Effect of phacoemulsification on outcomes after vitrectomy with membrane peeling regarding new intraretinal cystoid changes and transient macular edema
Purpose: Aim of the present study was to analyze the effect of phacoemulsification on outcomes among patients undergoing vitrectomy with membrane peeling for idiopathic epiretinal membranes, with respect to new postoperative intraretinal cystoid changes and early transient macular edema. Procedures: This retrospective analysis included patients from six prospective studies, examining outcomes of 23G pars plana vitrectomy with membrane peeling due to idiopathic epiretinal membranes. Phacovitrectomy with membrane peeling was performed only in case of coexisting vision affecting cataract. Optical coherence tomography was performed prior to surgery, in the first week and 3 months after surgery. Results: In total, 183 patients were included. Occurrence of new postoperative intraretinal cystoid changes and early transient macular edema showed a trend to be higher among patients undergoing phacovitrectomy with membrane peeling, compared to vitrectomy with membrane peeling alone, but did not reach statistical significance (p=0.5 and p=0.186). Final BCVA 3 months after surgery was significantly lower among patients with new postoperative intraretinal cystoid changes, compared to patients without (with a median difference of 1 line between groups, p=0.016). Conclusions: New postoperative intraretinal cystoid changes and early transient macular edema are more frequent among patients undergoing phacovitrectomy with membrane peeling, compared to patients with vitrectomy with membrane peeling alone.