scholarly journals Are We Overradiating Patients with Irritable Bowel Syndrome?

2020 ◽  
pp. 1-6
Author(s):  
Yousaf B. Hadi ◽  
Adnan Aman Khan ◽  
Syeda F.Z. Naqvi ◽  
Salman Khan ◽  
Jesse Thompson ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Radiation Exposure ◽  
Care Center ◽  
Tertiary Care ◽  
Pain Medication ◽  
Comorbid Anxiety ◽  
Medical Radiation ◽  
Increased Risk ◽  
Irritable Bowel ◽  
Medical Radiation Exposure

<b><i>Introduction:</i></b> Protracted exposures to small doses of radiation, even cumulative effective doses (CED) as low as 50–100 mSv, may increase the risk for malignancy. Medical radiation exposure has not been rigorously examined for patients with irritable bowel syndrome (IBS). We examined medical radiation exposure in patients with IBS at a tertiary care center in the USA. <b><i>Methods:</i></b> Patients diagnosed with IBS at our institute from 2009 to 2018 were included in a retrospective cohort study. Medical charts were examined to calculate total and annual CED. <b><i>Results:</i></b> 221 patients were included; mean CED was 40.32 mSv (SD: 54.36). Fifty-nine participants (26.7%) received &#x3e;50 mSv of CED with 27 participants (12.2%) exceeding 100 mSv. Conventional imaging, nuclear medicine, and fluoroscopy accounted for 74.08, 12.93, and 12.98% of total CED, respectively. CT scans contributed to 66.61% of total CED. Outpatient orders accounted for 37.96% of total CED, while 31.4% of total CED was ordered in the emergency department. Population-specific high total CED was calculated as 105.65 mSv. Multivariable binomial logistic regression model found that comorbid anxiety, chronic pain medication use, and diarrhea-predominant IBS were independently positively associated with population-specific high CED exposure. No significant temporal trend in peri-diagnostic mean CED was found. <b><i>Conclusion:</i></b> Patients with IBS receive high amounts of medical radiation, with 1 in 4 patients reaching at-risk levels of 50 mSv or more. Usage of pain medication at home, comorbid anxiety, and IBS-D are independently linked to an increased risk of high CED.

scholarly journals Psychiatric Disorders in Patients with Irritable Bowel Syndrome at a Tertiary Care Centre in Bangladesh

2020 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Psychiatric Disorders ◽  
Psychiatric Illness ◽  
Care Center ◽  
General Health Questionnaire ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Asian Countries ◽  
Significant Difference ◽  
Irritable Bowel

Background/Aims: Irritable bowel syndrome (IBS) is one of the common functional gastrointestinal disorder. Psychosomatic illness is a common association with IBS. Although studies in both western and Asian countries showed significant coexisting psychiatric illness in IBS patients, such studies are scarce in south-east Asian countries like Bangladesh. So, the aim of this study was to find out the association of psychiatric co-morbidities in patients with IBS in a tertiary care center. Methods: This was a cross-sectional study conducted from July 2017 to January 2019. Patients were selected from the dedicated IBS clinic of a tertiary care center in Bangladesh. IBS population were enrolled according to the Rome-IV diagnostic criteria. Relevant history, physical examination and investigations were done to exclude organic diseases. A psychiatric assessment of all the study subjects was done by a clinical psychiatrist using the General Health Questionnaire (GHQ)-12. Results: Ninety-six IBS patients were enrolled in this study. The mean age was 33.51±9.87 years. Male outnumbered female (85.4% vs 14.6%). IBS diarrhea (83.3%) was predominant in this study. Approximately 60.41% of IBS patients had different psychiatric illnesses. Major depressive disorder (27.1%) and generalized anxiety disorder (15.6%) were the most common psychiatric illness in this study. There was no significant difference in psychiatric comorbidities among various IBS types. Conclusions: A significant number of IBS patients have co-morbid psychiatric disorders. So, IBS patients should meticulously be screened for such co-morbidities for effective and integrated management.

scholarly journals Psychiatric Co-morbidity in Patients With Irritable Bowel Syndrome at a Tertiary Care Center in Northern India

2017 ◽  
Vol 23 (4) ◽  
pp. 555-560 ◽  
Author(s):  
Yuman Kawoos ◽  
Zaid A Wani ◽  
Showkat A Kadla ◽  
Irfan A Shah ◽  
Arshad Hussain ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Northern India ◽  
Co Morbidity ◽  
Irritable Bowel

scholarly journals Psychiatric Disorders in Patients with Irritable Bowel Syndrome at a Tertiary Care Centre in Bangladesh

2020 ◽  
Vol 4 (1) ◽  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Psychiatric Disorders ◽  
Psychiatric Illness ◽  
Care Center ◽  
General Health Questionnaire ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Asian Countries ◽  
Significant Difference ◽  
Irritable Bowel

Background/Aims: Irritable bowel syndrome (IBS) is one of the common functional gastrointestinal disorder. Psychosomatic illness is a common association with IBS. Although studies in both western and Asian countries showed significant coexisting psychiatric illness in IBS patients, such studies are scarce in south-east Asian countries like Bangladesh. So, the aim of this study was to find out the association of psychiatric co-morbidities in patients with IBS in a tertiary care center. Methods: This was a cross-sectional study conducted from July 2017 to January 2019. Patients were selected from the dedicated IBS clinic of a tertiary care center in Bangladesh. IBS population were enrolled according to the Rome-IV diagnostic criteria. Relevant history, physical examination and investigations were done to exclude organic diseases. A psychiatric assessment of all the study subjects was done by a clinical psychiatrist using the General Health Questionnaire (GHQ)-12. Results: Ninety-six IBS patients were enrolled in this study. The mean age was 33.51±9.87 years. Male outnumbered female (85.4% vs 14.6%). IBS diarrhea (83.3%) was predominant in this study. Approximately 60.41% of IBS patients had different psychiatric illnesses. Major depressive disorder (27.1%) and generalized anxiety disorder (15.6%) were the most common psychiatric illness in this study. There was no significant difference in psychiatric comorbidities among various IBS types. Conclusions: A significant number of IBS patients have co-morbid psychiatric disorders. So, IBS patients should meticulously be screened for such co-morbidities for effective and integrated management.

Declining Rates of Referral for Irritable Bowel Syndrome Without Constipation at a Tertiary Care Center

2018 ◽  
Vol 64 (1) ◽  
pp. 182-188
Author(s):  
Sun Jung Oh ◽  
Vartan C. Tashjian ◽  
James Mirocha ◽  
Menachem Nagar ◽  
Ruchi Mathur ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Care Center ◽  
Tertiary Care ◽  
Tertiary Care Center ◽  
Irritable Bowel

Reproductive Effects of Low-to-Moderate Medical Radiation Exposure

2012 ◽  
Vol 19 (36) ◽  
pp. 6171-6177 ◽  
Author(s):  
G. Latini ◽  
L. Dipaola ◽  
A. Mantovani ◽  
E. Picano
Keyword(s):  
Radiation Exposure ◽  
Reproductive Effects ◽  
Medical Radiation ◽  
Medical Radiation Exposure

scholarly journals Irritable bowel syndrome and Parkinson’s disease risk: register-based studies

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Bojing Liu ◽  
Arvid Sjölander ◽  
Nancy L. Pedersen ◽  
Jonas F. Ludvigsson ◽  
Honglei Chen ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Irritable Bowel Syndrome ◽  
Case Control Study ◽  
Case Control ◽  
Twin Registry ◽  
Increased Risk ◽  
Irritable Bowel ◽  
Nested Case Control ◽  
Control Study ◽  
Swedish Twin Registry

AbstractTo examine whether irritable bowel syndrome (IBS) was related to the future risk of Parkinson’s disease (PD), we conducted a nested case-control study in the Swedish total population including 56,564 PD cases identified from the Swedish Patient Register and 30 controls per case individually matched by sex and year of birth. Odds ratios (ORs) with 95% confidence intervals (CIs) for having a prior diagnosis of IBS were estimated using conditional logistic regression. We furthermore conducted a cohort study using the Swedish Twin Registry following 3046 IBS patients identified by self-reported abdominal symptoms and 41,179 non-IBS individuals. Through Cox proportional hazard models, we estimated hazard ratios (HRs) and 95% CIs for PD risk. In the nested case-control study, 253 (0.4%) PD cases and 5204 (0.3%) controls had a previous IBS diagnosis. IBS diagnosis was associated with a 44% higher risk of PD (OR = 1.44, 95% CI 1.27–1.63). Temporal relationship analyses showed 53% and 38% increased risk of PD more than 5 and 10 years after IBS diagnosis, respectively. In the cohort analysis based on the Swedish Twin Registry, there was no statistically significantly increased risk of PD related to IBS (HR = 1.25, 95% CI = 0.87–1.81). Our results suggest a higher risk of PD diagnosis after IBS. These results provide additional evidence supporting the importance of the gut–brain axis in PD.

scholarly journals Risks of Major Mental Disorders and Irritable Bowel Syndrome among the Offspring of Parents with Irritable Bowel Syndrome: A Nationwide Study

2021 ◽  
Vol 18 (9) ◽  
pp. 4679
Author(s):  
Ta-Chuan Yeh ◽  
Ya-Mei Bai ◽  
Shih-Jen Tsai ◽  
Tzeng-Ji Chen ◽  
Chih-Sung Liang ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Mental Disorders ◽  
Autism Spectrum ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Early Implementation ◽  
Increased Risk ◽  
Nationally Representative ◽  
Irritable Bowel

Irritable bowel syndrome (IBS) is a functional bowel disorder that is highly comorbid with mental disorders. However, few studies have examined the risk of attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), bipolar disorder, major depressive disorder (MDD), and schizophrenia in the offspring of parents with IBS. We used nationally representative cross-sectional survey data to analyze cross-generational transmission patterns of both IBS and major mental disorders. Odds ratio (OR) was calculated by using logistic regression models with adjustment for potential confounding factors. Offspring of parents with IBS were more likely to develop IBS themselves (OR = 2.41, 95% confidence interval (CI), 2.09–2.78), ADHD (OR = 1.33, 95% CI, 1.08–1.62), and MDD (OR = 1.32, 95% CI, 1.04–1.68) than the controls. Data stratification by parental sex revealed that paternal IBS increased risk of ADHD (OR = 1.34, 95% CI, 1.01–1.77) in the offspring, while maternal IBS increased the risk of MDD (OR = 1.51, 95% CI, 1.11–2.06). This is the first study to reveal parental IBS is associated with IBS, ADHD, and MDD among offspring, suggesting the necessity for early implementation of prevention strategies for at-risk children.

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