scholarly journals Association of Frontal Fibrosing Alopecia with Facial Papules and Lichen Planus Pigmentosus in a Caucasian Woman

2020 ◽  
Vol 6 (6) ◽  
pp. 379-383
Author(s):  
Anna Elisa Verzì ◽  
Francesco Lacarrubba ◽  
Federica Dall’Oglio ◽  
Giuseppe Micali

<b><i>Introduction:</i></b> Frontal fibrosing alopecia (FFA) is a lymphocytic primary cicatricial alopecia typically involving the frontotemporal hairline. It may be associated with the presence of facial papules (FP) that clinically appear as noninflammatory, monomorphic, white-yellowish papules. Lichen planus pigmentosus (LPPigm) is characterized by the presence of asymptomatic grayish pigmented macules, predominantly in sun-exposed and flexural areas. <b><i>Case Report:</i></b> A 58-year-old, Caucasian, phototype III woman presented with a symmetrical, band-like, frontotemporal alopecia with regression of the hairline; bilateral eyebrow loss; diffuse, symmetrical hyperpigmentation of the face; and some asymptomatic, flesh-colored, monomorphic papules on the chin. Based on clinical, dermoscopic, and histological findings, the diagnosis of FFA associated with FP and LPPigm was established. <b><i>Discussion/Conclusion:</i></b> The peculiarity of our report is represented by the triple association of FFA, FP, and LPPigm in a Caucasian skin type III woman, as it has been rarely reported. Clinicians should be aware of this association also in subjects with phototype ≤III, as its recognition may be useful for diagnostic and prognostic purposes: the observation of LPPigm of the face may suggest to check for early FFA, and in case of FFA associated with FP, a poorer FFA prognosis may likely be expected.

2019 ◽  
Vol 41 (2) ◽  
pp. 296-299
Author(s):  
Julia Izadora da Silva Martins ◽  
Isabela Maria Bertoglio ◽  
Amanda Carolina Damasceno Zanuto Guerra ◽  
Mariana Espiga Maioli ◽  
Vinicius Daher Alvares Delfino

ABSTRACT Introduction: Purpura fulminans (PF) is a rapid progressive thrombotic disease in which hemorrhagic infarction of the skin and disseminated intravascular coagulation (DIC) occurs. It can potentially cause acute kidney injury (AKI). However, there is no description in the medical literature of renal histological findings of PF. Case report: A 20-year-old female patient, previously healthy, was admitted to the emergency department (ED) with odynophagia, fever, generalized myalgia and anuria, which evolved with the appearance of purpuric plaques on the face and limbs. She required dialysis on admission. Laboratorial tests showed anemia, leukocytosis, thrombocytopenia, and elevation of lactic dehydrogenase (LDH). The purpuric lesions became bullous with ruptures and then necrotic and erosive, reaching the dermis, subcutaneous tissue and musculature, until bone exposure. There was no improvement with initial antibiotic therapy aimed at the treatment of meningococcemia. Thrombotic microangiopathy (TMA) and PF were then suspected. The patient remained in daily dialysis, requiring plasmapheresis. After sustained improvement of the thrombocytopenia, she underwent renal biopsy, which was not compatible with TMA, characterizing possible PF. A complete recovery of the renal function was achieved and cutaneous sequels were treated with grafts. Conclusion: When thrombotic and hemorrhagic phenomena overlap, obtaining a renal biopsy can be difficult. However, in the presented case, the biopsy allowed the exclusion of AKI caused by TMA, presenting for the first time, histological findings compatible with PF.


2019 ◽  
Vol 7 (18) ◽  
pp. 3061-3063 ◽  
Author(s):  
Uwe Wollina ◽  
Claudia Krönert ◽  
Jacqueline Schönlebe ◽  
Aleksandra Vojvodic ◽  
Torello Lotti

BACKGROUND: Cutaneous squamous cell carcinoma (SCC) is the second most common malignancy of skin. Although a major risk factor is a chronic exposure to ultraviolet radiation, preexistent chronic inflammatory disorders may also possess an increased risk for SCC. That is not the case for cutaneous lichen planus in contrast to oral lichen planus and oral SCC.  CASE REPORT: We report the case of an 87-year-old Caucasian woman presenting with a giant verrucous tumour on the left ankle. She suffered from long-standing disseminated lichen planus. Histology confirmed the diagnosis of SCC on partly verrucous lichen planus. The course was complicated due to sepsis. An emergency transfemoral amputation became necessary. The patients survived and could be released into her nursery. A literature review underlined the rarity of SCC on lichen planus of the skin. Most of these rare cases were in patients in their second half of life on the lower legs. Hypertrophic lichen plnaus was overrepresented.   CONCLUSIONS: Although very rare by number, SCC can complicate lichen planus and lead to the life-threatening situation. Atypical verrucous lesions on lichen planus warrant a histologic analysis. Surgery is the treatment of choice for cutaneous SCC.


2012 ◽  
Vol 87 (2) ◽  
pp. 313-314 ◽  
Author(s):  
Ana Maria Costa Pinheiro ◽  
Larissa Araujo Lobato ◽  
Tatiana Cristina Nogueira Varella

Dermoscopy is a method of increasing importance in the diagnoses of cutaneous diseases. On the scalp, dermoscopic aspects have been described in psoriasis, lichen planus, seborrheic dermatitis and discoid lupus. We describe the "comma" and "corkscrew hair" dermoscopic aspects found in a child of skin type 4, with tinea capitis.


F1000Research ◽  
2014 ◽  
Vol 3 ◽  
pp. 76
Author(s):  
Matthew Hughes ◽  
Jerad M. Gardner ◽  
Ling Gao

We report the case of a 49-year-old male with clinical and histological findings consistent with hypertrophic lupus erythematosus (HLE). HLE must be clinically and histologically differentiated from keratoacanthoma, hypertrophic lichen planus, squamous cell carcinoma and plaque type psoriasis. CD123 positivity and transepidermal elimination of elastin have recently been reported as tools to distinguish HLE. Interestingly, in this case, biopsies of two separate lesions failed to reveal these two features. The etiology of this discrepancy is unknown and further studies are needed to clarify the utility of CD123 positivity and transepidermal elimination of elastin in the diagnosis of hypertrophic lupus erythematosus.


1998 ◽  
Vol 37 (04) ◽  
pp. 141-145
Author(s):  
F. J. C. Pallarés ◽  
A. R. Bartual ◽  
Susana Tenes Rodrigo ◽  
F. J. Ampudia-Blasco ◽  
C. R. de Ávila y Ávalos ◽  
...  

SummaryA case of a 49-year-old man suffering from bilateral adrenocortical carcinoma with local and secondary rapid progression is reported. The results of adrenocortical scintigraphy (NP 59) and histological findings allowed the diagnosis. This case report and a literature review showed the importance of using adrenocortical scintigraphy as a complementary imaging procedure of CT or MR images.


ORL ro ◽  
2020 ◽  
Vol 3 (48) ◽  
pp. 15
Author(s):  
Corina I. Cucu ◽  
Liliana Gabriela Popa ◽  
Călin Giurcăneanu ◽  
Vladimir S. Ibric Cioran ◽  
Cristina Beiu ◽  
...  

Author(s):  
Luca Tomassini ◽  
Daniele Paolini ◽  
Anna Maria Manta ◽  
Edoardo Bottoni ◽  
Costantino Ciallella

AbstractRust stains are marks left by firearms in case of prolonged contact with the cutaneous surfaces. These peculiar signs along with other well-documented findings can guide the medical examiner in the determination of the manner of death, especially in case of firearm suicide. This paper presents the case of a 33-year-old male soldier who committed suicide by using a short-barreled weapon, whose trigger remained in contact with the first finger of his right hand, leading to the formation of a rust stain that perfectly reproduced its design. The forensic examination of the scene, the external cadaveric inspection, and the autopsy are described. For the evaluation of the histological findings typical of rust spots, the authors decided to replicate the phenomenon in an experimental setting using porcine skin. In order to provide an exhaustive overview on the formation and the features of rust stains, a review of the forensic literature concerning this rare mark was performed.


2020 ◽  
Vol 7 (1) ◽  
pp. 134-138
Author(s):  
G. Miotti ◽  
N. Zingaretti ◽  
G. F. Guarneri ◽  
V. Manfrè ◽  
E. Errichetti ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document