scholarly journals Tumor Lysis Syndrome in a Low-Risk Pancreatic Cancer Patient

2021 ◽  
pp. 1310-1314
Author(s):  
Paul Travers ◽  
Alexandra Goodman ◽  
Bernard Poiesz
Keyword(s):  
Pancreatic Cancer ◽  
Risk Stratification ◽  
Treatment Initiation ◽  
Tumor Lysis Syndrome ◽  
Pancreatic Cancer Patient ◽  
Low Risk ◽  
High Grade ◽  
Tumor Lysis ◽  
Stratification System ◽  
Risk Stratification System

Tumor lysis syndrome (TLS) is the most common hematologic emergency encountered during the treatment of high-grade malignancies. While it can lead to death, the prognosis is typically excellent if caught early on in the course. Risk stratification prior to treatment initiation is paramount in deciding the utility of prophylaxis and ultimately in reducing morbidity and mortality. The following case describes the development of TLS in a patient categorized as low risk and highlights the need for further elucidation of a unified risk stratification system.

scholarly journals A Novel Validated Recurrence Stratification System Based on 18F-FDG PET/CT Radiomics to Guide Surveillance After Resection of Pancreatic Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Miaoyan Wei ◽  
Bingxin Gu ◽  
Shaoli Song ◽  
Bo Zhang ◽  
Wei Wang ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
High Risk ◽  
Risk Stratification ◽  
Cancer Patients ◽  
Fdg Pet ◽  
Resectable Pancreatic Cancer ◽  
Pet Ct ◽  
Stratification System ◽  
Fdg Pet Ct ◽  
Risk Stratification System

objectiveDespite the heterogeneous biology of pancreatic cancer, similar surveillance schemas have been used. Identifying the high recurrence risk population and conducting prompt intervention may improve prognosis and prolong overall survival.MethodsOne hundred fifty-six resectable pancreatic cancer patients who had undergone 18F-FDG PET/CT from January 2013 to December 2018 were retrospectively reviewed. The patients were categorized into a training cohort (n = 109) and a validation cohort (n = 47). LIFEx software was used to extract radiomic features from PET/CT. The risk stratification system was based on predictive factors for recurrence, and the index of prediction accuracy was used to reflect both the discrimination and calibration.ResultsOverall, seven risk factors comprising the rad-score and clinical variables that were significantly correlated with relapse were incorporated into the final risk stratification system. The 1-year recurrence-free survival differed significantly among the low-, intermediate-, and high-risk groups (85.5, 24.0, and 9.1%, respectively; p < 0.0001). The C-index of the risk stratification system in the development cohort was 0.890 (95% CI, 0.835–0.945).ConclusionThe 18F-FDG PET/CT-based radiomic features and clinicopathological factors demonstrated good performance in predicting recurrence after pancreatectomy in pancreatic cancer patients, providing a strong recommendation for an adequate adjuvant therapy course in all patients. The high-risk recurrence population should proceed with closer follow-up in a clinical setting.

scholarly journals Role of postoperative radiotherapy in pT3N0 rectal cancer: A risk‐stratification system based on population analyses

2019 ◽  
Vol 8 (3) ◽  
pp. 1024-1033 ◽  
Author(s):  
Yun‐xia Huang ◽  
Yan‐zong Lin ◽  
Jin‐luan Li ◽  
Xue‐qing Zhang ◽  
Li‐rui Tang ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Risk Stratification ◽  
Postoperative Radiotherapy ◽  
Population Analyses ◽  
Stratification System ◽  
Risk Stratification System

666 A NOVEL RISK STRATIFICATION SYSTEM FOR CHEMOTHERAPY FAILURE IN TESTICULAR GERM CELL TUMOR

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Jessica Lubahn ◽  
Nicholas Cost ◽  
Mehrad Adibi ◽  
Adam Romman ◽  
Ganesh Raj ◽  
...  
Keyword(s):  
Risk Stratification ◽  
Germ Cell ◽  
Germ Cell Tumor ◽  
Testicular Germ Cell Tumor ◽  
Cell Tumor ◽  
Testicular Germ Cell ◽  
Stratification System ◽  
Risk Stratification System

Dexamethasone-Induced Tumor Lysis Syndrome in High-Grade Non-Hodgkinʼs Lymphoma

1994 ◽  
Vol 87 (3) ◽  
pp. 409-411 ◽  
Author(s):  
IMTIAZ A. MALIK ◽  
SALEEM ABUBAKAR ◽  
FEROZ ALAM ◽  
ATA KHAN
Keyword(s):  
Tumor Lysis Syndrome ◽  
High Grade ◽  
Tumor Lysis
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