scholarly journals Diagnosis, Background, and Treatment of Hypothalamic Damage in Craniopharyngioma

2020 ◽  
Vol 110 (9-10) ◽  
pp. 767-779 ◽  
Author(s):  
Eva-Marie Erfurth
Keyword(s):  
Science ◽  
1971 ◽  
Vol 174 (4008) ◽  
pp. 523-525 ◽  
Author(s):  
J. F. Marshall ◽  
B. H. Turner ◽  
P. Teitelbaum

2017 ◽  
Vol 87 (4) ◽  
pp. 359-366 ◽  
Author(s):  
Cecilia Follin ◽  
Sigridur Fjalldal ◽  
Daniel Svärd ◽  
Danielle van Westen ◽  
Sanaz Gabery ◽  
...  

1969 ◽  
Vol 4 (1) ◽  
pp. 101-103 ◽  
Author(s):  
David Quartermain ◽  
George Wolf ◽  
John Keselica

Life Sciences ◽  
1977 ◽  
Vol 20 (8) ◽  
pp. 1377-1382 ◽  
Author(s):  
John F. Marshall ◽  
Seymour M. Antelman ◽  
Neil E. Rowland ◽  
David J. Edwards

Author(s):  
Eva Marie Erfurth

AbstractA craniopharyngioma (CP) is an embryonic malformation of the sellar and parasellar region. The annual incidence is 0.5–2.0 cases/million per year and approximately 60% of CP is seen in adulthood. The therapy of choice is surgery, followed by cranial radiotherapy in about half of the patients. Typical initial manifestations at diagnosis in children are symptoms of elevated intracranial pressure, visual disturbances and hypopituitarism. CPs have the highest mortality of all pituitary tumours. The standardised overall mortality rate varies from 2.88 to 9.28 in cohort studies. Adults with CP have a 3–19-fold higher cardiovascular mortality in comparison to the general population. Women with CP have an even higher risk. The long-term morbidity is substantial with hypopituitarism, increased cardiovascular risk, hypothalamic damage, visual and neurological deficits, reduced bone health and reduction in quality of life and cognitive function.


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