scholarly journals Clear Cell Chondrosarcoma with Rib Cage Metastasis: Case Report

2021 ◽  
pp. 239-243
Author(s):  
Rui Caetano de Oliveira ◽  
John Reith ◽  
José Casanova
Keyword(s):  
Case Report ◽  
Male Patient ◽  
Surgical Intervention ◽  
Clear Cell ◽  
Clinical Course ◽  
Histological Subtype ◽  
Clear Cell Chondrosarcoma ◽  
Rib Cage ◽  
Aggressive Clinical Course

Clear cell chondrosarcoma is a rare histological subtype of chondrosarcoma, usually with a relatively non-aggressive clinical course. However, infrequently they may relapse and metastasize. We describe a case of a male patient, 53 years old, with rib cage metastases of a clear cell chondrosarcoma 11 years after the first surgical intervention, and review the literature.

Follicular Lymphoma With a Burkitt Translocation—Predictor of an Aggressive Clinical Course: A Case Report and Review of the Literature

2004 ◽  
Vol 128 (2) ◽  
pp. 210-213 ◽  
Author(s):  
Peter M. Voorhees ◽  
Kathryn A. Carder ◽  
Scott V. Smith ◽  
Lanier H. Ayscue ◽  
Kathleen W. Rao ◽  
...  
Keyword(s):  
Case Report ◽  
Follicular Lymphoma ◽  
Clinical Course ◽  
Lymphoblastic Leukemia ◽  
Initial Diagnosis ◽  
Indolent Lymphoma ◽  
Review Of The Literature ◽  
Cell Type ◽  
Aberrant Expression ◽  
Aggressive Clinical Course

Abstract Follicular lymphoma is an indolent lymphoma characterized by the (14;18) translocation, which leads to aberrant expression of Bcl-2. Translocations involving 8q24 are most commonly associated with Burkitt lymphoma and result in c-Myc overexpression. We report a case of follicular lymphoma of predominant small cleaved-cell type (grade 1) associated with both a t(14;18)(q32;q21) and a t(8;22)(q24;q11). The 8q24 translocation predicted an aggressive clinical course, as the lymphoma transformed into acute lymphoblastic leukemia within a year of initial diagnosis. Routine cytogenetic analysis is recommended at initial diagnosis of follicular lymphoma to better identify abnormalities that may predict prognosis and influence therapy.

Clear Cell Chondrosarcoma: A Case Report with Topographic Analysis

1989 ◽  
Vol 39 (8) ◽  
pp. 533-538
Author(s):  
Jian Ding ◽  
Hiroshi Hashimoto ◽  
Masazumi Tsuneyoshi ◽  
Munetomo Enjoji ◽  
Sachio Masuda ◽  
...  
Keyword(s):  
Case Report ◽  
Clear Cell ◽  
Topographic Analysis ◽  
Clear Cell Chondrosarcoma

PP - PRIMARY CUTANEOUS CD8+ T-CELL LYMPHOMA: A CASE REPORT WITH UNUSUAL FACIAL INVOLVEMENT AND AN AGGRESSIVE CLINICAL COURSE

2017 ◽  
Vol 123 (2) ◽  
pp. e56
Author(s):  
DAPHINE CAXIAS TRAVASSOS ◽  
DARCY FERNANDES ◽  
ELAINE MARIA SGAVIOLI MASSUCATO ◽  
CLAUDIA MARIA NAVARRO ◽  
MIRIAN APARECIDA ONOFRE ◽  
...  
Keyword(s):  
Case Report ◽  
T Cell ◽  
Clinical Course ◽  
Cell Lymphoma ◽  
Cd8 T Cell ◽  
T Cell Lymphoma ◽  
Aggressive Clinical Course

scholarly journals Rhabdomyosarcoma of the Adult Prostate: A Case Report With Complete Molecular Profile

2019 ◽  
Vol 28 (1) ◽  
pp. 92-98 ◽  
Author(s):  
Andrea D. Olivas ◽  
Tatjana Antic
Keyword(s):  
Case Report ◽  
Clinical Course ◽  
Tumor Biology ◽  
Embryonal Rhabdomyosarcoma ◽  
Molecular Profile ◽  
Aggressive Clinical Course ◽  
The Impact

Primary rhabdomyosarcoma of the adult prostate is rare and associated with an aggressive clinical course. Given the limited number of cases reported about the prostate, little is known about the impact of molecular mutations on tumor biology and prognosis in adults. In this article, we present a case of primary embryonal rhabdomyosarcoma of the adult prostate with a complete molecular mutational profile of the tumor.

Combined Sclerosing and Spindle Cell Rhabdomyosarcoma in Previous Craniotomy Site: A Case Report and a Review of the Literature

2018 ◽  
Vol 27 (3) ◽  
pp. 328-335
Author(s):  
Hongxing Gui ◽  
Elliott Lhospital ◽  
Arthur P. Staddon ◽  
Suneel N. Nagda ◽  
Eric L. Zager ◽  
...  
Keyword(s):  
Case Report ◽  
High Frequency ◽  
Spindle Cell ◽  
Clinical Course ◽  
Review Of The Literature ◽  
Poor Clinical Outcome ◽  
Cell Components ◽  
Sclerosing Rhabdomyosarcoma ◽  
Aggressive Clinical Course ◽  
Worse Prognosis

Sclerosing rhabdomyosarcoma (RMS) is a rare subtype of RMS with unique prominent stromal hyalinization and a pseudovascular architecture. It overlaps morphologically with spindle cell RMS and poses both diagnostic and therapeutic challenges because of its rarity and aggressive clinical course. In this article, we report a case of sclerosing RMS arising from a prior craniotomy site, which demonstrated both sclerosing and spindle cell components. A literature review of RMS with sclerosing morphology identified 122 cases. Our review documents the following: sclerosing RMS occurs in both childhood and adult populations, has a predilection for the head and neck areas, and has a worse prognosis in adults. Sclerosing RMS harbors a high frequency of MYOD1 mutations, conferring a poor clinical outcome. Sclerosing RMS and spindle RMS likely represent a morphologic spectrum of one entity.

Synchronous Pulmonary Adenofibroma and Solitary Fibrous Tumor: Case Report and Review of the Literature

2018 ◽  
Vol 27 (3) ◽  
pp. 322-327 ◽  
Author(s):  
Nicholas J. Olson ◽  
Julianna M. Czum ◽  
Francine B. de Abreu ◽  
Konstantinos Linos ◽  
Candice C. Black
Keyword(s):  
Case Report ◽  
Solitary Fibrous Tumor ◽  
Clinical Course ◽  
Significant Proportion ◽  
Review Of The Literature ◽  
Single Patient ◽  
Rare Neoplasm ◽  
Fibrous Tumor ◽  
Aggressive Clinical Course

Pulmonary adenofibroma (PAF) is a rare neoplasm that may be related to solitary fibrous tumor (SFT). A subset of PAFs harbor the NAB2-STAT6 fusion that is typical of SFT, but a significant proportion do not. Their distinction is clinically important as SFTs can potentially have an aggressive clinical course, while there has been no report of a PAF behaving in a malignant fashion. We report a case of a 60-year-old male who developed a SFT and PAF in the same lung. The SFT harbored a NAB2-STAT6 fusion, while the PAF did not have any identifiable fusion. This case represents the first instance of a single patient with both of these tumors occurring simultaneously in the same lung.

scholarly journals Renal Medullary Carcinoma with an Aggressive Clinical Course: A Case Report and Review of the Literature

2017 ◽  
Vol 10 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Madhumati R. Kalavar ◽  
Sami Ali ◽  
Damoun Safarpour ◽  
Saroj Davi Kunnakkat
Keyword(s):  
Case Report ◽  
Sickle Cell ◽  
Clinical Course ◽  
Sickle Cell Trait ◽  
African Descent ◽  
Young Patients ◽  
Medullary Carcinoma ◽  
Review Of The Literature ◽  
Renal Medullary Carcinoma ◽  
Aggressive Clinical Course

Renal medullary carcinoma (RMC) is a rare, yet aggressive malignancy of the kidney that is found predominantly in young patients with African descent and sickle cell hemoglobinopathies and most specifically sickle cell trait. Due to its aggressive nature, most cases have metastasis or local invasion at the time of diagnosis. Prognosis is extremely poor with survival less than 1 year after diagnosis. Here we present a case of metastatic RMC in a 29-year-old African female. Despite chemotherapy with cisplatin, gemcitabine, and paclitaxel, and initial shrinkage of the tumor, the patient died 5 months after diagnosis.

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