◽  
Unknown Etiology ◽  
Mesenchymal Tumors ◽  
Imaging Characteristics ◽  
Contrast Enhanced ◽  
Hyaline Vascular Variant ◽  
Vascular Variant

Castleman disease (CD) is a rare chronic lymphoproliferative disease with unknown etiology and pathogenesis disease. When the lesion is located in the mediastinum, the diagnosis of CD is easy. However, if the lesion presents as a perigastric mass mimicking other subserosal gastric mesenchymal tumors, the diagnosis can be challenging. As few sonographic manifestations of hyaline-vascular variant CD, especially contrast-enhanced ultrasound (CEUS) imaging, as well as computed tomography (CT) and histopathological imaging, have been reported in literature, this case may provide a vivid example of a comprehensive CEUS and CT usage in the diagnosis and surgery with regard to CD. This report presents a case of a 50-year-old female diagnosed with hyaline-vascular variant CD in a random physical examination, the ultrasound examination first revealed a 24.3 mm × 15.4 mm hypoechogenic lesion abutting the stomach, esophagus, and liver, which was under the suspicion of gastrointestinal stromal tumor. Following a series of medical examinations, including CEUS, CT, postoperative histopathological examination, and immunohistochemical analysis, the patient was diagnosed with hyaline-vascular variant unicentric CD. After the mass was completely excised through laparoscopic surgery, the woman recovered very well without recurrence during a follow-up period of 15 months. Thus, mastering ultrasound and CT-imaging characteristics of CD and applying ultrasound and CT examination together would do help to preoperative diagnosis.

Castelman’s disease of the parotid gland – case report

2020 ◽  
Vol 9 (2) ◽  
pp. 62-65
Author(s):  
Paweł Krawczyński ◽  
Wojciech Brzoznowski
Keyword(s):  
Case Report ◽  
Parotid Gland ◽  
Lymph Nodes ◽  
Histopathological Examination ◽  
Lymphoproliferative Disease ◽  
Castleman Disease ◽  
Disease Entity ◽  
Gland Tumor ◽  
Parotid Gland Tumor

Castleman disease is a rare lymphoproliferative disease occurs most often in lymph nodes located in the chest. The extra-nodal form concerns 25% of diagnosed cases of this disease entity. We present the case of Castelman disease localized in the parotid gland in a 15-year-old boy, confirmed by histopathological examination, clinically progressing as a right parotid gland tumor.

scholarly journals Castleman Disease Presenting with Jaundice: A Case with the Multicentric Hyaline Vascular Variant

2007 ◽  
Vol 22 (2) ◽  
pp. 113 ◽  
Author(s):  
Jun bean Park ◽  
Jin Hyeok Hwang ◽  
Haeryoung Kim ◽  
Hyung Sim Choe ◽  
Yu Kyeong Kim ◽  
...  
Keyword(s):  
Castleman Disease ◽  
Hyaline Vascular Variant ◽  
Vascular Variant

scholarly journals Localized Castleman’s Disease in the Breast in a Young Woman

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Rafael Parra-Medina ◽  
José Ismael Guio ◽  
Patricia López-Correa
Keyword(s):  
Lymphoproliferative Disorder ◽  
Histopathological Examination ◽  
Castleman’S Disease ◽  
Unknown Etiology ◽  
Castleman's Disease ◽  
Axillary Lymphadenopathy ◽  
The Right ◽  
Slow Growing ◽  
Hyaline Vascular Variant

Castleman’s disease (CD) is a rare lymphoproliferative disorder of unknown etiology. It typically occurs in adulthood but it may also develop in childhood. Clinically, this disease may be classified as localized (unicentric) or systemic (multicentric). Six cases of breast CD have been described in the literature, and all have been reported in adults. Herein we describe the case of a 15-year-old female who presented with a slow-growing tumor in the right breast. The tumor was excised and histopathological examination demonstrated hyaline vascular variant CD. After two years of follow-up, the patient was asymptomatic without evidence of cervical or axillary lymphadenopathy.

Predominant Stroma-Rich Feature in Hyaline Vascular Variant of Castleman Disease Is Associated With Paraneoplastic Pemphigus

2020 ◽  
Vol 154 (3) ◽  
pp. 403-413
Author(s):  
Leyi Wang ◽  
Lin Nong ◽  
Furong Li ◽  
Xue Wang ◽  
Rui Wang ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Incidence Rate ◽  
Univariate Analysis ◽  
Survival Rates ◽  
Laboratory Data ◽  
Castleman Disease ◽  
Paraneoplastic Pemphigus ◽  
Histopathologic Features ◽  
Hyaline Vascular Variant ◽  
Vascular Variant

Abstract Objectives We aimed to describe the clinical and histopathologic features of Castleman disease (CD), particularly emphasizing its associations with paraneoplastic pemphigus (PNP) and prognosis. Methods We retrospectively enrolled 123 CD patients at our center. Clinical, pathologic, and laboratory data were reviewed. Results Fifty percent of the patients had PNP. Compared with those without PNP, patients with PNP-associated CD had more hyaline vascular (HV) variants (83.9% vs 57.4%), fewer mixed cellular variants (16.1% vs 24.6%), and no plasmacytic variants (0% vs 18.0%). Thirty-eight of 87 patients with the HV variant of CD (HV-CD) had stroma-rich (SR) features, and the incidence rate was higher in those with PNP-associated CD than in those without PNP (48.4% vs 13.1%, P < .001). The SR variant was associated with higher PNP-associated IgG titers than SR absence before surgery (median 1:160 vs 1:80, P = .019) or after surgery (median 1:160 vs 1:40, P = .013). The SR variant was also an unfavorable prognostic factor for CD survival in univariate analysis. The 3-year survival rates were 47.5% among those with PNP and 87.7% among those without PNP (P < .001). Conclusions PNP is associated with specific subtypes of CD and affects survival. The SR variant of HV-CD positively correlates with the incidence of PNP.

scholarly journals Hyaline vascular variant of unicentric Castleman disease of the tonsil: a case report

2019 ◽  
Vol 14 (1) ◽  
Author(s):  
Ping Li ◽  
Huaipu Liu ◽  
Hao Li ◽  
Ang Li ◽  
Guangyin Yu ◽  
...  
Keyword(s):  
Case Report ◽  
Castleman Disease ◽  
Hyaline Vascular Variant ◽  
Vascular Variant

scholarly journals Diagnostic imaging of a mass-shape hepatic steatosis in a dog treated with chemotherapy

2020 ◽  
Vol 65 (No. 5) ◽  
pp. 221-226
Author(s):  
N Lee ◽  
J Seo ◽  
J Kim ◽  
J Yoon
Keyword(s):  
Diagnostic Imaging ◽  
Hepatic Steatosis ◽  
Histopathological Examination ◽  
Liver Mass ◽  
Imaging Characteristics ◽  
Contrast Enhanced ◽  
History Of ◽  
Enhanced Computed Tomography ◽  
Patient’S History ◽  
Gland Tumour

A left medial liver mass was found through the monitoring of the metastasis in a 15-years-old, spayed female Maltese dog. The patient had a history of chemotherapy with carboplatin after surgical resection of the mammary gland tumour. Ultrasonography (US) showed a massive hyperechoic mass in the left liver. The left medial liver mass was identified as a poorly demarcated, hypoattenuated area on the non-enhanced and all the phases of contrast-enhanced computed tomography. The liver mass was surgically removed and the histopathological examination showed a fatty deposition and no evidence of neoplasm. Based on the patient’s history, diagnostic imaging and histopathological findings, the liver mass was considered as a chemotherapy-induced hepatic steatosis. This report provides the diagnostic imaging characteristics of the hepatic steatosis that could help differentiate it from a malignancy in a dog treated with chemotherapy.

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