scholarly journals Perforated Goblet Cell Carcinoid of the Appendix

2020 ◽  
Vol 14 (2) ◽  
pp. 354-360
Author(s):  
Kimitoshi Kubo ◽  
Noriko Kimura ◽  
Masato Suzuoki ◽  
Soichiro Matsuda ◽  
Momoko Tsuda ◽  
...  
Keyword(s):  
Lymph Node ◽  
Goblet Cell ◽  
Histopathological Examination ◽  
Lower Abdominal Pain ◽  
Residual Tumor ◽  
Ileocecal Resection ◽  
Goblet Cell Carcinoid ◽  
High Grade Fever ◽  
Perforated Appendix ◽  
Laparoscopic Ileocecal Resection

Goblet cell carcinoid (GCC) of the perforated appendix is rare, and its pathological features and prognosis remain poorly described. A 71-year-old woman was admitted to our hospital for right lower abdominal pain, vomiting, and high-grade fever. She was diagnosed with acute appendicitis and underwent emergency laparoscopic appendectomy. Intraoperative examination revealed an enlarged and perforated appendix. Histopathological examination revealed GCC of the appendix with subserosal invasion. She underwent laparoscopic ileocecal resection with lymph node dissection (D3) following appendectomy. Histopathological findings showed no residual tumor or lymph node metastases. To the best of our knowledge, this report is a valuable addition to the GCC literature, describing a case of GCC of the appendix presenting as perforated appendix.

Goblet cell carcinoid of the rectum with lymph node metastasis: Report of a case

Surgery Today ◽  
2011 ◽  
Vol 41 (9) ◽  
pp. 1284-1289 ◽  
Author(s):  
Takumi Yamabuki ◽  
Makoto Omi ◽  
Atsuya Yonemori ◽  
Satoshi Hayama ◽  
Soichi Murakami ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Goblet Cell ◽  
Goblet Cell Carcinoid ◽  
Node Metastasis

scholarly journals Perforated Goblet Cell Carcinoid Tumors of the Appendix: Navigating the Management Conundrum

2017 ◽  
Vol 102 (3-4) ◽  
pp. 131-136
Author(s):  
Suman B. Koganti ◽  
Brian F. Gilchrist ◽  
Tresara C. Bell
Keyword(s):  
Goblet Cell ◽  
Residual Disease ◽  
Progression Free Survival ◽  
Right Hemicolectomy ◽  
Goblet Cell Carcinoid ◽  
Cross Sectional ◽  
Free Survival ◽  
Cross Sectional Imaging ◽  
Perforated Appendix

Appendix is the most common site of occurrence for a goblet cell carcinoid tumor. A diagnosis of an appendiceal goblet cell carcinoid is made in retrospect the majority of the time. These tumors are best treated with a right hemicolectomy and adjuvant therapies tailored according to the presence or absence of residual disease. Presentation as a perforated appendix is seen in 16% of these tumors. The natural history and the ideal management strategy in such a scenario are not well described. In those with peritoneal spread cytoreductive surgery with HIPEC (hyperthermic intraperitoneal chemotherapy) offers the best disease-free and progression-free survival. Close follow-up with cross-sectional imaging helps in identifying recurrences at the earliest. Multimodality management involving patient participation in every aspect of care accomplishes high-value care in the treatment of these tumors.

scholarly journals Co-Occurrence of Submucosal Schwannoma and Low-Grade Mucinous Neoplasm in the Appendix, a Clinical Conundrum : A Case Report

2020 ◽  
pp. 1-4
Author(s):  
Akitoshi  Nankaku ◽  
Akitoshi  Nankaku ◽  
Haruhiko Sugimura ◽  
Harutaka Inoue ◽  
Naoki Teratani ◽  
...  
Keyword(s):  
Histopathological Examination ◽  
Epigastric Pain ◽  
Relevant Literature ◽  
Ileocecal Resection ◽  
Low Grade ◽  
Clinical Images ◽  
Appendiceal Tumor ◽  
Mucinous Neoplasm ◽  
Radiological Images ◽  
Laparoscopic Ileocecal Resection

Two and more types of tumors rarely occur in the appendix, a constrained space of the human body. We experienced a rare co-occurrence of schwannoma and low-grade mucinous neoplasm (LAMN) in the appendix and obtained a lesson to scrutinize the radiological images in the follow-up period. A computer tomography (CT) performed for surveillance of bile duct stone of a 68-year-old man incidentally detected the appendiceal tumor, which characteristics were not clear at that time, 1-year before admission because of epigastric pain due to acute cholecystitis. CT showed enlargement of tumor in the appendix, and laparoscopic ileocecal resection and cholecystectomy were performed under the diagnosis of acute cholecystectomy and appendiceal tumor. Histopathological examination revealed two types of appendiceal tumors, schwannoma and low-grade appendiceal neoplasm. To the best of our knowledge, co-occurrence of schwannoma and LAMN has never been reported and this complicated our interpretation of clinical images during the course. We report a clinical lesson in handling this rare combination of tumors in the appendix with the relevant literature.

scholarly journals A Large Lymph Node Metastasis from a Carcinoid Tumor Treated by Laparoscopic Ileocecal Resection

2016 ◽  
Vol 77 (8) ◽  
pp. 1985-1989
Author(s):  
Kenta MATSUSHITA ◽  
Toshiyuki YAGI ◽  
Kazuya FUJIKI ◽  
Tomoya KODA ◽  
Yoichiro KAWASHITA ◽  
...  
Keyword(s):  
Lymph Node ◽  
Lymph Node Metastasis ◽  
Carcinoid Tumor ◽  
Ileocecal Resection ◽  
Node Metastasis ◽  
Laparoscopic Ileocecal Resection ◽  
Large Lymph Node

scholarly journals Two cases of goblet cell carcinoid of the appendix performed a laparoscopy assisted ileocecal resection.

2002 ◽  
Vol 63 (4) ◽  
pp. 927-931
Author(s):  
Maki MURAKAMI ◽  
Yasuhiro MUNAKATA ◽  
Ken HAYASHI ◽  
Hideki NISHIMURA ◽  
Emi MACHIDA
Keyword(s):  
Goblet Cell ◽  
Ileocecal Resection ◽  
Goblet Cell Carcinoid

scholarly journals Goblet cell carcinoid of the rectum: a case report

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Yoshiyuki Inoue ◽  
Hisanaga Horie ◽  
Yuko Homma ◽  
Ai Sadatomo ◽  
Makiko Tahara ◽  
...  
Keyword(s):  
Case Report ◽  
Goblet Cell ◽  
Goblet Cell Carcinoid

scholarly journals Multiple peritoneal dissemination of T2 colorectal cancer without lymph node metastases: a case report

2020 ◽  
Vol 2020 (7) ◽  
Author(s):  
Yosuke Namba ◽  
Yuzo Hirata ◽  
Shoichiro Mukai ◽  
Toshihiro Nishida ◽  
Syo Ishikawa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Lymph Node ◽  
Lymph Node Metastases ◽  
Peritoneal Dissemination ◽  
Abdominal Cavity ◽  
Muscularis Propria ◽  
Ileocecal Resection ◽  
Pathology Report ◽  
Ascending Colon ◽  
Node Metastases

Abstract Most cases of peritoneal dissemination of colorectal cancers are from T3 or T4 tumors. A 61-year-old woman was admitted for examination of a positive fecal occult blood test. Colonoscopy showed an ascending colon tumor that was diagnosed as an adenocarcinoma with massive submucosal invasion. Imaging modality revealed numerous nodules throughout the abdominal cavity. Peritoneal dissemination of the ascending colon or ovarian cancer and pseudomyxoma peritonei were considered in the preoperative differential diagnoses, and laparoscopic ileocecal resection was performed. Intraperitoneal observation revealed numerous white nodules in the peritoneum, omentum and Douglas fossa. Both the nodules and tumor were diagnosed as mucinous carcinoma based on a pathology report. The tumor invasion depth was limited to muscularis propria, and no regional lymph node metastasis was detected. Peritoneal dissemination of the ascending colon cancer was considered. We report a rare case of multiple peritoneal dissemination of T2 colorectal cancer without lymph node metastases.

scholarly journals Adenocarcinoma Ex Goblet Cell Carcinoid of Appendix: Two Case Reports

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Yu-Ting Wang ◽  
Yi-Ru Li ◽  
Tuan-Ying Ke
Keyword(s):  
Acute Appendicitis ◽  
Acute Abdomen ◽  
Goblet Cell ◽  
Case Reports ◽  
Biological Behavior ◽  
Rare Tumor ◽  
Goblet Cell Carcinoid

Adenocarcinoma ex goblet cell carcinoid is a rare tumor incidentally found in specimens of appendicitis. Most patients present with acute abdomen, similar to acute appendicitis. Here we present two cases, which were found incidentally after operation. We give a brief summary about clinical and biological behavior of this entity.

684 MODERATELY DIFFERENTIATED ESOPHAGEAL SQUAMOUS CELL CARCINOMA HAS A POOR PROGNOSIS AFTER NEOADJUVANT CHEMORADIOTHERAPY

2021 ◽  
Vol 34 (Supplement_1) ◽  
Author(s):  
Xue-feng Leng ◽  
Tianqin Mao ◽  
Jiaxin Yan ◽  
Xuefeng Leng ◽  
Yongtao Han
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Node ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Neoadjuvant Chemoradiotherapy ◽  
Residual Tumor ◽  
Lymph Node Status ◽  
Pathological Characteristics ◽  
Poorly Differentiated

Abstract   Neoadjuvant chemoradiotherapy (NCRT) plus surgery is the standard treatment for esophageal squamous cell carcinoma (ESCC); however, further analysis is needed to detail the histopathological characteristics of ESCC and their clinical significance after NCRT. This study aimed to present the pathological characteristics of ESCC and their association with prognosis after NCRT. Methods All patients with ESCC who underwent NCRT followed by surgical resection at Sichuan Cancer Hospital (China) from January 2018 to December 2019 were included. Resection specimens of both the primary disease and lymph nodes were re-evaluated by an experienced pathologist. After NCRT, the pathological characteristics of the residual tumor were evaluated based on the Japanese residual tumor pattern, Mandard tumor regression grade (Mandard-TRG), local inflammatory infiltration classification, and lymph node status. Results Among the 103 patients with ESCC included in this study, the pathological complete response (pCR) rate was 34% (35/103). The pCR rate of patients with poorly differentiated tumors (31/72) was higher (43.1%) than that of patients with well or moderately differentiated tumors (P < 0.05). The residual tumor rate was 66% (68/103). A positive correlation was noted between the Japanese residual tumor pattern and Mandard-TRG (Kendall’s tau-b = 0.857, P < 0.001). Tumor infiltration depth, lymph node positivity, moderate differentiation, and tumor recurrence were associated with poor oncological outcomes (P < 0.05). Conclusion Patients with poorly differentiated tumors can obtain an excellent short-term response; however, they have extremely poor long-term survival. For patients with moderately differentiated tumors, both the short- and long-term outcomes are poor. Lymph node status after NCRT is a prognostic factor for ESCC treated with NCRT.

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