Prestroke Physical Activity and Poststroke Cognitive Performance

2020 ◽  
Vol 49 (6) ◽  
pp. 632-638
Author(s):  
Andreas Gammelgaard Damsbo ◽  
Janne Kaergaard Mortensen ◽  
Kristian Lundsgaard Kraglund ◽  
Søren Paaske Johnsen ◽  
Grethe Andersen ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cognitive Impairment ◽  
Functional Outcome ◽  
Cognitive Performance ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Protective Measure ◽  
Multivariable Analyses ◽  
State Examination ◽  
Physical Activity Scale

<b><i>Introduction:</i></b> Physical activity (PA) is associated with a lower risk of stroke and stroke mortality as well as a favorable stroke outcome. PA may also prevent general cognitive decline. Poststroke cognitive impairment is both common and disabling, and focusing on all possible preventive measures is important. Studies on the effect of PA on poststroke cognitive performance are sparse, however. We therefore aimed to examine the association between prestroke PA and poststroke cognitive performance. <b><i>Methods:</i></b> We studied the correlation between prestroke PA and poststroke cognitive performance in a prespecified analysis in The Efficacy of Citalopram Treatment in Acute Ischemic Stroke (TALOS) trial. We used the Physical Activity Scale for the Elderly (PASE) to collect information on PA during the 7-day period before stroke. PA was quantified, and patients were stratified into quartiles based on their PASE score. Cognitive performance was measured using the Symbol Digit Modalities Test (SDMT) at 1 and 6 months and the Mini-Mental State Examination (MMSE) at 6 months. The functional outcome was assessed using the modified Rankin Scale (mRS). <b><i>Results:</i></b> In total, 625 of 642 patients (97%) completed the PASE questionnaire. The median age was 69 (interquartile range [IQR]: 60–77), and the median PASE score was 137 (82–205). Higher prestroke PASE quartiles (2nd, 3rd, and 4th, each compared to the 1st) were independently associated with a higher SDMT score at 1 month in the both the univariable and multivariable analyses (2nd: 3.99 points, 95% confidence interval [CI]: 1.01–6.97; 3rd: 3.6, CI: 0.6–6.61; 4th: 4.1, CI: 0.95–7.24). This association remained at 6 months. PA was not statistically associated with the MMSE score or mRS. <b><i>Conclusion:</i></b> Higher prestroke PA was associated with a better cognitive performance as measured by the SDMT at 1 and 6 months poststroke. We found no significant association between prestroke PA and functional outcome. Our results are encouraging and support further investigations of PA as a protective measure against poststroke cognitive impairment.

scholarly journals Impact of cognitive performance on the functional capacity of an elderly population in Natal, Brazil

2008 ◽  
Vol 66 (4) ◽  
pp. 809-813 ◽  
Author(s):  
Keithlen Cruz Moreira de Castro ◽  
Ricardo Oliveira Guerra
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Performance ◽  
Functional Capacity ◽  
Elderly Population ◽  
Population Sample ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Elderly Persons ◽  
Cross Sectional ◽  
State Examination

Functional incapacity and cognitive impairment are conditions related to the process of human aging. Cognitive impairment is considered an important predicitve factor for functional impairment in elderly populations. This cross-sectional study analyzes the association between cognitive performance and functional capacity in an elderly population sample in Natal, Brazil. A total of 213 elderly persons were assessed by the BOAS Multidimensional Questionnaire (Brazil Old Age Schedule) and the Mini-Mental State Examination (MMSE). The results of multivariate analysis and linear regression showed that age and schooling level are factors associated with cognitive performance in the elderly of this study. The final explicative model, elaborated by logistic regression, found that cognitive performance was the only predicitve variable of functional incapacity for the activities of daily living even when adjusted for sociodemographic variables.

scholarly journals To evaluate the utility of 10 warning signs questionnaire in assessment of cognitive function among elderly people

2016 ◽  
Vol 7 (01) ◽  
pp. 168-170
Author(s):  
Sunil Kumar Raina ◽  
Vishav Chander
Keyword(s):  
Cognitive Impairment ◽  
Elderly People ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Warning Signs ◽  
Correlation Data ◽  
Urban Rural ◽  
State Examination

ABSTRACT Introduction: Routine screening of high-risk elderly people for early cognitive impairment using mini-mental state examination (MMSE) and its modifications may be constrained by demographic and other variables. Warning signs (as reported by family/caregivers) may be a useful alternative. The present data analysis was carried out with the aim to identify the role of 10 warning signs screen as an alternative tool for screening for cognitive impairment among elderly. Materials and Methods: For the purpose of this analysis (correlation), data available with us from a study conducted on the elderly population (60 years and above) from selected geographical areas (Migrant, Urban, Rural, and Tribal) of Himachal Pradesh was used. Results: A high statistically significant was found between scores on 10 warning signs screen and Hindi mental state examination/Bharmouri mental state examination (modifications of MMSE). Conclusions: Ten warning signs screen can be an important screening total for assessment of cognitive impairment in the elderly Indians.

scholarly journals Early Cognitive Impairment after Intracerebral Hemorrhage in the INTERACT1 Study

2017 ◽  
Vol 44 (5-6) ◽  
pp. 320-324 ◽  
Author(s):  
Shoujiang You ◽  
Xia Wang ◽  
Richard I. Lindley ◽  
Thompson Robinson ◽  
Craig S. Anderson ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Intracerebral Hemorrhage ◽  
Mini Mental State Examination ◽  
Multivariable Analysis ◽  
The Elderly ◽  
Background Data ◽  
Acute Intracerebral Hemorrhage ◽  
State Examination ◽  
Intensive Blood Pressure

Background: Data on cognitive impairment after acute intracerebral hemorrhage (ICH) are limited. This study is aimed at determining the frequency and predictors of cognitive impairment among participants of the pilot phase, Intensive Blood Pressure (BP) Reduction in Acute Cerebral Hemorrhage Trial (INTERACT1). Methods: INTERACT1 was an open randomized trial of early intensive (target systolic BP <140 mm Hg) compared with contemporaneous guideline-recommended BP lowering in 404 patients with elevated systolic BP (150–220 mm Hg) within 6 h of ICH onset. Cognitive impairment was defined by scores ≤24 on the Mini-Mental State Examination (MMSE) assessed by interview on follow-up at 90 days. Results: A total of 231 (64.5%) of 358 90-day survivors had MMSE scores for analyses, and 75 (32.5%) had cognitive impairment. In multivariable analysis, older age (OR 2.48, 95% CI 1.73–3.56 per 10-year increase; p < 0.001), female sex (OR 2.06, 95% CI 1.00–4.23; p = 0.049), prior ICH (OR 2.87, 95% CI 1.08–7.65; p = 0.035), high baseline National Institute of Health Stroke Scale score (OR 1.06, 95% CI 1.00–1.13; p = 0.044), and high mean systolic BP over the first 24 h post-randomization (OR 1.34, 95% CI 1.07–1.68/10 mm Hg increase; p = 0.011) were independently associated with cognitive impairment. Conclusions: One third of patients have significant cognitive impairment early after ICH, which is more frequent in the elderly, females, those with prior ICH, and more severe initial neurological deficit and with persistently high early systolic BP.

scholarly journals Combining functional scales and cognitive tests in screening for mild cognitive impairment at a university-based memory clinic in Brazil

2008 ◽  
Vol 30 (4) ◽  
pp. 346-349 ◽  
Author(s):  
Izabella Dutra de Abreu ◽  
Paula Villela Nunes ◽  
Breno Satler Diniz ◽  
Orestes Vicente Forlenza
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Diagnostic Accuracy ◽  
Cognitive Decline ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Elderly Subjects ◽  
Cognitive State ◽  
State Examination

OBJECTIVE: To determine the diagnostic accuracy of the Mini-Mental State Examination combined to the Informant Questionnaire on Cognitive Decline in the Elderly for the identification of mild cognitive impairment. METHOD: 191 elderly subjects were assessed with the Mini-Mental State Examination, and their informants were assessed with the Informant Questionnaire on Cognitive Decline in the Elderly. Subjects were divided into three groups according to their cognitive state (controls: n = 67, mild cognitive impairment: n = 65 and dementia: n = 59), which was ascertained by clinical and neuropsychological evaluation. The diagnostic accuracy of each test in the discrimination of diagnostic groups (mild cognitive impairment vs. controls, mild cognitive impairment vs. dementia and dementia vs. controls) was examined with the aid of ROC curves. We additionally verified if the combination of both tests would increase diagnostic accuracy for mild cognitive impairment and control identification. RESULTS: The combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly scores did not increase the Mini-Mental State Examination diagnostic accuracy in the identification of patients with mild cognitive impairment. CONCLUSIONS: The present data do not warrant the combination of the Mini-Mental State Examination and the Informant Questionnaire on Cognitive Decline in the Elderly as a sufficient diagnostic tool in the diagnostic screening for mild cognitive impairment.

scholarly journals Creativity, paranormal beliefs and cognitive impairment in the elderly

2015 ◽  
Vol 5 (2) ◽  
pp. 253-265
Author(s):  
Inmaculada Méndez ◽  
Julia García-Sevilla ◽  
Juan P. Martínez ◽  
Isabel García-Munuera ◽  
Ana Mª Bermúdez ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Religious Beliefs ◽  
Mini Mental State Examination ◽  
Belief System ◽  
The Elderly ◽  
Cognitive Status ◽  
Sociodemographic Characteristics ◽  
Paranormal Beliefs ◽  
The Relationship ◽  
State Examination

In the case of older people, aesthetic thought and creativity are ways to keep mind and imagination active by contributing to prevent cognitive decline. Furthermore, having a religious belief system or even a belief system or paranormal experiences has proved to be beneficial for the health of the elderly. The objective was to study the relationship between creativity, degree of cognitive impairment and paranormal beliefs. The existence of differences depending on sociodemographic characteristics was analyzed. A group of 36 elderly people (16 men) aged between 66 and 95 years were administered the Mini-Mental State Examination (MEC), the CREA Test and the Paranormal Beliefs Scale. The main outcomes include that: those with better cognitive status are more creative; the less creative subjects had more traditional religious beliefs and even greater superstition; the elderly with better cognitive status were the least superstitious. It is remarkable that men were more creative, while women excelled in traditional religious beliefs. The study allows reflecting on the importance of professionals who work with the elderly to carry out programs to encourage creativity and even collect information about the belief system.

scholarly journals The Montreal Cognitive Assessment (MoCA-Ina) versus the Mini-Mental State Examination (MMSE-Ina) For Detecting Mild Cognitive Impairment among The Elderly

2021 ◽  
Vol 20 (1) ◽  
pp. 164-169
Author(s):  
Ida Untari ◽  
Achmad Arman Subijanto ◽  
Diah Kurnia Mirawati ◽  
Rossi Sanusi
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Assessment ◽  
Mini Mental State Examination ◽  
Medical Science ◽  
The Elderly ◽  
Rank Test ◽  
Cognitive Tests ◽  
Level Of Education ◽  
And Gender ◽  
State Examination

Background: There are many neuropsychological instruments are used for screening cognitivefunctions in adults, with or without health problems such asthe MMSE-Ina and MoCA-Ina. Objectives:This study was designed to test the correlations and differences between MMSE-Inaand MoCA-Ina for early detection of decreasing cognitive function in the elderly. Methods: Total278 subjects were randomly selected from the 17 sub dictricts of Surakarta Municipality, CentralJava, Indonesia. Data collection was carried out in December 2018 and January 2019, withallsubjects individually interviewed using two cognitive tests (which lasted 30 – 45 minutes) alongwith physical and neurological examinations. The MMSE-Ina and MoCA-Ina scores of eachparticipant were correlated using the non-parametric Spearman rank test. Both scores werecompared based on level of education and gender. Results: The MoCa-Ina detected using MCIwas 215 (77.3%) while MMSE-Ina was 189 (68%), with 176 (63.3%) in severe 10 (3.5%).This study also showed a strong correlation between the MMSE-Ina and MoCA-Ina scores (r= 0.633 p < 0.000). The cut pointin this study were 23/24 for the MMSE-Ina and 25/26 for theMoCA-Ina which was less than 23 and 25,indicated cognitive impairment. Conclusion: TheMoCA-Ina is usedto screen cognitive impairment in the elderly. Bangladesh Journal of Medical Science Vol.20(1) 2021 p.164-169

scholarly journals The Effect of Low Impact Aerobic Exercise on Elderly with Dementia Cognitive Function

2020 ◽  
Vol 8 (1) ◽  
Author(s):  
Raden Ayu Tanzila ◽  
Sheilla Yonaka Lindri ◽  
Nindia Rahma Putri
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Cognitive Function ◽  
Aerobic Exercise ◽  
Elderly People ◽  
Memory Impairment ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Quasi Experimental ◽  
State Examination

In the elderly population, at least 10% of those over 65 years old and 50% of those over 80 years old experience a decline in cognitive function that varies from a cognitive decline due to normal aging (age-associated memory impairment/AAMI) to a mild cognitive decline (mild cognitive impairment/MCI) and dementia. Dementia is an intellectual disorder that affects the cognitive function, memory, language function, and visuospatial function that causes irreversible changes. Many studies have stated that lifestyle management in the form of increased physical activity has a protective effect on impaired cognitive functions, inhibits cognitive function decline, and even improves cognitive function in healthy elderly people and elderly with mild cognitive impairment to dementia. Low impact aerobic exercise is a physical activity that is useful and suitable for the elderly. This study aimed to determine the effect of low impact aerobic exercise on the cognitive function of elderly people with dementia. This was a quasi-experimental study with one group pretest-posttest method that involved elderly people from Tresna Werdha Teratai Palembang, South Sumatera, Indonesia who were selected based on the inclusion and exclusion criteria (n=38) from December 2018 to February 2019. Treatment provided was a low impact aerobic exercise 3 times a week for 5 weeks. Dementia was then measured before and after treatment using the Mini-mental State Examination (MMSE). The mean values of gymnastics before the treatment and after the treatment were 18.36±4.559 and 19.69±5.724, respectively. A p value of 0.000 was obtained using the Wilcoxon test. In summary, low impact aerobic exercise influences the cognitive function of the elderly with dementia. PENGARUH SENAM AEROBIK LOW IMPACT TERHADAP FUNGSI KOGNITIF USILA DENGAN DEMENSIAPada usia lanjut (usila), sedikitnya 10% dari yang berusia lebih dari 65 tahun dan 50% dari yang berusia lebih dari 80 tahun mengalami penurunan fungsi kognitif yang bervariasi mulai dari penurunan kognitif karena penuaan normal (age-associate memory impairment/AAMI) serta penurunan kognitif ringan (mild cognitive impairment/MCI) hingga demensia. Demensia adalah gangguan intelektual yang meliputi fungsi kognitif, daya ingat, bahasa, fungsi visuospasial, dan bersifat ireversibel. Banyak studi menyatakan bahwa manajemen gaya hidup berupa peningkatan aktivitas fisik mempunyai efek protektif terhadap gangguan fungsi kognitif, menghambat penurunan fungsi kognitif, serta bahkan meningkatkan fungsi kognitif pada usila yang sehat dan usila dengan penurunan fungsi kognitif ringan sampai demensia. Senam aerobik low impact merupakan aktifitas fisik yang bermanfaat dan cocok diberikan kepada usila. Penelitian ini bertujuan mengetahui pengaruh senam aerobik low impact terhadap fungsi kognitif usila dengan demensia. Penelitian ini merupakan studi quasi-experimental dengan metode pretest-posttest one group yang melibatkan usila dari Tresna Werdha Teratai Palembang, Sumatera Selatan, Indonesia yang dipilih berdasar atas kriteria inklusi dan eksklusi (n=38) dari bulan Desember 2018 hingga Februari 2019. Perlakuan yang diberikan berupa senam aerobik low impact 3 kali per minggu selama 5 minggu. Demensia kemudian diukur sebelum dan sesudah perlakuan menggunakan Mini-mental State Examination (MMSE). Nilai rerata senam sebelum perlakuan dan setelah perlakuan adalah 18,36±4,559 dan 19,69±5,724 masing-masing. Nilai p=0,000 didapatkan dengan menggunakan Uji Wilcoxon. Simpulan, senam aerobik low impact memengaruhi fungsi kognitif usila dengan demensia.

PREVALENCE OF COGNITIVE IMPAIRMENT AND ASSOCIATED FACTORS AMONG THE ELDERLY IN PHU AN COMMUNE, PHU VANG DISTRICT, THUA THIEN HUE PROVINCE IN 2016

2018 ◽  
Vol 8 (5) ◽  
pp. 72-77
Author(s):  
Tu Huynh Thi Thanh ◽  
Khanh Doan Vuong Diem ◽  
Hanh Nguyen Thi ◽  
Nguyen Le Thi Thao ◽  
Linh Tran Thi Phuong ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Associated Factors ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
Living Alone ◽  
Health Checkup ◽  
Related Factors ◽  
Increasing Risk ◽  
State Examination

Background: Cognitive impairment is one of the major causes of disability and dependency among the elderly. Cognitive impairment not only seriously affects the quality of the patient’s life but also has a great impact on physical, psychological and economic situation of family caregivers and society. There is little research on the prevalence of cognitive impairment and its related factors in Vietnam. Aims: The aims of this study were: (i) To examine the prevalence of cognitive impairment among the elderly in Phu An commune, Phu Vang district, Thua Thien Hue province (ii) To examine some associated factors of cognitive impairment among participants. Methods: A randomly selected sample of 343 people aged 60 years and over living in Phu An commune were interviewed and examined. MMSE test (Mini Mental State Examination) was used as a screening instrument for cognitive impairment. Multilogistic regression was undertaken for exploring associated factors of cognitive impairment. Results: The overall prevalence of cognitive impairment was 19.5%. Increasing age, inconvenient marital status (single, widowed, separate), living alone were associated with increasing risk of acquiring cognitive impairment. Conclusion: In this population, probable cognitive impairment is common. Health education program and routine health checkup for early detection and intervention of cognitive impairment are urgently needed among the elderly in Vietnam. Key words: Cognitive impairment, prevalence, associated factors, elderly people

scholarly journals Comparison of the Mini Mental State Examination and depressive symptoms between high cardiovascular risk and healthy community elderly groups

2008 ◽  
Vol 2 (4) ◽  
pp. 294-299 ◽  
Author(s):  
Amanda Lucas da Costa ◽  
Juliana Santos Varela ◽  
Osmar Mazetti ◽  
Luciane Restelatto ◽  
Andry Fitterman Costa ◽  
...  
Keyword(s):  
Risk Factors ◽  
Depressive Symptoms ◽  
Cardiovascular Risk ◽  
Cognitive Performance ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
High Cardiovascular Risk ◽  
Healthy Community ◽  
The Relationship ◽  
State Examination

Abstract The aging of the population is a universal phenomenon with direct consequences upon the public health system. One of the main repercussions of the growth in this sector of the population is the increased prevalence of disorders such as dementia and depression which are very frequent among the elderly. The relationship between cardiovascular risk factors, dementia and depression have been addressed in many recent investigations. Objectives: To evaluate the relationship of cognitive performance and depressive symptoms with cardiovascular risk in the elderly. Methods: 94 high cardiovascular risk elderly patients and 160 healthy community elderly were evaluated cross-sectionally. The Mini Mental State Examination (MMSE) and the Geriatric Depression Scale (GDS-15) were used as the main measures. The cutoff for presence of depression was 6 on the GDS. Results: The high cardiovascular risk elderly group showed significantly lower scores on the MMSE (p<0.001) and was significantly associated to depression (p<0.001), independently of education. The logistic regression analysis for depression as the dependent variable, age and group (healthy community or high cardiovascular risk elderly) were kept in the final equation. Higher age (Odds Ratio=0.92; 95% CI 0.86-0.98) and high cardiovascular risk elderly (OR=2.99; 95% CI 1.36-6.59) were associated to depression. Conclusions: The present findings corroborate the different cognitive performance of elderly with high cardiovascular risk factors and the association of depressive symptoms with this group.

scholarly journals Cognitive impairment, the Mini-Mental State Examination and socio-demographic and dental variables in the elderly in Brazil

Gerodontology ◽  
2011 ◽  
Vol 29 (2) ◽  
pp. e34-e40 ◽  
Author(s):  
Leonardo de Paula Miranda ◽  
Marise F. Silveira ◽  
Thatiane L. Oliveira ◽  
Sâmia F. F. Alves ◽  
Hercílio M. Júnior ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mental State ◽  
Mini Mental State Examination ◽  
The Elderly ◽  
State Examination
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