scholarly journals A Case Series of “Solitary Idiopathic Choroiditis” and Proposal of a Nomenclature Change to “Idiopathic Scleroma”

2020 ◽  
pp. 1-6
Author(s):  
Emma Duignan ◽  
Roderick O’Day ◽  
Thomas Moloney ◽  
Waheeda Rahman ◽  
Bertil Damato
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Enhanced Depth Imaging ◽  
Consecutive Series ◽  
Optical Coherence ◽  
Electronic Patient Records ◽  
Basal Diameter ◽  
The United Kingdom ◽  
Ophthalmic Hospital ◽  
Active Inflammation

<b><i>Objective:</i></b> To define the characteristics of solitary idiopathic choroiditis (SIC) in a consecutive series of patients and propose a nomenclature change to idiopathic scleroma. <b><i>Materials and Methods:</i></b> Electronic patient records were retrospectively interrogated to identify all patients diagnosed with SIC between 2002 and 2019 in a tertiary referral ophthalmic hospital in the United Kingdom. <b><i>Results:</i></b> Thirty-four eyes of 34 patients were found to have SIC. The mean age at diagnosis was 48 years (range 24–78) and 23 patients (68%) were female. All lesions were located posterior to the equator, most frequently in the inferotemporal quadrant (13 eyes, 38%). The lesions had a mean largest basal diameter of 1.2 ± 0.4 disc diameters (range 0.5–2) and their distance to the optic disc had a mean of 1.2 ± 0.9 disc diameters (range 0–3.3). All lesions were intrascleral on enhanced depth imaging optical coherence tomography, demonstrating a hypo-reflective zone within the sclera, with an underlying hyper-reflective zone in some cases. No lesion enlarged or developed features consistent with active inflammation after a median follow-up time of 0.9 years (range 0–16.8). <b><i>Discussion/Conclusion:</i></b> Optical coherence tomography shows SIC to be an intrascleral lesion. Furthermore, we found no evidence of any inflammatory component. A nomenclature change to idiopathic scleroma is appropriate to prevent unnecessary investigation.

Ultra-low-dose (boom-boom) radiotherapy for choroidal lymphoma in three consecutive cases

2019 ◽  
pp. 112067211988898 ◽  
Author(s):  
Xiaolu Yang ◽  
Lauren A Dalvin ◽  
Li-Anne S Lim ◽  
Arman Mashayekhi ◽  
Jerry A Shields ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Visual Acuity ◽  
Low Dose ◽  
Case Series ◽  
B Cell Lymphoma ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Low Dose Radiotherapy ◽  
Imaging Optical Coherence Tomography

Purpose: To describe the outcome of ultra-low-dose (boom-boom) radiotherapy for choroidal lymphoma. Methods: Retrospective series of three consecutive patients with biopsy-proven choroidal lymphoma treated with ultra-low-dose radiotherapy. Results: The three patients (two male, one female) of mean age 70 years (range, 64–74 years) demonstrated presenting visual acuity in the affected eye between 20/40 and 20/50. The choroidal lymphoma was unilateral in all cases and presented with multifocal yellow patchy choroidal infiltration, located in all four quadrants and measuring mean 2.9 mm (range, 1.9–4.0 mm) in thickness by ultrasonography. Anterior epibulbar extension of 5 mm diameter was noted in one case. By enhanced depth imaging optical coherence tomography, the choroidal infiltration demonstrated classic undulating appearance (n = 3), with subretinal fluid (n = 2) and intraretinal edema (n = 1). There was no systemic lymphoma in any case. Biopsy was performed in all three cases and was diagnostic (n = 1) or suggestive (n = 2) of B-cell lymphoma. Management involved ultra-low-dose radiotherapy (4 Gy delivered in two fractions, “boom-boom”). On follow-up (mean = 14 months, range = 6–24 months), complete tumor regression on ophthalmoscopy was documented in all three cases, with enhanced depth imaging optical coherence tomography and ultrasonography demonstrating evidence of lymphoma resolution and visual acuity improvement to 20/25–20/40. There were no radiation complications. Conclusion: In this small case series, ultra-low-dose (boom-boom) radiotherapy was effective for choroidal lymphoma with favorable response and minimal side effects.

Optical coherence tomography angiography of choroidal nodules in neurofibromatosis type-1: A case series

2021 ◽  
pp. 112067212110307
Author(s):  
Francisco Javier Moreno-Morillo ◽  
José Ignacio Fernández-Vigo ◽  
Bárbara Burgos-Blasco ◽  
Carlos Llorente-La Orden ◽  
Beatriz Vidal-Villegas ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Neurofibromatosis Type 1 ◽  
Optical Coherence Tomography Angiography ◽  
Case Series ◽  
Neurofibromatosis Type ◽  
Vessel Density ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Near Infrared Reflectance

Purpose: To describe optical coherence tomography angiography (OCTA) findings in the retina and choroid of patients with neurofibromatosis type 1 (NF1). Methods: We describe a series of four patients diagnosed with NF1 and choroidal nodules who underwent a comprehensive ophthalmic evaluation including a retinal multimodal imaging study based on retinography, near-infrared reflectance imaging (NIR), enhanced depth imaging (EDI) optical coherence tomography (OCT) and OCTA. Results: Patients were three women and one man aged 36–47 years. In all patients, the choroidal nodules were not visible in retinographies but easily detectable with NIR, appearing as multiple bright patches. On OCTA, we observed reduced vessel density in the choriocapillaris in zones where choroidal nodules appeared in OCT images. In one patient, a corkscrew vessel was visible in the superficial capillary plexus. Conclusion: Choriocapillaris vessel density was reduced in zones where choroidal nodules occur in NF1 patients. Further work is needed to clarify the clinical relevance of this finding.

Feasibility and Clinical Utility of Ultra-Widefield–Navigated Swept-Source Optical Coherence Tomography Imaging

2021 ◽  
pp. 247412642199733
Author(s):  
Kyle D. Kovacs ◽  
M. Abdallah Mahrous ◽  
Luis Gonzalez ◽  
Benjamin E. Botsford ◽  
Tamara L. Lenis ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Clinical Utility ◽  
Clinical Decision Making ◽  
Imaging System ◽  
Imaging Modality ◽  
Case Series ◽  
Subretinal Fluid ◽  
Optical Coherence ◽  
Swept Source ◽  
Oct Imaging

Purpose: This work aims to evaluate the clinical utility and feasibility of a novel scanning laser ophthalmoscope-based navigated ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) imaging system. Methods: A retrospective, single-center, consecutive case series evaluated patients between September 2019 and October 2020 with UWF SS-OCT (modified Optos P200TxE, Optos PLC) as part of routine retinal care. The logistics of image acquisition, interpretability of images captured, nature of the peripheral abnormality, and clinical utility in management decisions were recorded. Results: Eighty-two eyes from 72 patients were included. Patients were aged 59.4 ± 17.1 years (range, 8-87 years). During imaging, 4.4 series of images were obtained in 4.1 minutes, with 86.4% of the image series deemed to be diagnostic of the peripheral pathology on blinded image review. The most common pathologic findings were chorioretinal scars (18 eyes). In 31 (38%) eyes, these images were meaningful in supporting clinical decision-making with definitive findings. Diagnoses imaged included retinal detachment combined with retinoschisis, retinal hole with overlying vitreous traction and subretinal fluid, vitreous inflammation overlying a peripheral scar, Coats disease, and peripheral retinal traction in sickle cell retinopathy. Conclusions: Navigated UWF SS-OCT imaging was clinically practical and provided high-quality characterization of peripheral retinal lesions for all eyes. Images directly contributed to management plans, including laser, injection or surgical treatment, for a clinically meaningful set of patients (38%). Future studies are needed to further assess the value of this imaging modality and its role in diagnosing, monitoring, and treating peripheral lesions.

Spectral Domain Optical Coherence Tomography Findings in a Case Series of Patients with Bilateral Diffuse Uveal Melanocytic Proliferation

2014 ◽  
Vol 22 (6) ◽  
pp. 490-493 ◽  
Author(s):  
Zaid Shalchi ◽  
Manoharan Shunmugam ◽  
Omar A. Mahroo ◽  
Robert J. McDonald ◽  
Mahmut Dogramaci ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Spectral Domain ◽  
Optical Coherence

Line‐field confocal optical coherence tomography of sebaceous hyperplasia: a case series

2021 ◽  
Author(s):  
Clément Lenoir ◽  
Gwendoline Diet ◽  
Elisa Cinotti ◽  
Linda Tognetti ◽  
Carmen Orte Cano ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Line Field

Line‐field confocal optical coherence tomography for non‐invasive diagnosis of lichenoid dermatoses of the childhood: A case series

2021 ◽  
Author(s):  
Linda Tognetti ◽  
Andrea. Carraro ◽  
Elisa Cinotti ◽  
Mariano Suppa ◽  
Veronique Marmol ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Case Series ◽  
Optical Coherence ◽  
Line Field ◽  
Non Invasive

scholarly journals In vivo analysis of glaucoma-related features within the optic nerve head using enhanced depth imaging optical coherence tomography

PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180128 ◽  
Author(s):  
Tiago S. Prata ◽  
Flavio S. Lopes ◽  
Vitor G. Prado ◽  
Izabela Almeida ◽  
Igor Matsubara ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
In Vivo Analysis ◽  
Imaging Optical Coherence Tomography

CHOROIDAL LYMPHOMA SHOWS CALM, RIPPLED, OR UNDULATING TOPOGRAPHY ON ENHANCED DEPTH IMAGING OPTICAL COHERENCE TOMOGRAPHY IN 14 EYES

Retina ◽  
2014 ◽  
Vol 34 (7) ◽  
pp. 1347-1353 ◽  
Author(s):  
Carol L. Shields ◽  
Sruthi Arepalli ◽  
Marco Pellegrini ◽  
Arman Mashayekhi ◽  
Jerry A. Shields
Keyword(s):  
Optical Coherence Tomography ◽  
Enhanced Depth Imaging ◽  
Optical Coherence ◽  
Depth Imaging ◽  
Imaging Optical Coherence Tomography
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